History FourTemperamentEnsemble / AnimeAndManga

* {{Clannad}} has Youhei/Fuuko (sanguine), Kyou (choleric), Tomoyo (melancholic), Nagisa/Ryou/Kotomi (phlegmatic) and Tomoya (leukine).

** Lelouch/Kallen (leukine facade, but actually choleric), Suzaku (melancholic), Rivalz (phlegmatic), Shirley/Milly (sanguine), and Nunally/Nina (leukine).
** [[TheEmpire Britannian]] royalty: TheEmperor/[[LadyOfWar Cornelia]] (choleric), [[ManipulativeBitch Queen Marianne]] (melancholic), [[RebelliousPrincess Euphemia]]/Clovis (sanguine), and [[PrincelyYoungMan Schneizel]] (phlegmatic).

* ''Manga/BlackLagoon'': [[SociopathicHero Revy]] is ''very'' choleric; [[WideEyedIdealist Rock]] is melancholic; [[MissionControl Benny]] is sanguine; and [[BaldBlackLeaderGuy Dutch]] is phlegmatic.

** Ichigo (melancholic), Rukia/Orihime (sanguine), Chad (phlegmatic), Uryu (choleric).
** [[BigBad Aizen]] and his CoDragons: [[KnightTemplar Tousen]] is melancholic, [[TricksterArchetype Gin]] is sanguine, while [[BigBad Aizen]] himself is probably choleric.
** The staff of Urahara's shop: Urahara is phlegmatic, Tessai is sanguine, Jinta is choleric, and Ururu is melancholic.
* The original ''BubblegumCrisis'': Sylia (the stoic leader) is melancholic; Priss (hot-blooded badass) is choleric; Nene (perky and ditzy) is sanguine; and Linna (average Jane) is leukine.
* ''ChronoCrusade'': [[NunTooHoly Rosette]] is sanguine (HotBlooded, cares a lot about others and has a violent temper); [[FailureKnight Chrono]] is phlegmatic (compassionate and nurturing, but easily discouraged); [[HeroicAlbino Azmaria]] is melancholic (a prodigy singer, very caring about others, but insecure and hard on herself); and [[MsFanservice Satella]] is choleric (prideful, determined, and focused on her revenge).

** The Blade Breakers: Tyson (melancholic), Kai (choleric), Ray (phlegmatic), and Max (sanguine).
** White Tigers: Lee (melancholic), Mariah (sanguine), Gary (phlegmatic), and Kevin (choleric).

** Demolition Boys: Tala (melancholic), Spencer (choleric), Ian (sanguine), and Bryan (phlegmatic).

* ''Manga/AzumangaDaioh'': [[GenkiGirl Tomo]] (choleric), [[TheStoic Sakaki]] (melancholic), [[CloudCuckoolander Osaka]] (leukine),[[CheerfulChild Chiyo-chan]] (sanguine), and [[StraightMan Yomi]] (phlegmatic).
* Shuya's closest friends before the program begins in ''Manga/BattleRoyale'' fit into this. [[WideEyedIdealist Shuya]] is sanguine; [[PlayfulHacker Shinji]] is choleric; [[MartialPacifist Hiroki]] is melancholic; and although Yoshitoki is killed before we get to learn much about him, he seems to be leukine.

* The eponymous band in ''Manga/{{Beck}}'' fits this even better than the FiveManBand pattern: Koyuki (leukine), Chiba (choleric), Taira (melancholic;), and Saku (sanguine), and Ryusuke (phlegmatic).

* ''Manga/AzumangaDaioh'': [[CheerfulChild Chiyo-chan]] (sanguine), [[GenkiGirl Tomo]] (choleric), [[TheStoic Sakaki]] (melancholic), [[StraightMan Yomi]] (phlegmatic), and [[CloudCuckoolander Osaka]] (leukine).

* The girls in the dorm from ''Manga/AiKora'' fit into this: Tsubame is sanguine, Sakurako is choleric, Yukari is melancholic, and Kirino is (for the most part) phlegmatic.

* The Wammy's House residents from ''Manga/DeathNote'': Matt (sanguine), Mello (choleric), Near (phlegmatic), and L (melancholic).

* In ''Manga/FairyTail'', [[TheHero Natsu]] and [[TheSmartGuy Happy]] (sanguine), [[TheChick Lucy]] (sanguine), [[TheLancer Gray]] (phlegmatic), and [[TheBigGuy Erza]] (choleric).

* In ''Manga/FairyTail'', [[TheHero Natsu]] (melancholic), [[TheChick Lucy]] (sanguine), [[TheLancer Gray]] (phlegmatic), and [[TheBigGuy Erza]] (choleric).

** The Blade Breakers: Tyson (melancholic), Kai (choleric), Ray (leukine), and Max (sanguine).
** White Tigers: Lee (melancholic), Mariah (sanguine), Gary (leukine), and Kevin (choleric).
** All Starz: Michael (sanguine), Eddie (leukine), Steven (choleric) and Emily (melancholic).
** The Majestics: Robert (melancholic), Johnny (choleric), Oliver (leukine), and Enrique (sanguine).
** Demolition Boys: Tala (melancholic), Spencer (choleric), Ian (sanguine), and Bryan (leukine).
* ''Manga/BlackLagoon'': [[SociopathicHero Revy]] is ''very'' choleric; [[WideEyedIdealist Rock]] is melancholic; [[MissionControl Benny]] is sanguine; and [[BaldBlackLeaderGuy Dutch]] is leukine.

** Ichigo (melancholic), Rukia/Orihime (sanguine), Chad (leukine), Uryu (choleric).

* The original ''BubblegumCrisis'': Sylia (the stoic leader) is melancholic; Priss (hot-blooded badass) is choleric; Nene (perky and ditzy) is sanguine; and Linna (average Jane) is neutral phlegmatic.
* ''ChronoCrusade'': [[NunTooHoly Rosette]] is sanguine (HotBlooded, cares a lot about others and has a violent temper); [[FailureKnight Chrono]] is leukine (compassionate and nurturing, but easily discouraged); [[HeroicAlbino Azmaria]] is melancholic (a prodigy singer, very caring about others, but insecure and hard on herself); and [[MsFanservice Satella]] is choleric (prideful, determined, and focused on her revenge).
* {{Clannad}} has Youhei/Fuuko (sanguine), Kyou (choleric), Tomoyo (melancholic), Nagisa/Ryou/Kotomi (leukine) and Tomoya (phlegmatic).

** Lelouch/Kallen (neutral phlegmatic facade, but actually choleric), Suzaku (melancholic), Rivalz (leukine), Shirley/Milly (sanguine), and Nunally/Nina (phlegmatic).
** [[TheEmpire Britannian]] royalty: TheEmperor/[[LadyOfWar Cornelia]] (choleric), [[ManipulativeBitch Queen Marianne]] (melancholic), [[RebelliousPrincess Euphemia]]/Clovis (sanguine), and [[PrincelyYoungMan Schneizel]] (leukine).

** Space-case Ed (sanguine), hot-tempered Faye (choleric), high-strung Jet (leukine), and Spike (melancholic through and through).
* The Wammy's House residents from ''Manga/DeathNote'': Matt (sanguine), Mello (choleric), Near (leukine), and L (melancholic).

** Tai (choleric), TK (sanguine), Matt (melancholic), Izzy (leukine), and Joe (phlegmatic).
** Also the four Dark Masters fit this trope. Piedmon is choleric, being the leading element. The cold and calculating EvilGenius Machinedramon is melancholic. Metalseadramon is leukine, being pragmatic but also a good boss towards his minions as long as they don't fail him. Puppetmon, with his HotBlooded PsychopathicManchild demeanor, is sanguine.
** ''Anime/DigimonTamers'': [[TheHeart Takato]] (leukine), [[ControlFreak Henry]] (melancholic), [[ArrogantKungfuGuy Rika]] (choleric), and [[StepfordSmiler Jeri]] (sanguine).
** ''Anime/DigimonSavers'': [[HotBlooded Marcus]] (choleric), [[TeenGenius Thomas]] (melancholic), [[WildChild Keenan]] (sanguine), and [[FauxActionGirl Yoshi]] (leukine/phlegmatic). Even the original expedition could fit: [[GeniusBruiser Spencer]] (choleric), [[BigBad Kurata]] (melancholic), [[CoolOldGuy Yushima]] (sanguine), and the [[GoodParents Criers]] (leukine).
* The main girls of ''Manga/DoujinWork''. Sora (sanguine), Najimi (choleric), Kaneru (melancholic), and Tsuyuri (leukine).
* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku (sanguine), Piccolo (melancholic), Krillin (leukine), Vegeta (choleric), and Gohan (phlegmatic).
* ''Manga/ElfenLied'': Lucy/Kaede (melancholic), Kohta (sanguine), Nana (leukine), Yuka (choleric), and Mayu (phlegmatic).
* Although there are six main characters, this can work for ''Et Cetera'', too: Mingchao (sanguine), Fino (choleric), Benkate is (melancholic), Baskerville (leukine), Alternate (random phlegmatic), and Yaghi (neutral phlegmatic). Mingchao can also be seen as melancholic while Benkate is sanguine.

** Kyoshin: Mizumachi (sanguine), the Hiroshis (choleric), Kakei (melancholic), and Kobanzame (leukine).
* In ''Manga/FairyTail'', [[TheHero Natsu]] (melancholic), [[TheChick Lucy]] (sanguine), [[TheLancer Gray]] (leukine), and [[TheBigGuy Erza]] (choleric).

** Of the main protagonists: Ed (choleric), Alphonse (phlegmatic), and Winry (sanguine). Of the soldiers: Roy (melancholic), Riza (leukine), Armstrong (choleric), and Hughes (sanguine).
** Roy's male subordinates: Jean Havoc (sanguine), Heymans Breda (choleric), Vato Falman (melancholic), and Kain Fuery (leukine).
** ([[Anime/FullmetalAlchemist 2003 Anime]]) The homunculi: Wrath & Gluttony (sanguine), Envy & Pride (choleric), Lust & Sloth (melancholic), and Greed (leukine).
* ''GhostInTheShellStandAloneComplex'': Motoko Kusanagi (melancholic), Batou (sanguine), Togusa (leukine), and Chief Aramaki (choleric).
* The Gundam Meisters in ''{{Gundam 00}}'' fit this: Setsuna (leukine), Lockon (sanguine), Tieria (choleric), and Allelujah (melancholic).

** Athrun (melancholic), Yzak (choleric), Dearka (leukine), and Nicol (phlegmatic). The four main leads as well with Kira and Athrun being leukine and melancholic, respectively, Cagali being choleric and Lacus being sanguine.
** The Minerva pilots in ''GundamSeedDestiny'' possess two temparents: Shinn (both sanguine and melancholic), Athrun (choleric and melancholic), Ray (both melancholic and leukine), and Lunamaria (sanguine and leukine).
* ''GundamWing'': Heero Yuy (melancholic), Duo Maxwell (sanguine), Trowa Barton and Quatre Winner (leukine, phlegmatic), and Chang Wu Fei (choleric).
* The Shuffle Alliance from ''Anime/MobileFighterGGundam'': Domon Kasshu (choleric), Chibodee Crockett and Sai Saici (sanguine), George [=De=]Sand (melancholic), and Argo Gulskii (leukine).
* ''GurrenLagann'': (Early episodes) Simon (melancholic), Kamina (sanguine), Yoko (choleric), and Leeron (leukine).
* The four main boxers from ''HajimeNoIppo'' fit this well: Ippo (sanguine), Takamura (both choleric and sanguine), Aoki (melancholic), and Kimura (leukine).

* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku (sanguine), Piccolo (melancholic), Kryllin (leukine), Vegeta (choleric), and Gohan (phlegmatic).

* ''Manga/AzumangaDaioh'': [[CheerfulChild Chiyo-chan]] (sanguine), [[GenkiGirl Tomo]] (choleric), [[TheStoic Sakaki]] (melancholic), [[StraightMan Yomi]] (leukine), and [[CloudCuckoolander Osaka]] (phlegmatic).

* ''Manga/AzumangaDaioh'': [[CheerfulChild Chiyo-chan]] is sanguine, [[GenkiGirl Tomo]] is choleric, [[TheStoic Sakaki]] is melancholic, [[StraightMan Yomi]] is leukine, and [[CloudCuckoolander Osaka]] is phlegmatic.

* The eponymous band in ''Manga/{{Beck}}'' fits this even better than the FiveManBand pattern: Koyuki is leukine; Ryusuke is phlegmatic; Chiba is choleric; Taira is melancholic; and Saku is sanguine.

** Ichigo (melancholic), Rukia/Orihime (sanguine), Chad (phegmatic), Uryu (choleric).

* The original ''BubblegumCrisis'': Sylia (the stoic leader) is Melancholic, Priss (hot-blooded badass) is Choleric, Nene (perky and ditzy) is Sanguine, and Linna (average Jane) is Phlegmatic II.
* ''ChronoCrusade'': [[NunTooHoly Rosette]] is sanguine (HotBlooded, cares a lot about others and has a violent temper), [[FailureKnight Chrono]] is phlegmatic (compassionate and nurturing, but easily discouraged), [[HeroicAlbino Azmaria]] is melancholic (a prodigy singer, very caring about others, but insecure and hard on herself) and [[MsFanservice Satella]] is choleric (prideful, determined, and focused on her revenge).
* {{Clannad}} has Youhei/Fuuko as sanguine, Kyou as choleric, Tomoyo as melancholic, Nagisa/Ryou/Kotomi as phlegmatic and Tomoya as leukine.

** Lelouch/Kallen (phlegmatic II facade but actually choleric), Suzaku (melancholic), Nunally/Nina (Leukine), Rivalz (phlegmatic), and Shirley/Milly (sanguine).
** [[TheEmpire Britannian]] royalty: TheEmperor/[[LadyOfWar Cornelia]] (choleric), [[ManipulativeBitch Queen Marianne]] (Melancholic), [[RebelliousPrincess Euphemia]]/Clovis (sanguine), and [[PrincelyYoungMan Schneizel]] (phlegmatic).

** Ed is Sanguine (the space case variety), Faye is hot-tempered Choleric, Jet is high-strung Phlegmatic, and Spike is Melancholic through and through.
* The Wammy's House residents from ''Manga/DeathNote''. Matt is sanguine; Mello is choleric; Near is leukine; and L is melancholic.

** Tai is choleric; TK is sanguine; Matt is melancholic; Izzy is leukine; and Joe is phlegmatic.

** ''Anime/DigimonTamers'': [[TheHeart Takato]] is leukine; [[ControlFreak Henry]] is melancholic; [[ArrogantKungfuGuy Rika]] is choleric; and [[StepfordSmiler Jeri]] is sanguine.
** ''Anime/DigimonSavers'': [[HotBlooded Marcus]] is choleric; [[TeenGenius Thomas]] is melancholic; [[WildChild Keenan]] is sanguine; and [[FauxActionGirl Yoshi]] is leukine/phlegmatic. Even the original expedition could fit: [[GeniusBruiser Spencer]] is choleric; [[BigBad Kurata]] is melancholic, [[CoolOldGuy Yushima]] is sanguine, the [[GoodParents Criers]] are leukine.
* The main girls of ''Manga/DoujinWork''. Sora is sanguine; Najimi is choleric; Kaneru is melancholic; and Tsuyuri is phlegmatic.
* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku is sanguine, Piccolo is melancholic, Krillin is phlegmatic, Vegeta is choleric, and Gohan is leukine.
* ''Manga/ElfenLied'': Lucy/Kaede is melancholic, Kohta is sanguine, Mayu is leukine, Nana is phlegmatic and Yuka is choleric.
* Although there are six main characters, this can work for ''Et Cetera'', too. Mingchao is sanguine, Fino is choleric, Benkate is melancholic, Baskerville is phlegmatic, Alternate is leukine, and Yaghi is 5th temperament phlegmatic. Mingchao can also be seen as melancholic while Benkate is sanguine.

** Kyoshin: Mizumachi is sanguine, the Hiroshis are choleric, Kakei is melancholic, and Kobanzame is phlemetic.
* In ''Manga/FairyTail'', [[TheHero Natsu]] is melancholic, [[TheChick Lucy]] is sanguine, [[TheLancer Gray]] is phlegmatic Type I and [[TheBigGuy Erza]] is choleric.

** Of the main protagonists: Ed is Choleric, Alphonse is phlegmatic, and Winry is sanguine. Of the soldiers: Roy is Melancholic, Riza is Phlegmatic, Armstrong is Choleric, and Hughes is Sanguine.
** Roy's male subordinates: Jean Havoc is sanguine, Heymans Breda is choleric, Vato Falman is melancholic and Kain Fuery is phlegmatic.
** ([[Anime/FullmetalAlchemist 2003 Anime]]) The homunculi: Wrath & Gluttony are Sanguine, Envy & Pride are Choleric, Lust & Sloth are Melancholic and Greed is Phlegmatic.
* ''GhostInTheShellStandAloneComplex'': Motoko Kusanagi is melancholic, Batou is sanguine, Togusa is phlegmatic and Chief Aramaki is choleric.
* The Gundam Meisters in ''{{Gundam 00}}'' fit this: Setsuna is phlegmatic, Lockon is sanguine, Tieria is choleric and Allelujah is melancholic.

** Athrun is melancholic, Yzak is choleric, Dearka is phlegmatic and Nicol is leukine. The four main leads as well with Kira and Athrun being phlegmatic and melancholic, respectively, Cagali being choleric and Lacus being sanguine.
** The Minerva pilots in ''GundamSeedDestiny'' possess two temparents: Shinn is both sanguine and melancholic, Athrun is choleric and melancholic, Ray is both melancholic and phlegmatic and Lunamaria is sanguine and phlegmatic.
* ''GundamWing'': Heero Yuy is melancholic, Duo Maxwell is sanguine, Trowa Barton and Quatre Winner are phlegmatic and Chang Wu Fei is choleric.
* The Shuffle Alliance from ''Anime/MobileFighterGGundam'': Domon Kasshu is Choleric, Chibodee Crockett and Sai Saici are Sanguine, George [=De=]Sand is Melancholic and Argo Gulskii is Phlegmatic.
* ''GurrenLagann'': (Early episodes) Simon is melancholic, Kamina is sanguine, Yoko is choleric and Leeron is phlegmatic.
* The four main boxers from ''HajimeNoIppo'' fit this well, Ippo is Sanguine, Takamura is both Choleric and Sanguine, Aoki is Melancholic and Kimura is Phlegmatic.
* ''HunterXHunter'': Gon is sanguine, Killua is choleric, Kurapika is melancholic, and Leorio is phlegmatic.
* InazumaEleven has the managers fit into the arrangement perfectly; Natsumi is choleric, Haruna is sanguine, Aki is phlegmatic and Fuyuka is melancolic.
* ''{{K-on}}!'' has a slight variation: Yui is sanguine/phlegmatic, Mio is Leukine, Ritsu is ''"sangoleric"'' and Mugi is melancholic.
* ''[[KamenRiderDenO KamenRider Den-O's]]'' four Imagin: Ryutaros is sanguine, Momotaros is choleric, Urataros is melancholic and Kintaros is phlegmatic.
* The main cast of ''Manga/KatekyoHitmanReborn'': Tsuna is phlegmatic, Gokudera is choleric, Yamamoto, Lambo and Ryohei are sanguine, Hibari is melanchonic and Mukuro is ''"sangoleric"''. Chrome is Leukine.
* ''KeroroGunsou'' follows the 5-humor style: Giroro is choleric, Dororo is melancholic, Kururu is phlegmatic, Tamama is sanguine, and Keroro is Leukine.
* ''Anime/LuckyStar:'' Konata is Sanguine, Kagami is Choleric, Miyuki is Melancholic, and Tsukasa is Leukine (None of the main characters qualify as either definition of Phlegmatic).

** GenkiGirl [[ThePollyanna Pollyanna]] Subaru is Sanguine, natural leader (former) {{Tsundere}} Teana is Choleric, knight-in-training Erio is Melancholic, and Caro is Phlegmatic. The last two's personalities actually caused a bit of family drama for their also Melancohlic adopted mother in the second ''[[AudioAdaptation StrikerS Sound Stage]]'', since [[NonverbalMiscommunication their combined introvertedness caused some communication problems]].
** Similarly, Hayate's four knights. Vita is choleric, Signum is melancholic, Zafira is phlegmatic, and Shamal is sanguine.
** After StrikerS, the four Combat Cyborgs [[spoiler:who were adopted into the Nakajima family]] are this, with Nove being choleric, Dieci being melancholic, Cinque being phlegmatic and [[GenkiGirl Wendi]] being sanguine.
* ''MagicalPokaan'''s four girls match. Yuuma is sanguine, Pachira is choleric, Aiko is melancholic and Liru is phlegmatic.
* Kozu's five personalities in ''{{Mahoraba}}'': Kozue is sanguine (so is Nanako, because she's a kid version of Kozue), Saki is choleric, Chiyuri is phlegmatic, Natsume is melancholic.
* ''MahouSenseiNegima'':
** Asuna (choleric), Setsuna (melancholic), Kuu (sanguine), Yue (phlegmatic), Nodoka (Leukine) and Konoka (Phlegmatic II).
** The four sports stars include Makie (sanguine), Yuna (choleric), Ako (melancholic) and Akira (phlegmatic).
* ''Manga/{{Monster}}'': Tenma is melancholic, Johan is phlegmatic, Anna/Nina is Sanguine, Eva is choleric.
* Team Kakashi in ''Manga/{{Naruto}}'': Naruto is sanguine, Sakura is choleric, Sasuke is melancholic. Kakashi was also melancholic, as he was the "Sasuke" of his own three-man team as a kid, although he's currently phlegmatic. His partners (the "Naruto" and the "Sakura", respectively) were sanguine Obito and Leukine Rin.
* A good example is ''Anime/NeonGenesisEvangelion''. Shinji/Rei are phlegmatic, Asuka/Mari are choleric, Misato/Kaji are sanguine, and Ritsuko/Gendo are melancholic. You could actually also fit in Kaworu here as leukine since he seemingly has absolutely no internal turmoil whatsoever at all. Of course, he only appears once (and when he does appear, Asuka is unconscious) so he doesn't completely count.
* ''Anime/NerimaDaikonBrothers'': Hideki is choleric, Mako is sanguine, Ichiro is melancholic, and TeamPet Pandaikon is phlegmatic.
* ''OnePiece'''s main male cast. Luffy is Sanguine, Zoro is Choleric, Sanji is Phlegmatic, Usopp is Melancholic, and Tony Tony Chopper is Leukine.
** Oddly enough is that the remanining members of the crew fit the bill perfectly: Nami is choleric, Robin is phlegmatic, Franky is sanguine and Brook is melancholic.
* Although everyone in ''OokikuFurikabutte'' gets their turn to shine, the story tends to focus on four core members of the baseball team. [[CloudCuckoolander Tajima]] is sanguine, [[TheCaptain Hanai]] is choleric, [[TheStrategist Abe]] is melancholic, and [[FragileFlower Mihashi]] is phlegmatic.

** Pikachu is melancholic, Bulbasaur was choleric, Squirtle was sanguine, and Charmander/Charmeleon/Charizard was phlegmatic.
** ''Original Series'' - Ash is the melancholic, Pikachu is the sanguine, Misty is the choleric, and Brock/Tracey is the phlegmatic.
** ''Advanced Generation'' - Ash is the choleric, May is the sanguine, Max is the melancholic, and Brock is the phlegmatic (Type II). If you count Pikachu here, he becomes the leukine.
** ''Diamond and Pearl'' - Ash is the Choleric, Dawn is the Sanguine, Pikachu is the Phlegmatic, and Brock is the Melancholic.
** ''Best Wishes'' - Ash is the Choleric, Pikachu is the Phlegmatic, Iris is the Sanguine, and Cilan is the Melancholic.
* PrincessTutu has Ahiru as sanguine, Fakir as choleric, Rue as melancholic and Mytho as phlegmatic
* The four ARMS teenagers in ProjectARMS. Ryo is Phlegmatic, Hayato is Choleric, Takeshi is Sanguine, and Kei is Melancholic.
* ''Anime/PuellaMagiMadokaMagica'': Sayaka is Sanguine, Kyoko is Choleric, Homura is Melancholic, Mami is Phlegmatic type I, and Madoka is Leukine.
* ''RanmaOneHalf'': Despite not always acting as a group, Ranma is sanguine, Akane is choleric, Ryoga is melancholic and Genma is phlegmatic.
* For the main cast of Manga/RurouniKenshin, [[TheMessiah Kenshin]] is phlegmatic, [[HotBlooded Sano]] and [[BrattyHalfPint Yahiko]] are choleric, [[PluckyGirl Kaoru]] is sanguine, and [[TheMedic Megumi]] is melancholic.
* ''Anime/SaberMarionetteJ'': Lime is sanguine, Cherry is melancholic, Bloodberry is choleric and Otaru is phlegmatic.

** The Outer Senshi: Setsuna/Sailor Pluto is Sanguine, Haruka/Sailor Uranus is Choleric, Michiru/Sailor Neptune is Melancholic , and Hotaru/Sailor Saturn is Phlegmatic.
** The Inner Senshi: Minako/Sailor Venus is Sanguine, Rei/Sailor Mars is Choleric (in the anime), Ami/Sailor Mercury is Melancholic, and Makoto/Sailor Jupiter is Phlegmatic.
* From ''SaintBeast'' [[KidAppealCharacter Gai]] is sanguine, [[TheHero Goh]] is choleric, [[TheChick Rei]] is melancholic and [[TheLancer Shin]] is phlegmatic.
* ''{{Saiyuki}}'' also has two. For the Sanzo party, Goku is sanguine, Sanzo is choleric, Hakkai is melancholic, and Gojyo is phlegmatic. For Kougaiji's group, Lirin is sanguine and Kougaiji is choleric. Yaone and Dokugakuji switch off between melancholic and phlegmatic, although neither of them are actually lazy.
* ''{{Samurai Champloo}}'': Mugen is sanguine, Jin is melancholic and Fuu is choleric.

** Kafuka is sanguine, Nami is phlegmatic, Chiri is choleric, and Itoshiki-sensei is melancholic.
** Also in the show, Haga is sanguine, Jun is phlegmatic, Kuniya is choleric and Aoyama is melancholic.
** Maria is sanguine, Harumi/Kiri/Matoi/Other relatively sane characters are phlegmatic, Kaere is choleric, Abiru is melancholic.

** All Starz: Michael (sanguine), Eddie (leukine), Steven is choleric and Emily is melancholic.
** The Majestics: Robert is melancholic, Johnny is choleric, Oliver is phlegmatic and Enrique is sanguine.
** Demolition Boys: Tala is melancholic, Spencer is choleric, Ian is sanguine and Bryan is phlegmatic.
* ''Manga/BlackLagoon'': [[SociopathicHero Revy]] is ''very'' choleric, [[WideEyedIdealist Rock]] is melancholic, [[MissionControl Benny]] is sanguine, and [[BaldBlackLeaderGuy Dutch]] is phlegmatic.

* ''Manga/AzumangaDaioh'': [[CheerfulChild Chiyo-chan]] is sanguine, [[GenkiGirl Tomo]] is choleric, [[TheStoic Sakaki]] is melancholic, [[StraightMan Yomi]] is phlegmatic, and [[CloudCuckoolander Osaka]] is leukine.
* Shuya's closest friends before the program begins in ''Manga/BattleRoyale'' fit into this. [[WideEyedIdealist Shuya]] is sanguine, [[PlayfulHacker Shinji]] is choleric, [[MartialPacifist Hiroki]] is melancholic and although Yoshitoki is killed before we get to learn much about him, he seems to be phlegmatic.
* The eponymous band in ''Manga/{{Beck}}'' fits this even better than the FiveManBand pattern: Koyuki is leukine, Ryusuke is phlegmatic, Chiba is choleric, Taira is melancholic and Saku is sanguine.

** The Blade Breakers: Tyson-Melancholic, Kai-Choleric, Ray-Phlegmatic, and Max-Sanguine.
** White Tigers: Lee is melancholic, Mariah is sanguine, Gary is phlegmatic and Kevin is choleric.
** All Starz: Michael is sanguine, Eddie is phlegmatic, Steven is choleric and Emily is melancholic.

* The Wammy's House residents from ''Manga/DeathNote''. Matt is Sanguine, Mello is Choleric, Near is Phelgmatic and L is Melancholic.

** Tai is Choleric, TK is sanguine, Matt is melancholic, Izzy is Phlegmatic, and Joe is Leukine.
** Also the four Dark Masters fit this trope. Piedmon is choleric, being the leading element. The cold and calculating EvilGenius Machinedramon is melancholic. Metalseadramon is phlegmatic, being pragmatic but also a good boss towards his minions as long as they don't fail him. Puppetmon, with his HotBlooded PsychopathicManchild demeanor, is sanguine.
** ''Anime/DigimonTamers'': [[TheHeart Takato]] is phlegmatic, [[ControlFreak Henry]] is melancholic, [[ArrogantKungfuGuy Rika]] is choleric and [[StepfordSmiler Jeri]] is sanguine.
** ''Anime/DigimonSavers'': [[HotBlooded Marcus]] is choleric, [[TeenGenius Thomas]] is melancholic, [[WildChild Keenan]] is sanguine, and [[FauxActionGirl Yoshi]] is leukine/phlegmatic. Even the original expedition could fit: [[GeniusBruiser Spencer]] is choleric, [[BigBad Kurata]] is melancholic, [[CoolOldGuy Yushima]] is sanguine, the [[GoodParents Criers]] are leukine.
* The main girls of ''Manga/DoujinWork''. Sora is sanguine, Najimi is choleric, Kaneru is melancholic and Tsuyuri is phlegmatic.

* The main cast of ''Manga/KatekyoHitmanReborn'': Tsuna is phlegmatic, Gokudera is choleric, Yamamoto, Lambo and Ryohei are sanguine, Hibari is melanchonic and Mukuro is choleric/sanguine. Chrome is Leukine.

* ''{{K-on}}!'' has a slight variation: Yui is sanguine/phlegmatic, Mio is Leukine, Ritsu is sanguine/choleric and Mugi is melancholic.

* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku is melancholic, Piccolo is phlegmatic, Krillin is sanguine, Vegeta is choleric, and Gohan is leukine.

* ''HeartcatchPrettyCure'': [[ShrinkingViolet Tsubomi]] is Leukine, [[GenkiGirl Erika]] is sanguine, [[StudentCouncilPresident Itsuki]] is phlegmatic (but like Karen, not lazy by any stretch), and [[BrokenBird Yuri]] is melancholic.

* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku is sanguine, Piccolo is melancholic, Krillin is phlegmatic, Vegeta is choleric, and Gohan is leukine.

* In ''Manga/FairyTail'', [[TheHero Natsu]] is sanguine, [[TheChick Lucy]] is melancholic, [[TheLancer Gray]] is phlegmatic Type I and [[TheBigGuy Erza]] is choleric.

* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku is melancholic, Piccolo is phlegmatic, Krillin is sanguine, Vegeta is choleric, and Gohan is leukine.

** The Blade Breakers: Tyson-Choleric, Kai-Phlegmatic, Ray-Melancholic, and Max-Sanguine.

* The Z-fighters from ''Manga/DragonBall'' ([[MyFriendsAndZoidberg excluding Tenshinhan, Yamcha, and Chiaotzu]]): Goku is sanguine, Piccolo is melancholic, Krillin is phlegmatic, Vegeta is choleric, and Gohan is leukine.

** Pikachu is choleric, Bulbasaur was melancholic, Squirtle was sanguine, and Charmander/Charmeleon/Charizard was phlegmatic.
** ''Original Series'' - Ash is the choleric, Pikachu is the sanguine, Misty is the phlegmatic, and Brock/Tracey is the melancholic.

* The Shuffle Alliance from ''Anime/MobileFighterGGundam'': Domon Kasshu is Choleric, Chibodee Crockett and Sai Saici are Sanguine, George =[De]=Sand is Melancholic and Argo Gulskii is Phlegmatic.

* The Shuffle Alliance from ''Anime/MobileFighterGGundam'': Domon is Choleric, Chibodee and Sai Saici are Sanguine, George is Melancholic and Argo is Phlegmatic.

* If you divide the cast in ''FullmetalAlchemist'' into different groups, it's easy to see this:

** (2003 Anime) The homunculi: Wrath & Gluttony are Sanguine, Envy & Pride are Choleric, Lust & Sloth are Melancholic and Greed is Phlegmatic.