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* In ''Webcomic/ChampionsOfFaraus'', Mr.X uses [[FusionDance spirit melding]], a process used to combine [[OurSpiritsAreDifferent different spirits together]] into more powerful ones, to create his “experiments”. Said experiments include not only spirits, but objects, animals, and [[spoiler:people]], which Karla notes ''should'' be impossible.
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[[folder:Web Comics]]
* ''Webcomic/IslaAukate'':
** The Darnathi use a process called "prototyping" to hybridize their colony missions with the planet's native lifeforms, both to adapt to the microbiome and to blend in. For most Darnathi on Earth that means they went from lizard-like amphibians to HumanAliens, though Sagitar and some of the second fleet used the genomes of Aukate's anthropomorphic animals after landing there.
** Rain, Darius' adopted pegasus daughter, went through prototyping to make her bipedal and improve her forehooves' dexterity, making her 10% Darnathi (from Darius) in the process.
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* ''Film/CaptainMarvel2019'' stays true to Carol's original backstory with her being a human who became a Kree hybrid via a blood transfusion.

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* ''Film/CaptainMarvel2019'' stays true to Carol's original backstory with her being a human who became a part Kree hybrid via a blood transfusion.



* ''Videogame/{{Elsword}}'': Ciel, normally a human, becomes a half-demon after forming a soul-contract with the demoness Lu.
* ''Videogame/HonkaiImpact3rd'': the game has various cases of artificial hybrids between human and "Honkai Beasts", which give them extra strength.
** In the present time, Theresa Apocalypse is an ArtificialHuman made by splicing the genes of a legendary Valkyrie, Kallen Kaslana, with that of an Emperor-class Honkai Beast, codenamed "Vishnu". This gives her super strength and HealingFactor, as well as natural resistance to the Honkai's influence. Later, the story introduces Olenyeva Twins, who had Honkai Beast cells grafted onto their bodies when they were younger; they have more outward physical traits of Honkai Beasts than Theresa.
** In the distant past, there existed "Fusion Warriors", frontline Honkai fighters who are infused with Honkai Beast genomes, greatly empowering them and giving them resistance to the Honkai. The legendary hero, Kevin Kaslana, was one such case; later, the Kaslana bloodline is said to have inherited the potential strength from such hybrid, but only a few have "unlocked" its full potential, such as Siegfried Kaslana.



* ''Videogame/{{Elsword}}'': Ciel, normally a human, becomes a half-demon after forming a soul-contract with the demoness Lu.
* ''Videogame/HonkaiImpact3rd'': the game has various cases of artificial hybrids between human and "Honkai Beasts", which give them extra strength.
** In the present time, Theresa Apocalypse is an ArtificialHuman made by splicing the genes of a legendary Valkyrie, Kallen Kaslana, with that of an Emperor-class Honkai Beast, codenamed "Vishnu". This gives her super strength and HealingFactor, as well as natural resistance to the Honkai's influence. Later, the story introduces Olenyeva Twins, who had Honkai Beast cells grafted onto their bodies when they were younger; they have more outward physical traits of Honkai Beasts than Theresa.
** In the distant past, there existed "Fusion Warriors", frontline Honkai fighters who are infused with Honkai Beast genomes, greatly empowering them and giving them resistance to the Honkai. The legendary hero, Kevin Kaslana, was one such case; later, the Kaslana bloodline is said to have inherited the potential strength from such hybrid, but only a few have "unlocked" its full potential, such as Siegfried Kaslana.

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Compare MixAndMatchMan, MixAndMatchCritters, FleshGolem and FrankensteinsMonster when the "hybrid" part is more physically blatant.

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Compare OurWerebeastsAreDifferent, MonstrousHumanoid, MixAndMatchMan, MixAndMatchCritters, FleshGolem and FrankensteinsMonster when the "hybrid" part is more physically blatant.


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* ''Videogame/HonkaiImpact3rd'': the game has various cases of artificial hybrids between human and "Honkai Beasts", which give them extra strength.
** In the present time, Theresa Apocalypse is an ArtificialHuman made by splicing the genes of a legendary Valkyrie, Kallen Kaslana, with that of an Emperor-class Honkai Beast, codenamed "Vishnu". This gives her super strength and HealingFactor, as well as natural resistance to the Honkai's influence. Later, the story introduces Olenyeva Twins, who had Honkai Beast cells grafted onto their bodies when they were younger; they have more outward physical traits of Honkai Beasts than Theresa.
** In the distant past, there existed "Fusion Warriors", frontline Honkai fighters who are infused with Honkai Beast genomes, greatly empowering them and giving them resistance to the Honkai. The legendary hero, Kevin Kaslana, was one such case; later, the Kaslana bloodline is said to have inherited the potential strength from such hybrid, but only a few have "unlocked" its full potential, such as Siegfried Kaslana.

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May overlap with BioAugmentation.

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May overlap with BioAugmentation.
BioAugmentation. May occur through FusionDance.


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* ''Videogame/{{Elsword}}'': Ciel, normally a human, becomes a half-demon after forming a soul-contract with the demoness Lu.
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** Played straight with Miguel O'Hara, a.k.a. ComicBook/SpiderMan2099, who has 50% spider DNA (though still look thoroughly human) after the FreakLabAccident that gave him his powers.

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** Played straight with Miguel O'Hara, a.k.a. ComicBook/SpiderMan2099, who has 50% spider DNA (though still look looks thoroughly human) after the FreakLabAccident that gave him his powers.

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* Downplayed with ''ComicBook/SpiderMan''. Though Peter Parker is still considered a human, since the spider bite that gave him his powers his genetic code has a very small percentage of spider DNA.

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* Downplayed with ''ComicBook/SpiderMan''. Though Peter Parker is still considered a human, since the spider bite that gave him his powers his genetic code has a very small percentage of spider DNA. The same applies to most other Spider-people.
** Played straight with Miguel O'Hara, a.k.a. ComicBook/SpiderMan2099, who has 50% spider DNA (though still look thoroughly human) after the FreakLabAccident that gave him his powers.
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* In the ''Disney/{{Zootopia}}'' AU ''[[https://www.fanfiction.net/s/13056744/1/Ouroboros-the-Endless-Cycle Ouroboros: The Endless Cycle]]'', Judy becomes part fox after she is bitten by a venomous chimera and Nick saves her by transmuting the bitten arm and a few of her internal organs into copies of his own.

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* In the ''Disney/{{Zootopia}}'' ''WesternAnimation/{{Zootopia}}'' AU ''[[https://www.fanfiction.net/s/13056744/1/Ouroboros-the-Endless-Cycle Ouroboros: The Endless Cycle]]'', Judy becomes part fox after she is bitten by a venomous chimera and Nick saves her by transmuting the bitten arm and a few of her internal organs into copies of his own.
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* Several characters in ''Manga/{{Dorohedoro}}'' are humans who have been partially transmuted by mages wanting to 'experiment', often giving them animal body parts as a result. TheHero of the story, Caiman, is one such person and has a lizard head on top of an otherwise human body.
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Compare MixAndMatchMan, MixAndMatchCritters, FleshGolem and FrankensteinsMonster when the "hybrid" part is more physically blatant.

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* The warrioresses in ''Manga/{{Claymore}}'' are created in this way. They are half human and half a yoma. And they are trained to kill pure yoma because [[ToServeMan they eat human guts]].



* While most hanyou are born in ''Manga/InuYasha'' as a child of a human and a [[{{Youkai}} youkai]], there are also those who were once human. They offered a pact to the lower youkai. [[PuppeteerParasite Their soul in exchange for a demonic body]]. [[BigBad Naraku]] was born this way, but the anime also shows two other unnaturally-created hanyou, namely Sara Asano and Tsubaki.



* Ken Kaneki from ''Manga/TokyoGhoul'' was a normal human being. After an accident that almost killed him, he is given organs from a [[OurGhoulsAreCreepier ghoul]] and becomes a human-ghoul hybrid in the process.

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* Shinichi and Migi from ''Manga/{{Parasyte}}'' merge more and more until they are a mix of human and parasite.
* Ken Kaneki from ''Manga/TokyoGhoul'' was a normal human being. After an accident that almost killed him, he is given organs from a [[OurGhoulsAreCreepier ghoul]] and becomes a human-ghoul hybrid in the process.


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* The first mendrites in the German SF series ''Literature/{{Maddrax}}'' were still created artificially, hybrids of humans and [[FishPeople hydrites]]. The mendrites seen later in the plot have been naturally born.


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* In ''Series/BuffyTheVampireSlayer'', the fourth season has Adam. He is a mix of humans, machines and demons, and was assembled in an underground secret lab.
** ''Series/{{Angel}}'' later shows Cordelia. She magically becomes a half-demon. As a result, she has powerful, magical powers, unlike the naturally born half-demons, but no [[SuperStrength super strength]].


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* The supersoldiers in ''Series/TheXFiles'' have been artificially created. Before, they were ordinary humans.


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* Avatar Wan from ''WesternAnimation/TheLegendOfKorra'' was the first avatar. And he was created because when he was a human, he allied himself with Raava, and merged with her into a being.

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* ''Series/DoctorWho'': In [[Recap/DoctorWhoS30E13JourneysEnd "Journey's End"]], a "biological metacrisis" turns [[spoiler:Donna Noble half-Time Lord]] and also creates a [[spoiler:half-human clone of the Doctor]]. Unfortunately for the new Artificial Hybrid, [[spoiler:Donna's brain is still human enough that she can't handle the entirety of the Doctor's knowledge being copied into it, so he has to wipe her memories of him to save her life, although she is still a hybrid.]]

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* Devilmen of ''Manga/{{Devilman}}'' are humans who fuse with teleporting demons. Some, like protagonist Akira, can switch between human and demon forms at will, but others are stuck with hybrid forms.



* Devilmen of ''Manga/{{Devilman}}'' are humans who fuse with teleporting demons. Some, like protagonist Akira, can switch between human and demon forms at will, but others are stuck with hybrid forms.



* ''VideoGame/StarcraftII'': This is why the Tal'darim willingly serve the BigBad Amon, as they want him to reshape their bodies into the monstrous(ly powerful) Zerg-Protoss hybrids. [[spoiler:Once they learn that this is impossible and all hybrids have to be made from scratch, they defect and join you as the TokenEvilTeammate.]]



* ''VideoGame/StarcraftII'': This is why the Tal'darim willingly serve the BigBad Amon, as they want him to reshape their bodies into the monstrous(ly powerful) Zerg-Protoss hybrids. [[spoiler:Once they learn that this is impossible and all hybrids have to be made from scratch, they defect and join you as the TokenEvilTeammate.]]



* Both ''WesternAnimation/DannyPhantom'' and his ArchEnemy Vlad Plasmius were born human until they were each in accidents that transformed them into Human/Ghost hybrids.
* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'' eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids. Baron Draxum used it to combine their DNA with the mightiest human warrior he could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).



* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'' eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids. Baron Draxum used it to combine their DNA with the mightiest human warrior he could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).
* Both ''WesternAnimation/DannyPhantom'' and his ArchEnemy Vlad Plasmius were born human until they were each in accidents that transformed them into Human/Ghost hybrids.
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* ComicBook/CarolDanvers (a.k.a the current ComicBook/CaptainMarvel) was born a human woman, but eventually her DNA was altered in a way that turned her into a Kree/human hybrid. However, this was later retconned so that her mother was a Kree.

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* ComicBook/CarolDanvers (a.k.a the current ComicBook/CaptainMarvel) Captain Marvel) was born a human woman, but eventually her DNA was altered in a way that turned her into a Kree/human hybrid. However, this was later retconned so that her mother was a Kree.
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* ''Film/CaptainMarvel'' stays true to Carol's original backstory with her being a human who became a Kree hybrid via a blood transfusion.

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* ''Film/CaptainMarvel'' ''Film/CaptainMarvel2019'' stays true to Carol's original backstory with her being a human who became a Kree hybrid via a blood transfusion.
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* Kraka-Tur from ''Videogame/{{Arcanum}}'' is a former human who mutated himself into a DraconicHumanoid by killing Bellerogrim, the last dragon, and using his blood in a magic ritual.
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[[folder:Card Games]]
* ''TabletopGame/MagicTheGathering'':
** This is how most of the sapient Simic hybrids came about. The Simic Combine is very big on shaping and altering one's physical form to suit one's needs, and as a result a great many Simic researchers and theoretically willing subjects who started out as regular elves or humans or merfolk end up becoming chimerical hybrids with the features of several species. A prime example is [[https://scryfall.com/card/rna/195/prime-speaker-vannifar Prime Speaker Vannifar]], who started out as an elf before turning herself into an elf/jellyfish hybrid.
** Crossbreed Labs, in the non-canon set ''Unstable'', explore this trope far more thoroughly than even the Simic do. Their goal is to create a society where everyone can be their true self, which they interpret to mean one where people can have the physical characteristics of whatever cretaure they desire. A typical Crossbreed Labs scientist is a chimera of a good half-dozen animals, any trace of their original self buried beneath their additions and modifications. Their leader, [[https://scryfall.com/card/ust/130/dr-julius-jumblemorph?utm_source=mw_MTGWiki Dr. Julius Jumblemorph]], brings this to its illogical extreme by having a rule that makes him every creature type in the game at once.
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** Typically, driders -- [[SpiderPeople drow/spider centaurs]] -- start out as simply dark elves, before having their legs replaced with a spider's torso.
* ''TabletopGame/{{Pathfinder}}'':
** Driders, like their ''D&D'' progenitors, begin life as dark elves before being turned into elf/spider hybrids. Similarly, oronci are orcs who were transformed into orc/centipede chimeras.
** Areelu Vorlesh, the creator of [[HellGate the Worldwound]], began life as a regular human witch but was transformed into a half-succubus through her service to the demons of the Abyss.
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* Samus from the ''Franchise/{{Metroid}}'' series was spliced with Chozo DNA (specified in the manga to have been from Grey Voice, one of her adoptive fathers) as a child so that she could better survive on the planet Zebes. During the opening of ''VideoGame/MetroidFusion'', she also gets injected with Metroid DNA to help her fight off an infection from the X Parasites. Exactly what percentage of her is still human is never specified.
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* Both ''WesternAnimation/DannyPhantom'' and his ArchEnemy Vlad Plasmius were born human until they were each in accidents that transformed them into Human/Ghost hybrids.
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!!Examples

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\n!!Examples\n!!Examples:






[[folder:Fanfic]]
* In the ''Disney/{{Zootopia}}'' AU [[https://www.fanfiction.net/s/13056744/1/Ouroboros-the-Endless-Cycle Ouroboros: The Endless Cycle]] Judy becomes part fox after she is bitten by a venomous chimera and Nick saves her by transmuting the bitten arm and a few of her internal organs into copies of his own.

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[[folder:Fanfic]]
[[folder:Fan Works]]
* In the ''Disney/{{Zootopia}}'' AU [[https://www.''[[https://www.fanfiction.net/s/13056744/1/Ouroboros-the-Endless-Cycle Ouroboros: The Endless Cycle]] Cycle]]'', Judy becomes part fox after she is bitten by a venomous chimera and Nick saves her by transmuting the bitten arm and a few of her internal organs into copies of his own.



[[folder:Film -- Live-Action]]

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[[folder:Film [[folder:Films -- Live-Action]]



* Played with in ''Series/StarTrekVoyager''. At first it seems as though Seska is a Bajoran (an alien species) but then the doctor finds out that her DNA resembles that of a Cardassian (another alien species). She claims that she had a disease as a kid and got a blood transfusion from a Cardassian, [[spoiler: but it turns out that she's lying and is fully Cardassian]].

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* Played with in ''Series/StarTrekVoyager''. At first it seems as though Seska is a Bajoran (an alien species) but then the doctor finds out that her DNA resembles that of a Cardassian (another alien species). She claims that she had a disease as a kid and got a blood transfusion from a Cardassian, [[spoiler: but [[spoiler:but it turns out that she's lying and is fully Cardassian]].



** ''[[TabletopGame/MagicTheGathering The Guildmaster's Guide To Ravnica]]'' has the Simic Hybrid as a new player character race. They started out as ordinary humans, elves, or vedalken that the Simic Combine experimented on (allegedly with consent of the subject. Allegedly.). The experimentation gives them abilities like being able to breathe underwater, CombatTentacles, or even [[SuperSpit spit acid]].

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** ''[[TabletopGame/MagicTheGathering The Guildmaster's Guide To to Ravnica]]'' has the Simic Hybrid as a new player character race. They started out as ordinary humans, elves, or vedalken that the Simic Combine experimented on (allegedly with consent of the subject. Allegedly.).subject; allegedly). The experimentation gives them abilities like being able to breathe underwater, CombatTentacles, or even [[SuperSpit spit acid]].
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[[folder:Tabletop Games]]
* ''TabletopGame/DungeonsAndDragons'' has had numerous examples over the years:
** Owlbears and [[LandShark Bulettes]] are both monsters that are famously [[AWizardDidIt created by wizards]], mixing bears and giant owls in the case of the former and armadillos and snapping turtles in the case of the latter.
** Many Half-(Whatever) templates in 3rd Edtion were the result of this, like the Half-Elemental.
** ''[[TabletopGame/MagicTheGathering The Guildmaster's Guide To Ravnica]]'' has the Simic Hybrid as a new player character race. They started out as ordinary humans, elves, or vedalken that the Simic Combine experimented on (allegedly with consent of the subject. Allegedly.). The experimentation gives them abilities like being able to breathe underwater, CombatTentacles, or even [[SuperSpit spit acid]].
[[/folder]]

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* Devilmen of ''Manga/{{Devilman}}'' are humans who fuse with teleporting demons. Some, like protagonist Akira, can switch between human and demon forms at will, but others are stuck with hybrid forms.


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* ''VideoGame/ShinMegamiTensei'' is full of these.
** Many humans throughout the franchise have underwent a FusionDance with a demon, from the Chaos Hero of ''VideoGame/ShinMegamiTenseiI'' to the Demonoid population of [[spoiler:Infernal Tokyo in]] ''VideoGame/ShinMegamiTenseiIV''.
** The Demi-Fiend, hero of ''VideoGame/ShinMegamiTenseiIIINocturne'', was an ordinary human transformed into a Fiend by Lucifer, by having a Magatama forcible ingested.
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* Ken Kaneki from ''Manga/TokyoGhoul'' was a normal human being. After an accident that almost killed him, he is given organs from a [[OurGhoulsAreCreepier ghoul]] and becomes a human-ghoul hybrid in the process.

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[[folder:Fanfic]]
* In the ''Disney/{{Zootopia}}'' AU [[https://www.fanfiction.net/s/13056744/1/Ouroboros-the-Endless-Cycle Ouroboros: The Endless Cycle]] Judy becomes part fox after she is bitten by a venomous chimera and Nick saves her by transmuting the bitten arm and a few of her internal organs into copies of his own.
[[/folder]]



* ''Film/CaptainMarvel'' stays true to Carol's original backstory with her being a human who became a Kree hybrid.

to:

* ''Film/CaptainMarvel'' stays true to Carol's original backstory with her being a human who became a Kree hybrid.hybrid via a blood transfusion.
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None


* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'', eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids, rather Baron Draxum used it to combine their DNA with the mightiest human warrior he could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).

to:

* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'', ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'' eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids, rather humanoids. Baron Draxum used it to combine their DNA with the mightiest human warrior he could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).
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* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'', eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids, rather Baron Draxum used it to combine their DNA with the mightiest human warrior they could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).

to:

* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'', eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids, rather Baron Draxum used it to combine their DNA with the mightiest human warrior they he could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).
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None

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* The title characters of ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'', eventually discover [[MutagenicGoo the Ooze]] didn't randomly mutate them into humanoids, rather Baron Draxum used it to combine their DNA with the mightiest human warrior they could find ([[spoiler:Lou Jitsu, who later became Master Splinter]]).
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* OnePiece: The Zoan Devil Fruits can turn their eaters into a hybrid of their original species and the species that the specific Devil Fruit gives. E.g Chopper is a reindeer that ate the Human-Human Fruit and thus can turn partly humanoid, while Lucci is a human that ate the Cat-Cat Fruit.

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* OnePiece: ''Manga/OnePiece'': The Zoan Devil Fruits can turn let their eaters into a hybrid [[{{Animorphism}} turn into]] hybrids of their original species and the species that the specific Devil Fruit gives. E.g Chopper is a reindeer that ate the Human-Human Fruit and thus can turn partly humanoid, while Lucci is a human that ate the Cat-Cat Fruit.
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Most HalfHumanHybrids are created when members of two different species conceive a child together. This trope applies to characters who at birth are fully one species (usually human), but somewhere down the road are turned (deliberately or by accident) into a hybrid between their original species and another one. May or may not occur through magical or scientific means, but in case the subject will often receive HybridPower as a direct result.

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Most HalfHumanHybrids are created when members of two different species conceive a child together.together, [[TrueBreedingHybrid or by descendants thereof]]. This trope applies to characters who at birth are fully one species (usually human), but somewhere down the road are turned (deliberately or by accident) into a hybrid between their original species and another one. May or may not occur through magical or scientific means, but in case the subject will often receive HybridPower as a direct result.
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Created from YKTTW

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Most HalfHumanHybrids are created when members of two different species conceive a child together. This trope applies to characters who at birth are fully one species (usually human), but somewhere down the road are turned (deliberately or by accident) into a hybrid between their original species and another one. May or may not occur through magical or scientific means, but in case the subject will often receive HybridPower as a direct result.

May overlap with BioAugmentation.

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!!Examples

[[foldercontrol]]

[[folder:Anime & Manga]]
* In ''Manga/FullmetalAlchemist'' chimeras are produced by transmuting two individuals of different species together. Human chimeras are heavily illegal, which naturally meant that Father's cabal within the government created several of them as SuperSoldiers.
* OnePiece: The Zoan Devil Fruits can turn their eaters into a hybrid of their original species and the species that the specific Devil Fruit gives. E.g Chopper is a reindeer that ate the Human-Human Fruit and thus can turn partly humanoid, while Lucci is a human that ate the Cat-Cat Fruit.

[[/folder]]

[[folder:Comic Books]]
* ComicBook/CarolDanvers (a.k.a the current ComicBook/CaptainMarvel) was born a human woman, but eventually her DNA was altered in a way that turned her into a Kree/human hybrid. However, this was later retconned so that her mother was a Kree.
* In ''ComicBook/{{Runaways}}'', Victor Mancha is a cyborg created by Ultron. As he grows up, his body is designed to gradually become more organic, so that by the time he becomes an adult, he will be indistinguishable from a mutant and thus easily infiltrate the Avengers in order to betray them.
* Downplayed with ''ComicBook/SpiderMan''. Though Peter Parker is still considered a human, since the spider bite that gave him his powers his genetic code has a very small percentage of spider DNA.
[[/folder]]

[[folder:Film -- Live-Action]]
* ''Film/CaptainMarvel'' stays true to Carol's original backstory with her being a human who became a Kree hybrid.
[[/folder]]

[[folder:Literature]]
* Creator/NnediOkorafor's ''Literature/{{Binti}}'': The StarfishAlien Meduse genetically engineer some of their traits into the title character so she can communicate with them [[spoiler:(including through their HiveMind)]]. This gives her tentacular AlienHair and some of the Meduse's emotions, the latter of which cause her some difficulty since they're much more prone to anger than she.
[[/folder]]

[[folder:Live-Action TV]]
* At the end of the first season of ''Series/Babylon5'', Minbari Ambassador Delenn uses a mysterious biotechnological device to enter a cocoon. At the beginning of the next season, she emerges from it to reveal that she's turned herself into a Minbari/Human hybrid, to be a living bridge between the species.
* Played with in ''Series/StarTrekVoyager''. At first it seems as though Seska is a Bajoran (an alien species) but then the doctor finds out that her DNA resembles that of a Cardassian (another alien species). She claims that she had a disease as a kid and got a blood transfusion from a Cardassian, [[spoiler: but it turns out that she's lying and is fully Cardassian]].
[[/folder]]

[[folder:Video Games]]
* ''VideoGame/StarcraftII'': This is why the Tal'darim willingly serve the BigBad Amon, as they want him to reshape their bodies into the monstrous(ly powerful) Zerg-Protoss hybrids. [[spoiler:Once they learn that this is impossible and all hybrids have to be made from scratch, they defect and join you as the TokenEvilTeammate.]]
[[/folder]]

[[folder:Western Animation]]
* ''WesternAnimation/Ben10Omniverse'' has the Rooters, a rogue Black Op Plumber branch consisting of former humans who became half-alien from experimenting on Kevin when he was in the Null Void. [[spoiler: The HalfHumanHybrid aliens Helen, Manny, Alan, and Pierce]] from ''WesternAnimation/Ben10AlienForce'' are also apparently this, as they were normal humans experimented on by the Rooters and given FakeMemories to make them think they were natural-born hybrids.
* In the last season of ''WesternAnimation/{{Trollhunters}}'', [[spoiler:Jim realizes he cannot win the day in his human form, and reluctantly agrees to undergo a process that will turn him into a human/troll hybrid. At first he enjoys his newfound strength and durability, but then suffers a HeroicBreakdown once he realizes he can't walk in the sun and must effectively abandon his human life forever.]]
[[/folder]]
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