History AndIMustScream / MarvelUniverse

* ''Film/AntManAndTheWasp'':
** Janet van Dyne shrunk between molecules to disarm a bomb headed for Washington, DC. However, in doing so she got stuck in the [[AcidTripDimension Quantum Realm]], alone, for ''thirty years'', with her husband and daughter convinced she was dead.
** [[spoiler: In TheStinger, Scott is sent into the Quantum Realm in order to get healing particles for Ghost. However, before Hank, Hope and Janet can pull him back out, they're ''turned to dust'' by [[Film/AvengersInfinityWar Thanos's finger snap]], leaving Scott alone and [[HistoryRepeats stuck in the Quantum Realm]] as he screams for help over the radio. But unlike with Janet, the only people who even ''know'' where he is and how to bring him back are gone, and Scott not coming home means he's chalked up as another of Thanos's victims, meaning no-one will look for him.]]
*** [[spoiler: ''[[Film/AvengersEndgame Endgame]]'' reveals that luckily the wait was only five hours for Scott...but five years have passed in the real world and he was only freed because of a ''rat'' stepping on the right sequence of buttons. It's still pretty chilling that it was only through sheer random chance that he wasn't stuck for any longer.]]
* ''Film/DoctorStrange2016''
** [[spoiler:Through the Eye of Agamatto, Strange sets a time loop on the moment where he arrives to bargain with Dormammu. [[GroundhogDayLoop It repeats over and over, no matter how many times Strange is killed]] -- he even says "you are my prisoner". Strange, by the end, is willing to endure an eternity of torture in Dormammu's hands for the sake of the Earth. Eventually, Dormammu gets tired of being trapped and agrees to withdraw from Earth.]]
** This scene is actually pay-off to a [[{{Foreshadowing}} severe warning Karl gives Strange about using the Eye earlier in the film.]] He mentions that using it irresponsibly can lead to the user reliving the same moment over and over without end or being removed from existence outright. We'll take the latter, thanks.
** [[spoiler:One of the conditions of Strange's bargain is that Dormammu leaves Earth for good, and takes Kaecilius and his Zealots with him to the dark dimension. Strange tells them they're getting eternal life as they wanted, and [[BeCarefulWhatYouWishFor they're not gonna like it]].]]

* In ''Film/IronMan2'', Rhodey is trapped inside the War Machine armor with no control over it, no way out and he is forced to try and kill his best friend. The look he gives Tony when Natasha finally reboots the armor remotely says it all.

** In ''ComicBook/TheAmazingSpiderMan1963'' #230, This happened to the ComicBook/{{Juggernaut|MarvelComics}} when Spider-Man buried him in tons of concrete.

* ''ComicBook/{{Daredevil}}'': The ultimate fate of Bullseye In ''ComicBook/DaredevilMarkWaid'' #27. After a demonically possessed Daredevil killed Bullseye in ''ComicBook/{{Shadowland}}'', Lady Bullseye manages to resurrect him, but he's completely paralyzed, has lost all his senses except his eyesight, and needs to be placed in an iron lung. Bullseye comes up with a rather elaborate plot to torment Daredevil and ultimately kill him. He fails and in the process loses his sense of sight. One of the most vicious, psychotic, and frightening villains in the Marvel Universe is now, in the words of Daredevil, "a living brain in a flesh and bone coffin."

** In an annual written by Warren Ellis, the Scarecrow (not the Batman villain) creates a haunted house sown together with live human beings. Upon defeating him, [[spoiler:Ghost Rider breaks every bone in the Scarecrow's body, then twists every bone in the Scarecrow's body so the bones will not heal properly, thus leaving the Scarecrow as a permanently paralyzed and disjointed mess.]] He later got better.
** The Deacon is paralyzed in the last issue of ''ComicBook/{{Ghost Rider}}s: Heaven's On Fire''. Total paralysis. He'll never move again. And he's going to spend his days in prison with the All-New Orb. Surely, this is a fate worse than death. This was actually ''intended'' as the ultimate punishment - rather than killing him and having him join his master Zadkiel, having him suffer through a pathetic life.

* ''ComicBook/DistrictX'': During the ''ComicBook/HouseOfM'' tie-in, two of Kaufman's henchmen are walking inside a warehouse belonging to one of Kaufman's deposed drug gang rivals. One of the henchmen is talking about the deposed drug lord. The other henchman says, "What a terrible way to end your life." To which the other henchman replies "Who said anything about him being dead?" [[spoiler:He is being suspended on top of the warehouse by chains, and later gets horrific revenge on Kaufman in a method that is left to the reader's imagination]].
* ''ComicBook/NewMutants'': How do you deal with a sadistic person that can control people with her voice? [[spoiler: Simple. Use dark magic to completely remove her mouth, reducing her to a broken, weeping mess.]] Do not mess with Doug Ramsey. Seriously.
* ''ComicBook/{{Ruins}}'': Taking place in an alternate Marvel Universe, the Gamma Bomb that was supposed to turn Bruce Banner into [[ComicBook/TheIncredibleHulk the Hulk]] instead turned him into [[spoiler:a huge mass of gigantic tumors and horrific maiming all over the body, which Rick Jones claims is still being kept alive in a CIA facility]].

** In ''ComicBook/TheAmazingSpiderMan1963'' #430–431, ComicBook/{{Carnage}} was turned by the ComicBook/SilverSurfer into a statue that still lives and thinks, but cannot move, in order to arrest the rapid encroachment of stomach cancer into his body without the symbiote.

* ''ComicBook/SpiderMan'': This happened to the Juggernaut at the end of ''ComicBook/TheAmazingSpiderMan1963'' #230, when ComicBook/SpiderMan buried him in tons of concrete.
* ComicBook/{{Carnage}}, a rogue of Comicbook/SpiderMan, was turned by the Silver Surfer into a statue that still lives and thinks, but cannot move, in order to arrest the rapid encroachment of stomach cancer into his body without the symbiote.
* Happens to ''ComicBook/{{Daredevil}}'' archenemy [[spoiler:Bullseye. Let's see...a demonically possessed Daredevil kills the guy in the ''Shadowlands'' story arc. Lady Bullseye manages to resurrect him, but he's completely paralyzed, has lost all his senses except his eyesight, and needs to be placed in an iron lung. Bullseye comes up with a rather elaborate plot to torment Daredevil and ultimately kill him. He fails and in the process loses his sense of sight. One of the most vicious, psychotic, and frightening villains in the Marvel Universe is now, in the words of Daredevil, "a living brain in a flesh and bone coffin."]]
* Played for laughs with throwaway ''ComicBook/{{Deadpool}}'' villain The White Man. The White Man has Mandarin tech that allows his cane to turn people into stone; a fate he is subjected to when Deadpool, Luke Cage, and Iron Fist fight him in the 70's. He is unfrozen in the present day (Deadpool loves to mock comic book time) where it's revealed he was conscious and fully aware of his surroundings the entire time. He attempts to freeze Cage and Iron Fist and dump them in the ocean, but Iron Fist's students kick him in the balls, freeze him in a pose holding his crotch, and accidentally knock him overboard. The heroes assume he's dead while the White Man sinks to the bottom of the ocean and sinks into mud. He's not only still conscious, it's implied he's also constantly feeling the pain of having been freshly kicked in the nuts. He is eventually rescued... ''one million years later'', where an alien race picks him up on a long abandoned desolate Earth. By this point the White Man has long since gone gibbering insane and the aliens throw him in a zoo, assuming humans were an unintelligent species.
* ''ComicBook/DoctorStrange'' isn't above inflicting this on his enemies. An amateur sorcerer sends his remote projection to blackmail Strange into giving up his chokehold on mystical knowledge, and Strange initially acquiesces. When the sorcerer projects himself again to reap his reward, his astral form is trapped in a small jar from which he can't escape. Strange places him among rows of identical jars and walks away from the sorcerer's panicked screaming.

** In post-''Secret Wars'' Marvel, magic has a serious cost. For Strange this takes the form of [[BodyHorror giant tumorous growths that plague his body like a cancer.]] In order to alleviate the worst of it, he passes off his own suffering onto [[spoiler: an artificial being he keeps locked in his basement.]] Later, Strange is forced into a prolong and desperate fight with [[TheFundamentalist The Empirikul, dimension-hopping and genetically enhanced super scientists who want to destroy all magic]]. When Strange is finally victorious, the Empirikul's leader [[spoiler:wakes up blindfolded and chained in a basement as Strange reads the spell of subsitution.]]
* In a ''ComicBook/GhostRider'' annual written by Warren Ellis, the Scarecrow (not the Batman villain) creates a haunted house sown together with live human beings. Upon defeating him, [[spoiler:Ghost Rider breaks every bone in the Scarecrow's body, then twists every bone in the Scarecrow's body so the bones will not heal properly, thus leaving the Scarecrow as a permanently paralyzed and disjointed mess.]] He later got better.
* The Deacon is paralyzed in the last issue of ''ComicBook/{{Ghost Rider}}s: Heaven's On Fire''. Total paralysis. He'll never move again. And he's going to spend his days in prison with the All-New Orb. Surely, this is a fate worse than death. This was actually ''intended'' as the ultimate punishment - rather than killing him and having him join his master Zadkiel, having him suffer through a pathetic life.
* In ''ComicBook/ImmortalHulk'' #2, Bruce Banner gets attacked by a MadScientist who used his research to become immortal but ended up turning into a creature resembling a Ghoul from ''VideoGame/{{Fallout}}'' as a result. He used his son as a test subject but ended up accidentally killing him as a result, and buried him not knowing his corpse was radioactive and killing anyone who passed by it in the graveyard. To punish him the Hulk tears off his limbs and [[BuriedAlive leaves him buried him alive miles underground, unable to die]].

* In ''ComicBook/TheInfinityGauntlet'' mini-series, Thanos turns his granddaughter Nebula - who had been severely injured, but saved by one of Thanos' own henchmen, who got killed by his master for this kindness - into a floating near-corpse who is an intermediate state between life and death, not being allowed the luxury of death despite being twisted, broken and mutilated. [[spoiler:She got better.]]
* Magus from ''ComicBook/TheInfinityGauntlet'' and [[ComicBook/Warlock1967 Adam Warlock]] / ComicBook/{{Thanos}} fame / infamy ended as this. Due to reality altering energies being unleashed as he held the incomplete Gauntlet, he ended up as an intangible, invisible, inaudible apparation. He can see others but not interact with them. Scream, but never be heard. ...Until [[ComicBook/CaptainMarvelMarvelComics Genis]]-Vell with his [[SpiderSense cosmic senses]] comes along, and a TimeyWimeyBall gets involved.
* This is the sad fate of ''Franchise/IronMan'' villain Justin Hammer. After being harassed by Hammer messing with his hormones, Tony discovers and heads to a satellite where the villain, stricken with a terminal illness, is living out his last days. A series of missteps by Hammer's men causes him to fall into his pool and Tony uses a special cryo-capsule to freeze the water he's in before the two are sucked out into space. However, by the time S.H.I.E.L.D. could get up to pick up Hammer's men, Hammer himself had drifted off too far into space, his disease stabilized by the zero-gravity of space but never able to escape.
* In ''ComicBook/MutopiaX'', two of Kaufman's henchmen are walking inside a warehouse belonging to one of Kaufman's deposed drug gang rivals. One of the henchmen is talking about the deposed drug lord. The other henchman says, "What a terrible way to end your life." To which the other henchman replies "Who said anything about him being dead?" [[spoiler:He is being suspended on top of the warehouse by chains, and later gets horrific revenge on Kaufman in a method that is left to the reader's imagination]].

* In the alternate Marvel Universe ''ComicBook/{{Ruins}}'', the Gamma Bomb that turned Bruce Banner into [[ComicBook/TheIncredibleHulk the Hulk]] instead turned him into [[spoiler:a huge mass of gigantic tumors and horrific maiming all over the body, which Rick Jones claims is still being kept alive in a CIA facility]].

** After meeting Gert's time traveling parents in the distant past and revealing to them what happens to them and their daughter, Nico casts a spell on them that [[spoiler:renders them unable to speak about or act upon the knowledge they learned from the kids and then sends them back to the time they left from]]. She even highlights it with the quote:
--->"On the outside they will be their normal selves but on the inside they will never stop screaming."

* At one point in continuity, all MarvelUniverse Skrulls lose their shapeshifting ability... and are stuck in whatever form they have at that moment, even those squeezed inside ''really tiny cracks and crevices''... One sleeper agent was in the shape of a lamp when the weapon was activated.
* ''ComicBook/SpiderManReign'': The fate of the Kingpin, who is kept alive via an intravenous drip for ten years and paraded out once a year in front of the mayor who eats a steak in front of him.
* In ''ComicBook/UltimateMarvel'', this is eventually revealed to be [[spoiler:Thanos']] EvilPlan, on a galactic scale: [[spoiler:he wants to make death something only he is allowed to experience, leaving the rest of the universe in an AndIMustScream state.]]
* In ''The ComicBook/UncannyXMen'', Doctor Doom once turned ComicBook/{{Storm}} into an organic chrome statue. She could not move but could still think. This turned into a case of UnstoppableRage because she is severely claustrophobic, and being unable to move made her completely insane. And her mutant powers were still working, so the claustrophobia manifested as a deadly storm overhead. Which expanded until it was a hurricane covering roughly half the planet. (By that point, even after Storm was freed, it was too large for her to control.)
** Creator/JossWhedon concluded his run on ''Astonishing X-Men'' by [[spoiler:permanently fusing ComicBook/KittyPryde with a gigantic bullet made of alien metal, after she phased it through the Earth in a HeroicSacrifice. The first issue of ''S.W.O.R.D.'' reveals that, over a year later, she's still alive and conscious, and getting further and further from home at apparently superluminal speeds.]] Although eventually she did [[spoiler:get back to Earth thanks to the actions of Magneto.]] She still can't scream. [[spoiler: She Got Better.]]
* In ''ComicBook/WhatIf'' vol. 2 #13, [[ComicBook/ProfessorX Charles Xavier]] rather than Cain Marko finds the Crimson Gem of Cyttorak and becomes TheJuggernaut, corrupting him into a mutant-supremacist supervillain. The issue ends with him ThrownOutTheAirlock and helplessly floating through space. As the Juggernaut, [[{{Immortality}} Xavier's immortal, indestructible body]] [[TheNeedless doesn't need air, food or water]] so he can survive this situation indefinitely. The ending narration is an IronicEcho of the Juggernaught's catchphrase, implying that he will float through space forever, fully conscious but powerless to '''do''' anything.

* New character Greymalkin from ''Young ComicBook/XMen'' has this as his origin story. He was buried alive by his abusive father roughly 200 years ago. The trauma caused his [[{{Mutants}} mutant]] powers to appear, and it just so happens said powers are superstrength and invincibility in total darkness. The poor guy was buried alive, immobile, for 200 years until he was freed. Beast comments that it's amazing he kept his sanity.

* ''ComicBook/SpiderMan'': This happened to the Juggernaut at the end of ''The Amazing Spider-Man'' #230, when ComicBook/SpiderMan buried him in tons of concrete.

* The ''ComicBook/AlphaFlight'' villain Master of the World was a caveman dissected cell by cell by an alien LivingShip, and his mind trapped in the ship's computer for ''forty thousand years'', conscious the whole time, before he got control of the ship and had a new body grown.
* This happened to the Juggernaut at the end of ''Amazing Spider-Man #230'', when Franchise/SpiderMan buried him in tons of concrete.

* In ''ComicBook/WhatIf'' vol. 2 #13, [[ComicBook/ProfessorX Charles Xavier]] rather than Cain Marko finds the Crimson Gem of Cyttorak and becomes TheJuggernaut, corrupting him into a mutant-supremacist supervillain. The issue ends with him ThrownOutTheAirlock and helplessly floating through space. As the Juggernaut, [[{{Immortality}} Xavier's immortal, indestructible body]] [[TheNeedless doesn't need air, food or water]] so he can survive this situation indefinitely. The ending narration is an IronicEcho of the Juggernaught's CatchPhrase, implying that he will float through space forever, fully conscious but powerless to '''do''' anything.

* New character Greymalkin from ''Young ComicBook/XMen'' has this as his origin story. He was buried alive by his abusive father roughly 200 years ago. The trauma caused his [[{{Mutants}} mutant]] powers to appear, and it just so happens said powers are superstrength and invincibility except in total darkness. The poor guy was buried alive, immobile, for 200 years until he was freed. Beast comments that it's amazing he kept his sanity.

** In post-secret wars Marvel, magic has a serious cost. For Strange this takes the form of [[BodyHorror giant tumorous growths that plague his body like a cancer.]] In order to alleviate the worst of it, he passes off his own suffering onto [[spoiler: an artificial being he keeps locked in his basement.]] Later, Strange is forced into a prolong and desperate fight with [[TheFundamentalist The Empirikul, dimension-hopping and genetically enhanced super scientists who want to destroy all magic]]. When Strange is finally victorious, the Empirikul's leader [[spoiler:wakes up blindfolded and chained in a basement as Strange reads the spell of subsitution.]]

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!Franchise/MarvelUniverse

** Somewhat mitigated at the end of the season finale in Episode 9 when [[spoiler:Uatu charges him with keeping watch over the miniature pocket dimension containing the pitched battle for the Infinity Stones between Killmonger and the Vision body possessed by the A.I. consciousness of Arnim Zola after it killed Infinity Ultron.]] He's not alone in the technical sense but still doesn't have anything to really do other than that.

* In the ''WesternAnimation/FantasticFour'' 90's animated series, Doctor Doom uses his new cosmic powers which he stole from the Silver Surfer to inflict this on Ben Grimm by slowing his metabolism down to the point where he can't move or speak, but is still aware and becomes in Doom's words a "living statue" for the rest of his life. Fortunately, Crystal reverses it when she finds him.

* In ''ComicBook/ImmortalHulk'' #2, Bruce Banner gets attacked by a MadScientist who used his research to become immortal but ended up turning into a creature resembling a Ghoul from ''VideoGame/{{Fallout}}'' as a result. He used his son as a test subject but ended up accidentally killing him as a result, and buried him not knowing his corpse was radioactive and killing anyone who passed by it in the graveyard. To punish him the Hulk tears off his limbs and [[BuriedAlive buries him alive miles underground, unable to die]].

* In the alternate Marvel Universe ''ComicBook/{{Ruins}}'', the Gamma Bomb that turned Bruce Banner into [[ComicBook/IncredibleHulk the Hulk]] instead turned him into [[spoiler:a huge mass of gigantic tumors and horrific maiming all over the body, which Rick Jones claims is still being kept alive in a CIA facility]].

* Magus from ''ComicBook/TheInfinityGauntlet'' and [[ComicBook/{{Warlock}} Adam Warlock]] / ComicBook/{{Thanos}} fame / infamy ended as this. Due to reality altering energies being unleashed as he held the incomplete Gauntlet, he ended up as an intangible, invisible, inaudible apparation. He can see others but not interact with them. Scream, but never be heard. ...Until [[ComicBook/CaptainMarvelMarvelComics Genis]]-Vell with his [[SpiderSense cosmic senses]] comes along, and a TimeyWimeyBall gets involved.

* Magus from ''ComicBook/TheInfinityGauntlet'' and [[ComicBook/{{Warlock}} Adam Warlock]] / ComicBook/{{Thanos}} fame / infamy ended as this. Due to reality altering energies being unleashed as he held the incomplete Gauntlet, he ended up as an intangible, invisible, inaudible apparation. He can see others but not interact with them. Scream, but never be heard. ...Until [[ComicBook/CaptainMarVell Genis]]-Vell with his [[SpiderSense cosmic senses]] comes along, and a TimeyWimeyBall gets involved.

* Magus from ''ComicBook/TheInfinityGauntlet'' and ComicBook/AdamWarlock / ComicBook/{{Thanos}} fame / infamy ended as this. Due to reality altering energies being unleashed as he held the incomplete Gauntlet, he ended up as an intangible, invisible, inaudible apparation. He can see others but not interact with them. Scream, but never be heard. ...Until [[ComicBook/CaptainMarVell Genis]]-Vell with his [[SpiderSense cosmic senses]] comes along, and a TimeyWimeyBall gets involved.

* Episode 4 of ''WesternAnimation/WhatIf2021'' focuses on an alternate Doctor Strange who lost his girlfriend Christine Palmer instead of the use of his hands. All the same events of ''Film/DoctorStrange2016'' happen, but afterwards, he begins delving into time travel with the hope of saving Christine. Sadly, [[InSpiteOfANail every attempt results in her dying another way]] since her death, as the Ancient One explains, is an "Absolute Point"; a pivotal moment in the timeline that ''must'' happen and is impossible to alter, since doing so would cause a RealityBreakingParadox. Strange, however, refuses to listen to every warning he's given and spends centuries gaining enough power to change Christine's fate. And when he finally does, it triggers the paradox he was explicitly warned would happen, since with Christine alive, Strange no longer had any reason to pursue the mystic arts and become Sorcerer Supreme. The resulting TimeCrash erases his entire universe from existence, [[AllForNothing and Christine along with it]]. The ''only'' thing left is a tiny crystal bubble, inside of which is the now-immortal Strange, [[MyGodWhatHaveIDone who realized the consequences far too late]] and is all alone [[NiceJobBreakingItHero with the knowledge that it's all his fault]]. ''Forever.''

!!Franchise/MarvelUniverse

* In ''The ComicBook/UncannyXMen'', Doctor Doom once turned ComicBook/{{Storm}} into an organic chrome statue. She could not move but could still think. This turned into a case of UnstoppableRage because she is severely claustrophobic, and being unable to move made her completely insane. And her mutant powers were still working, so the claustrophobia manifested as a deadly storm overhead. Which expanded until it was a hurricane covering roughly half the planet. (By that point, even after Storm was freed, it was too large for her to control.)
** Creator/JossWhedon concluded his run on ''Astonishing X-Men'' by [[spoiler:permanently fusing ComicBook/KittyPryde with a gigantic bullet made of alien metal, after she phased it through the Earth in a HeroicSacrifice. The first issue of ''S.W.O.R.D.'' reveals that, over a year later, she's still alive and conscious, and getting further and further from home at apparently superluminal speeds.]] Although eventually she did [[spoiler:get back to Earth thanks to the actions of Magneto.]] She still can't scream. [[spoiler: She Got Better.]]
* In ''ComicBook/UltimateMarvel'', this is eventually revealed to be [[spoiler:Thanos']] EvilPlan, on a galactic scale: [[spoiler:he wants to make death something only he is allowed to experience, leaving the rest of the universe in an AndIMustScream state.]]
* At one point in continuity, all MarvelUniverse Skrulls lose their shapeshifting ability... and are stuck in whatever form they have at that moment, even those squeezed inside ''really tiny cracks and crevices''... One sleeper agent was in the shape of a lamp when the weapon was activated.
* New character Greymalkin from ''Young ComicBook/XMen'' has this as his origin story. He was buried alive by his abusive father roughly 200 years ago. The trauma caused his [[{{Mutants}} mutant]] powers to appear, and it just so happens said powers are superstrength and invincibility except in total darkness. The poor guy was buried alive, immobile, for 200 years until he was freed. Beast comments that it's amazing he kept his sanity.
* ''ComicBook/{{Runaways}}'':
** After meeting Gert's time traveling parents in the distant past and revealing to them what happens to them and their daughter, Nico casts a spell on them that [[spoiler:renders them unable to speak about or act upon the knowledge they learned from the kids and then sends them back to the time they left from]]. She even highlights it with the quote:
--->"On the outside they will be their normal selves but on the inside they will never stop screaming."
** Later, Molly is attacked by a super villain who is getting revenge for something her parents did to him. It apparently was some sort of attack with their psychic powers, which left him completely paralyzed (unable to even blink) and lasted until they died. In other words, he spent seventeen years in a hospital, unable to move, and at the complete mercy of the hospital staff.
* Magus from ''ComicBook/TheInfinityGauntlet'' and ComicBook/AdamWarlock / ComicBook/{{Thanos}} fame / infamy ended as this. Due to reality altering energies being unleashed as he held the incomplete Gauntlet, he ended up as an intangible, invisible, inaudible apparation. He can see others but not interact with them. Scream, but never be heard. ...Until [[ComicBook/CaptainMarVell Genis]]-Vell with his [[SpiderSense cosmic senses]] comes along, and a TimeyWimeyBall gets involved.
* This happened to the Juggernaut at the end of ''Amazing Spider-Man #230'', when Franchise/SpiderMan buried him in tons of concrete.

* In ''Mutopia X'', two of Kaufman's henchmen are walking inside a warehouse belonging to one of Kaufman's deposed drug gang rivals. One of the henchmen is talking about the deposed drug lord. The other henchman says, "What a terrible way to end your life." To which the other henchman replies "Who said anything about him being dead?" [[spoiler:He is being suspended on top of the warehouse by chains, and later gets horrific revenge on Kaufman in a method that is left to the reader's imagination]].
* In the alternate Marvel Universe ''Ruins'', the Gamma Bomb that turned Bruce Banner into [[ComicBook/IncredibleHulk the Hulk]] instead turned him into [[spoiler:a huge mass of gigantic tumors and horrific maiming all over the body, which Rick Jones claims is still being kept alive in a CIA facility]].

* In a ''ComicBook/GhostRider'' annual written by Warren Ellis, the Scarecrow (not the Batman villain) creates a haunted house sown together with live human beings. Upon defeating him, [[spoiler:Ghost Rider breaks every bone in the Scarecrow's body, then twists every bone in the Scarecrow's body so the bones will not heal properly, thus leaving the Scarecrow as a permanently paralyzed and disjointed mess.]] He later got better.

* ComicBook/NewMutants: How do you deal with a sadistic person that can control people with her voice? [[spoiler: Simple. Use dark magic to completely remove her mouth, reducing her to a broken, weeping mess.]] Do not mess with Doug Ramsey. Seriously.
* Happens to ComicBook/{{Daredevil}} archenemy [[spoiler:Bullseye. Let's see...a demonically possessed Daredevil kills the guy in the ''Shadowlands'' story arc. Lady Bullseye manages to resurrect him, but he's completely paralyzed, has lost all his senses except his eyesight, and needs to be placed in an iron lung. Bullseye comes up with a rather elaborate plot to torment Daredevil and ultimately kill him. He fails and in the process loses his sense of sight. One of the most vicious, psychotic, and frightening villains in the Marvel Universe is now, in the words of Daredevil, "a living brain in a flesh and bone coffin."]]

* ComicBook/DoctorStrange isn't above inflicting this on his enemies. An amateur sorcerer sends his remote projection to blackmail Strange into giving up his chokehold on mystical knowledge, and Strange initially acquiesces. When the sorcerer projects himself again to reap his reward, his astral form is trapped in a small jar from which he can't escape. Strange places him among rows of identical jars and walks away from the sorcerer's panicked screaming.
** A professional thief shoots Dr. Strange and ransacks his home. When Strange catches up with the thief, he punishes him by trapping his physical body inside his own mind.
** In post-secret wars Marvel, magic has a serious cost. For Strange this takes the form of [[BodyHorror giant tumorous growths that plague his body like a cancer.]] In order to alleviate the worst of it, he passes off his own suffering onto [[spoiler: an artificial being he keeps locked in his basement.]] Later, Strange is forced into a prolong and desperate fight with [[TheFundamentalist The Empirikul, dimension-hopping and genetically enhanced super scientists who want to destroy all magic]]. When Strange is finally victorious, the Empirikul's leader [[spoiler:wakes up blindfolded and chained in a basement as Strange reads the spell of subsitution.]]
* Played for laughs with throwaway Deadpool villain The White Man. The White Man has Mandarin tech that allows his cane to turn people into stone; a fate he is subjected to when Deadpool, Luke Cage, and Iron Fist fight him in the 70's. He is unfrozen in the present day (Deadpool loves to mock comic book time) where it's revealed he was conscious and fully aware of his surroundings the entire time. He attempts to freeze Cage and Iron Fist and dump them in the ocean, but Iron Fist's students kick him in the balls, freeze him in a pose holding his crotch, and accidentally knock him overboard. The heroes assume he's dead while the White Man sinks to the bottom of the ocean and sinks into mud. He's not only still conscious, it's implied he's also constantly feeling the pain of having been freshly kicked in the nuts. He is eventually rescued... ''one million years later'', where an alien race picks him up on a long abandoned desolate Earth. By this point the White Man has long since gone gibbering insane and the aliens throw him in a zoo, assuming humans were an unintelligent species.

* This is the sad fate of Franchise/IronMan villain Justin Hammer. After being harassed by Hammer messing with his hormones, Tony discovers and heads to a satellite where the villain, stricken with a terminal illness, is living out his last days. A series of missteps by Hammer's men causes him to fall into his pool and Tony uses a special cryo-capsule to freeze the water he's in before the two are sucked out into space. However, by the time S.H.I.E.L.D. could get up to pick up Hammer's men, Hammer himself had drifted off too far into space, his disease stabilized by the zero-gravity of space but never able to escape.