A lot of the mamas, daddies, Brody, and other characters die and come back to life sometimes. Here is a list of all the times this has happened.
- Janice dies when Brody tells her to act her age. She also dies from Alzheimer's and from listening to Skrillex. Even God zaps her a few times.
- In Michelle's first video, she has salt poured onto her by slugs, which melts her.
- Shirley is shot by Brody in the first Call of Duty joke.
- Cathy has her neck broken when Batman slaps her in the joke where she breaks her arm when she slaps someone.
- Brody and the National Geographic guy are killed by Jane in the joke where they film the National Geographic in her bathroom.
- Donald Trump and the Mexican Guy turn to gold and stone, respectively, when Helga looks at them in the Trump deporting himself video.
- Brittany died in the grocery store, and also from being shot into space by an alien when she attempt to buy from his store using Starbucks coffee pouches.
- Jenny froze to death.
- Gretchen was crushed when a transformer transformed with her inside and died looking at herself in the mirror.
- So did Helga in the latter case, but the Grim Reaper refused to take her.
- Avery kills herself by jumping off the bed and, in another episode, Margaret ate her (while she hanglided using a Dorito).
- A falling helicopter dropped and killed Rachel at one point.
- Claudia had a KFC bucket sign fall on her face.
- Jenny once set Margaret on fire.
- This video features a montage of the deaths of the mamas.