WMG / Death Battle One On One Match Suggestions N To S

aka: Death Battle One On One Suggestions N To S

Death Battle suggestions for one-on-one matches with a common link, sorted from N-S:

• Main Page
• Backstories
• Combatants Relationships
• Recurring Trends
• Song Titles
• Suggestions
  • One-on-one with a common theme
    • A-F
    • G-J
    • K-M
    • N-S
    • T-Z
  • Groups of combatants with a common theme
  • Battle Royales/Team Battles
  • Joke Suggestions/Bad Ideas for a DB
  • Returning Combatants
    • Seasons 1-5
    • Seasons 6-10
    • Seasons 11-15
  • Original Tracks

A few things to keep in mind:

• Remember that they should have at least some common factor. Even the Starscream vs. Rainbow Dash had one; both being popular high flyers in their toylines in Hasbro. Also, no fanon interpretations of characters.
• No creepypasta. They have too many unknowns to be qualified combatants, and Death Battle is known for showing their research.
• Characters who run on the Rule of Funny are generally frowned upon. With no established limits, any scientific limits would be random. However, this doesn't really apply if that is the entire point; if you have a "just for fun" type match up, put it in the Jokes Battles folder.
• No Memetic Badasses after Chuck Norris and Segata Sanshiro (that match-up's enough, thanks!). The fun of the meme is kind of ruined when the show reveals and proves that they're not nearly as badass as all the jokes and facts say. And besides, the aforementioned match ended in an apocalyptic draw. ^note  Just to clarify, characters with memetic status are allowed to be listed here, but they shouldn’t be listed because of memes. For example, Shaggy can be listed here, but his Ultra Instinct abilities and other non-canonical feats must be completely ignored.
• If you see several characters carrying the same consistent theme in this page, be sure to move them here.

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N-P

• N (Pokémon) vs...
  • Marik Ishtar (Royal commanders of monsters who first fight against the protagonist but later aid them)
  • Seto Kaiba (Anti-heroic, commanding rivals who fight alongside a team of monsters and are most associated with a powerful dragon [N with Reshiram/Zekrom, and Kaiba with Blue-Eyes White Dragon])
• N (Xenoblade Chronicles) vs...
  • Anakin Skywalker (Former heroes who were swayed to the side of villainy by Cold Ham villains in response to the loss of their love interests, and ended up fighting against their sons)
  • Andrias Leviathan (Expies of Darth Vader who were once nice men who were once close to a particular woman [Leif for Andrias, and Mio/M for N] similar to the relationships of the protagonists. However, after they lost everything, including the woman that they are close to, they were manipulated by an evil being that gave them immortality in order to carry out their plans. The woman they were close to would end up betraying them [Leif would steal the Calamity Box while M would kill herself so that Mio could live], and they successfully kill the deuteragonist [though they're revealed to be alive after all shortly after]. However, after hearing the deuteragonist explain why the woman betrayed them and that they still care about them, they ended up finally standing up to the powerful beings that once controlled them)
  • Asch (Fallen Heroes whose lives were stolen by their morally-superior clones, with them instead becoming war-trained Dragons of the Big Bads)
  • Odio/Oersted (Once-noble warriors that, after experiencing several tragedies, including the death of the women they loved, fell into villainy [Oersted taking the mantle of Demon King Odio and N allowing himself to be corrupted by Z], their first acts upon turning to villainy are slaughtering the people they once swore to protect, were defeated by the heroes at the end reminding them of who they were, and both their games released a week apart from each other)
  • Salem (Semi-immortal former humans turned into a Moebius and Grimm respectively, who consulted with a Demiurge Archetype that's Made of Evil in order to bring back their dead love interests)
• Nagoriyuki vs...
  • Jetstream Sam (Honorable technology based samurai like swordsmen who enjoy the thrills of battle, served as rivals to the main character [Sol Badguy and Raiden], were forced into working under the glasses-wearing main villain against their will [Happy Chaos and Senator Armstrong], to whom they tried to rebel against, until they were finally set free living in peace until their fateful duel with their rival)
  • Lady Maria (Both are sword fighters who dualwield that come from a race that resemble vampires [the Nightless and the Vileblood], they can imbue their swords with their own blood which increases their strength and range, they however suppress this power, they hold great guilt for their past actions as to why they decided to seal themselves away [Nagoriyuki for his time under Happy Chaos's control and Maria for her role in the Fishing Hamlet])
  • Rokurou Rangetsu (Samurais with a passion for seeking worthy opponents, went to become non-humans [Rokurou becoming a Yaksha demon and Nagoriyuki becoming a nightwalker vampire], their demonic natures have downsides that make them lose control at the worst times, show the most respect for those that can give them a good fight, both serve powerful masters [Velvet Crowe and Happy Chaos], both went to help in the salvation of the world to pay a debt)
• Nami vs...
  • Rutee Katrea (Two money hungry women who act not out of pure greed but to support their home, with them being orphaned at a young age not even remembering their birth parents [Nami was found alongside her sister Nojiko by their adopted mother Bell-mère, who brought them back to her hometown of Cocoyasi Village and Rutee was brought to the town of Cresta and left at the Dunamis Orphanage where she would grow up], due to their past, both Rutee and Nami have a soft spot when it comes to orphans and children. In battle, they act mainly as support, preferring to fight from a distance using their weapons [Rutee use the Swordian Atwight, a magic sword imbued with the personality and memories of Atwight Eks a hero who fought in a legendary war 1000 years prior which let's her casts water, ice and healing spells. Nami uses the Clima-tact, a custom made bo staff that that let's makes her capable of manipulating the weather in seconds, typically in the form of gusts of wind or thunderstorms])
  • Yuffie Kisaragi (Kind-hearted and noble thieves that were originally antagonistic towards a small group of heroes, but eventually joining with said group in order to go on many adventures. They also have several elemental abilities thanks to their weapons, Nani's Clima-Tact and Yuffie's Materia)
• Naofumi Iwatani vs...
  • Cao Ren (Heroes that wield shields were called upon to protect their kingdom and will play villainous roles as long as it takes to stop tose causing chaos)
  • Hajime Nagumo (Heroes that were summoned to another world alongside a group of heroes by a church and were given powers persived as weak [Naofumi using a shield and Nagumo possesing alchemy], were eager and naïve but after getting betrayed by trusted allies they became moodier and angrier, both met girls that were also betrayed by their people that'd become great allies and love interest, they travel saving small towns, and both found that the churches that summoned them were not good as first looked)
  • Maple (Protagonists from Japanese light novel series set in isekai worlds who mainly use a shield to fight and strive to fight for what is right, despite the odds being stacked against them)
  • Mash Kyrielight (Shield-wielding protagonists from Japanese fantasy series who were sent to another world to save it from destruction)
  • Zamazenta (Shield-wielding heroes from fantasy stories who are capable of using their shield for offensive purposes just as well as for defensive purposes and are part of a group [Naofumi with the other weapon-based heroes, Zamazenta being one of the twin protectors of Galar with Zacian])
• Narancia Ghirga vs...
  • Coco Adel (Flamboyant members of a group who have abilities that allow them to fire projectiles and scan areas for enemies)
  • Frye (Flamboyant members of a group who wear yellow and have projectile-firing abilities from their sentient summons [Narancia with Aerosmith, Frye with her eels])
• Narciso Anasui vs. Jareth the Goblin King (Agent Peacocks with Villainous Crushes on the main female leads)
• Nathan Algren vs. William Adams (Western samurai)
• Nathan Garrett vs. Zelgius (Villains with enchanted swords and the label of black knight)
• Neco-Arc vs. Temmie (Strange yet comedic creatures with cat-like traits who break the fourth wall)
• Necrozma vs. Toichiro Suzuki (Power-stealing antagonists who seek to throw their worlds into chaos)
• Negaduck vs. Lord Shen (Evil avian rivals)
• Negi Springfield vs. Akko Kagari (Anime mages inspired by Harry Potter)
• Nelliel Tu Odelschwanck vs. Midna (Both are parts of a non human race living in a realm bathed in darkness [Nel is a Hollow that became Arrancar, that lives in Hueco Mundo; Midna is a member of the Twili race, that lives in the Twilight Realm], are former high ranking members of their species who would rise again later [Nel being the former 3rd Espada eventually regaining her power to fight again; Midna was the princess of the Twili before Zant overthrew her, but she defeats him later on and regains her throne], are betrayed by someone who was jealous of their power and status [Nel was backstabbed by Nnoitra, Midna was overthrown and cursed by Zant who wanted her throne], said betrayal leaving them in younger or impish state bodies [The crack Nnoitra left in Nel's mask made her spiritual energy seep out turning her into a younger state, this made her lose her memories as well for a time; Zant placed a curse on Midna with Ganon's power that turned her into a small imp], both meet and follow a man who they first annoy but eventually befriend [Nel runs into Ichigo and friends on their quest to save Orihime, Midna came across Link when he survived the corruption of the Twilight Realm and put in prison], they eventually faced the ones that betrayed them and put them in their current state, both engage in a fight with an opponent that failed to defeat which puts them in great danger [Nel turned back into her child state during her fight with Nnoitra while Midna tried to fight Ganondorf's spirit form but this ended in her death but gets better latter], have 3 forms that they appear in [Nel is seen in her child form, true adult form, and her Resurrección in which she turns into a centuar with a lance/spear like weapon; Midna is seen in her impish form, the form she gains with the full fused shadow with which she attacks with a spear, and her true adult form]. In contrast their personalities are complote opposites with Nel being happy and kind towards most, while Midna carries herself in a more cocky and entitled manner before warming up)
• The Nemesis T-Type vs...
  • Agent Venom (Nightmare Fuel super-beings created through top-secret programs armed to the teeth with military-grade weaponry. They both have forms of shapeshifting, hyper-regeneration, and Combat Tentacles - or more like symbiote tendrils. They've also got even stronger and more monstrous forms they can change into. )
  • The Big Daddy (Large, scary monsters who don't speak much, were created through genetic tampering, and designed for a specific goal with opposite relations to a certain group [The Big Daddies being created to protect the Little Sisters while the Nemesis T-Type was created to hunt down and kill members of S.T.A.R.S.])
  • Pyramid Head (Humanoid, brutish monsters with large weapons from two of the most beloved horror video game series of all time, with Nemesis wielding ranged weapons and mutating throughout its appearances while Pyramid Head wields a melee weapon and stays largely the same)
• Neopolitan vs...
  • Black Noir (Villains who serve as the right-hand to another villain as part of a group, are known for not speaking, and masquerade as someone else in some fashion)
  • Himiko Toga (Cute and Psycho girls, one extremely talkative, the other a mute, both having the power to disguise themselves as others)
• Nephrite vs. Sniper Wolf (Canine-themed snipers)
• Neptune/Purple Heart vs...
  • Kamen Rider Ex-Aid (Clumsy and absentminded caretakers with two personalities whose love of retro gaming is exceptionally relevant, as their job is keeping the peace in a world filled with threats related to that very subject)
  • Tohka Yatogami (Super energetic goddesses designed by Tsunako that fight using special swords, have a love for desserts, and can travel between dimensions and alter reality, though they'd rather just have fun)
  • Yu Narukami (Sword-wielding JRPG protagonists who draw power from their connection of others, and lead a team of heroes with similar powers to them)
• Nero vs...
  • Allen Walker (Silver-haired demon hunters who wield a cursed arm of symbiotic tissue to slay their foes, eventually gaining the ability to augment their arm with an array of anti-demon weaponry. Both were born without parents and with a genetic abnormality that connected them to the world of demons, with both eventually venturing to join an Order based around the extermination of demonic forces)
  • Hellboy (Snarky, revolver-wielding heroes who possess both a Red Right Hand and a demonic heritage)
  • Kazuma Torisuna (Protagonists with powers associated with their right arms who have dealt with holy organizations [the Order of the Sword and HOLY])
  • Luke (Brash Capcom characters who were promoted to The Heroes of their franchises' first games after their introductory games)
  • Vincent Valentine (Anti-heroic, Badass Longcoat-clad revolver users who wield demonic power)
• Nero Claudius vs. Homura Kougetsu (Women who suffered abuse from their mothers and where left to die [Nero was poisoned by her mother, Homura's mother abandoned her for her personal greed], fight with flamming swords that they can summon at any time, and have issues commucating with people [Nero because she's so full of herself and Homura ain't the best at chatting])
• Nia vs. Tiara (The first companions the main characters meet and treat them as beneath them at the beginning before falling for them during the journey, have secrets link to their past [Nia being a Flesheater and Tiara having the blood of the Vile Good running through her veins], both fight alongside an animal companion [Dromarch and Cui], both fight with the element of water and have healing spells, have super forms [Nia's Blade Form and Tiara's Fairize transformations], and both have a rival in romance who utilize the element of fire)
• Nick Fury vs...
  • Big Boss (Legendary, elderly commanders with Eyepatch Of Powers who are the leaders of private military organizations)
  • Judge Dredd (Elderly operatives of not-so-nice government institutions who outwit and overpower enhanced individuals with guile, experience, and basic weaponry)
  • Sergeant Avery Johnson (A military sergeant later revealed to have been a test subject for a Super-Soldier program)
• Nico Robin vs. Medusa (Smart and tall women with a love for learning about the past, are The Stoic of their teams [usually working as the voice of reason], suffered discrimination in their childhood that made them live in isolation which caused people to hunt them down, fight by controlling the arena before striking [Robin attacks from a distance with and Medusa gets up close], have abilities that can incapacitate enemies [Robin by growing arms that grabs them, and Medusa being able to petrify whoever looks at her], and have angelic motifs to them [Robin by using the Wing attack while Medusa using Bellerophon, that lets her call upon a pegasus)
• Nier vs...
  • Wander (Warriors from depressing fantasy games who wander across ruined landscapes, fight against monsters of darkness, and unlock seals to aid a magical figure in hope of them helping them save those they care for, with Nier's aid [Weiss] being played straight while Wander's aid [Dormin] manipulated him into doing his bidding and is responsible for his demise)
  • Xion (Tragic protagonists from RPG series made by Square Enix who are associated with two friends of theirs, fight using swords and summoned weapons, and returned from a Cessation of Existence that erased even memories of them)
• Nightmare Moon vs. Vertigo (Moon-dwelling maniacs)
• NiGHTS vs...
  • Klonoa (Eponymous protagonists of dream-themed platformers)
  • Peter Pan (Flying, playful figures who take children to mysterious realms to fight off against evil forces)
• Nina Williams vs. Christie (Profesional assassins from rival 3D fighting games that temporarily join powerful organizations and fight with rushing fighting styles [Aikido for Nina and She Quan for Christie])
• Nine vs...
  • Hilda (Witches of big power with Dominatrix personalities coming from 2D fighting games that crossover in the past, specialize in stage control, and have metal musical track)
  • Irene Belserion (Powerful well-endowed red-haired magicians that are responsible for their world's magic, are mothers to girls that took completely different fighting styles, fell from grace after their Dark and Troubled Past, were considered dead only to return later as villains, have several reality-warping abilities among other big pool of spells [Nine has big preferences for fire], and were a substantial asset in powerful teams [the Six-Heroes for Nine and the Alvarez Empire for Irene])
  • Semiramis (Powerful Hot Witches that take different styles of combat [Nine despite can throw projectiles enjoys attacking her opponents directly, while Semiramis rather have then submitted her opponents in poison], are capable of summoning powerful beasts that can shot laser beams, are in love with samurai-esque fighters, and and both died after getting slashed in the chest by a red-dressed heroes having a final moment to look at someone they hold dearly)
• Nitocris vs...
  • Candance (Similar looking women inspire by Egyptian mythos, children of divinity that are usually extremely pleasant despiye their high positions, they excel on water base attacks [Nitocris can also create clones, summon various types of monsters and open portals], and have several attack buffers)
  • Ishuzu Ishtar (Characters with Egyptian motifs, with knowledge and appreciation for their own mythos, have unortodox powers [Nitocris can talk with spirits and Ishuzu can persive the future], and fight by setting traps and summoning monsters)
• Nitori Kawashiro vs...
  • Kokonoe A. Mercury (Brilliant inventors that created the equipment presented in the vast majority of their franchises, work in their own terms, use their inventions as weapons to go against near godly foes, don't really move much in battle, and pull weapons out of their really deep pockets. In contrast, while Nitori is an energetic girl that does her inventions out of profit, Kokonoe does it out of her own personal reasons)
  • Mei Hatsume (Passionate inventors that always come with crazy inventions that they try to expose to investors for profit)
  • Thomas Edison (Genius inventors of their respected worlds with aforomented animal motifs, with Nitori being a kappa while Thomas Edison is a lion)
• Nitros vs. Regulus (Blue-clad antagonists from Bomberman games for the Nintendo 64 who get upgraded later, are the only surviving bosses of their respective games, and end up on Bomberman's side)
• Noctis Lucis Caelum vs...
  • 2B (Stoic protagonists who wear black and are expert weapon masters)
  • Charlemagne (Male royals that travel the world with their True Companions and fight using several types of swords [letting them do a Storm of Blades they can summon with their Hyperspace Arsenals)
  • Chrom (Sword-wielding royalty who lead a group of four people on grand adventures)
• Noel Vermilion vs. Kiana Kaslana (Artificial made clone of young innocent girls [Saya and the real Kiana Kaslana] with a story that belonged to another being [Mu-12 and Sirin/Herrscher of the Void respectfully] and got adopted by surrogate parental figures [the Vermillions and Siegfried Kaslana], come from worlds surrounded by radioactive energy [Seithr and Honkai Energy] formed by a complex and cosmological space that connecta every known world in their respective multiverses that supposedly grant limitless power [the Boundary and the Imaginary Tree], are designed to kill the godlike forces that seek to destroy the world [Original Units and Will of Honkai], both enroll in a military academy [Control Organization and St. Freya High] who would befriending someone they'd have to fight later on [Tsubaki Yayoi for Noel and Raiden Mei for Kiana], were manipulated by handsome looking villains [Hazama and Otto Apocalypse] which awakened their suppresed evil persona that wants to destroy the world, said rampage is stopped by a sacrifice made from a protagonist in red [Ragna the Bloodedge for Noel and Himeko Murata for Kiana], gaining control of themselves, now gaining these as super forms, would later go on to fight apocalyptic beinga that exist or have powers from a higher plane of existence [the Black Beast and Otto Apocalypse], fight with gunkata fighting styles, and when transform they can create piercing weapons [swords for Noel/Mu-12 and lances for Kiana/Herrscher of the Void], and both are extremely horrible at cooking)
• Noelle vs. Sirius (White haired combat maids of gacha games, with kind and reserved personalities, have flower motifs in theit uniforms [Noelles armor accessories and Sirius's sword], are part of a knight organization [Noelle is part of the Knights of Favonius and Sirius is a Royal Navy], can summon their swords and create shield projections, are very insightful in their field, are in love with the protagonist, and were originally doubtful of their ability until an event determined them to continue upon their path. In contrast, Noelle is sweet and innocent while Sirius can be sultry and suggestive, Noelle wears a modest armored maid outfit while Sirius's is revealing and short, and Noelle's an exceptional maid who is struggling to become a knight while Sirius is a formidable guard but flounders when trying to be a maid)
• Nora Valkyrie vs...
  • Nana Kozuki (Genki Girls that fight using special types of hammers that can morph into cannons, are part of teams that exterminate monsters to free the world [joining this group following said monsters killed their parents], and have insanely huge appetites)
  • Nobara Kugisaki (Orange-haired girls who attended an academy to learn how to kill the evil creatures in their worlds [Jujutsu Sorcerers killing Curses and Huntsman/Huntresses killing Grimm], having similar personalities which is being sassy, confident, and can get pretty hotheaded, yet jokey and goofy, have some kind of heart symbolism to them [Nora and Nobara having hearts on their hammers and on Nora’s outfits], and are apart of a team of teenagers, their companions in those trios are the black-haired, Intelligent, strategist guy [Megumi and Ren, respectively] and a more happy, tough, and dorky type guy who’s like the leader of the team [Yuji and Jaune, respectively]. Both have similar fighting styles that involve shooting projects, using explosives [Nora has her grenade launcher, Nobara can hit her nails like firing a gun and can use them as crash bombs], and obviously using hammers for melee attacks)
• Norman Jayden vs. Francis York Morgan (FBI agents from video games)
• NOVA vs. Hunter (Platform game protagonists who fight with boomerangs)
• Nozomi Kaminashi vs. Mogana Kikaijima (Highschool girls who develop fighting styles revolving around swimming and strive to make money in any situation possible to no longer being in poverty)
• Nu -No. 13- vs. Mélusine/Albion (Similar looking white-haired girls that fight with mystical swords, can fly at high speeds, admire fighters that use BFS [Ragna and Lancelot], and are Apocalypse Maidens that'll bring to the world dragon-looking monster that could destroy the planet, with Nu attempting this at any chance, while Mélusine avoids it as much as possible)
• Nui Harime vs...
  • Baby Bonnie Hood (Young girls who look sweet and innocent, but are actually two of the most psychotic and dangerous characters of their respective series)
  • Jagi (Evil adoptive siblings that serve as personal rivals to the protagonists [Jagi for impersonating Kenshiro and manipulating Shin, Nui for killing Ryuko's father] who are scarred by the protagonist in some form [with Jagi having his faceplate and helm to cover the disfiguring wound Kenshiro gave him while Nui having her prosthetic arms following Ryoko cutting them off])
• Nyarlathotep vs. Walter Padick/Randall Flagg (Immortals whose actions have cemented them as the overall Big Bad of their respective franchises, have taken many names and faces over the course of history, commit terrible actions against humanity simply of the sake of it, and who are really just a minion to their franchise's Greater-Scope Villain)
• Nyx vs. Solaris (Destroyer Deities prophecized to end all life who are divided into several pieces following a science experiment, with one piece being sealed inside the Big Good)
• Obelix vs...
  • Jerome (The strongest characters in both worlds, who also originate from different time periods)
  • Senator Armstrong (Large men with Super-Strength from different time periods, one a hero whose strength comes from magic, the other a villain whose strength comes from science)
• Obsidian vs. Shiny RoboBowser (giant fusion forms featured in final battles. Obsidian is used against a final boss while Shiny RoboBowser is one)
• Ochaco Uraraka vs...
  • Kat (Female superheroes who control gravity)
  • Yaya Yah (Feminine Nice Girls with a pink Color Motif who have powers based around controlling gravity)
  • Mitsuri Kanroji (Kindhearted heroines with pink motifs & incredible agility, use equipment suited for mid-range combat (grappling wire bracers & Nichirin whip sword), undergo an awakening that makes them stronger (Zero Gravity becoming non-contact & the Demon Slayer Mark appearing respectively), and even incorporate love in their individual philosiphies, complete with them developing a crush for one of their peers (Izuku Midoriya & Obanai Iguro respectively)
  • Siebren de Kuiper (a.k.a. Sigma) (On the surface, it's Gravity Hero vs. Gravity Villain, which is good as a start, but going deeper, it shows a powerful dynamic between Ochaco's desire to save people mentally as well as physically and Sigma's unfortunate mental disposition after his accident leaving him easily manipulated by Talon to villainy (not unlike a few members of the Paranormal Liberation Front), meaning there could be more stakes than a standard 1-on-1 at play.
• Odalia Blight vs...
  • Derek Powers (Abusive Parents and Corrupt Corporate Executives who share the name "Blight" (Odalia's last name and Powers' supervillain name) and whose actions force their abused children to team up with the main characters [Amity Blight's crush on Luz convinces her to stand up to Odalia, Paxton Powers forms an alliance with Terry McGinnis to take down Derek and take over Wayne-Powers])
  • Shania's Mother (Abusive Mothers who only see their daughters as means to an end and force them to become people that there aren't, which would end up doing a number on their self-esteem)
• Odelia vs. Doll/Anemona Rijndael (Automatons created by alchemy who have specific purposes to fulfill and eventually learn to grow beyond their functions)
• Odio/Oersted vs. Kiara Sessyoin (People who had suffered much from humanity and became evil because of it, with Odio wishing to spread hatred while Kiara wishes to spread love to everyone)
• Officer Howard vs...
  • Lloyd Bannings (Young police officers from science fantasy settings that focus on powerful strikes and also try to uncover several mysteries within their very police stations)
  • Rex (Protagonists from modern Creator/Nintendo video games with a blue color scheme who fight alongside a construct)
  • Sieg Wahrheit (Hack-and-slash protagonists whose fighting styles rely on swords and summoned Legions, with said Legions including Sword, Arrow, and Arm Legions)
  • V (Protagonists of 2019 hack-and-slash games whose fighting styles revolve around summoned allies. Both can also absorb dying enemies)
• Ogre vs...
  • Kotal Khan (God-like, Mayincatec bruisers from fighting games, with the former being an anti-heroic, honorable ruler while the latter is a mindless villain)
  • Necalli (Brutish Mesoamerican warriors who lived on Earth for centuries and long to fight strong opponents from fighting games)
• Okita Souji vs...
  • Yuuki Konno (Genki Girl sword fighters with fighting style revolving around fast-paced attacks who despite posessing incurable deseases)
  • Ukyo Tachibana (Videogame samurai inspired by real-life individuals that specialize in single strikes that had several slashes and have severe deseases)
• Okuyasu Nijimura vs...
  • Amethyst (Kind but cocky and reckless protagonists who are members of a group under the command of a high schooler who is associated with gemstones and refuses to kill others, with the former using melee fist strikes while the latter uses a long-ranged weapon)
  • Denki Kaminari (Hot-Blooded yet kind Idiot Heroes from Shonen Jump manga/anime)
  • Kazuma Kuwabara (Hot-Blooded and idiotic, yet good-hearted Japanese Delinquents from manga/anime series published by Shonen Jump, where at first antagonistic towards the protagonist until becoming their trusted right-hand, and have abilities that let them erase objects)
• Olimar vs. Papa Smurf (Tiny humanoids who are leaders of a larger group of smaller creatures [Pikmin & Smurfs] who routinely fight off bigger animals [PNF-404's fauna & Gargamel])
• Omnidroid vs. Tighten (Antagonists of CGI films created by the villains [Syndrome built the Omnidroid while Megamind accidentally injected Hal Stewart with Metro Man's DNA, causing Hal to become Tighten] to be "stopped" by them only to go out of control)
• Omnimon vs. Prima (Large white-clad leaders of a group of thirteen divinely powered warriors formed to serve a mechanical creator god [the Royal Knights and the Thirteen Primes], are part of a species of transforming cybernetic [one is digital and the other is robotic], both wield a special reality warping sword [the Grey Sword and the Star Saber] as well as a special internal energy almost entirely unique to them [Omega Inforce and the Matrix of Leadership], would come into conflict with a dragon-ish man of a similar species from their planets ancient history [Dorumon/Alphamon and Predaking], are semi-rivals to a black clad outsider member of their team [Alphamon and Megatronus Prime])
• The Once-ler vs. Jacques Schnee (Corrupt Corporate Executives who have access to ecologically destructive technology and rule their corporations with an iron fist)
• Opal vs. Unico (Winged unicorns from Sanrio anime. Opal always has wings while Unico's are part of a Super Mode)
• The Operator vs. Satan (Old vs. new battle of the Big Bads of internet horror series, who are supernatural beings, are interpretations of preexisting characters, have some form of Nightmare Face, and don't usually directly involve themselves in the series' conflict, instead commanding minions to do their bidding, one of whom is a hooded figure)
• Orochimaru vs. Medusa Gorgon (Snake-themed villains from manga/anime who conducted experiments in several characters and have major connections to a protagonist)
• Oscar Pines vs Human Raiden: (Humble Farmboys that are young and weaker version of a Big good [Oscar is the new host of Ozpin, Raiden is the new timeline version of Lord Raiden])
• Osmosis Jones vs...
  • U-1146 (West vs. East battle of humanoid cells who seek to protect their host against hostile viruses)
  • U-1196 (West vs. East battle of humanoid cells fighting viruses inside an unhealthy human body)
• ORT vs...
  • The Icon of Sin (Indestructible, apocalyptic entities that have the power to destroy Earth by transforming it [ORT's Crystal Valley rewrites the world on a level not even seen in Reality Marbles, the Icon of Sin could build up enough power to generate a black hole that sucks the Earth into Hell])
  • N'Zoth (Overwhelmingly powerful entities that hail from far beyond the planets that serve as their respective settings, incapable of being destroyed by normal mortal life.)
• Overhaul vs...
  • Diavolo (Leaders of criminal organizations that lurk in the shadows, have a powerful ability in their respected universe [Overhaul's self-titled quirk for himself, King Crimson and Epitaph for Diavolo], and needed a powerful ability to defeat them [100% Deku combined with Eri's quirk for Overhaul, Gold Experience Requiem for Diavolo]; both are also voiced by Kellen Goff)
  • Trafalgar Law (Crime lords from Shonen Jump manga/anime who can disassemble and reassemble objects, with the former being a vicious, cruel figure who never redeemed himself while the latter eventually became a hero)
  • Albert Wesker (Cruel antagonists who lead evil organizations, can kill with just a touch, preform experiments on others, mutated throughout their appearances, and desire power, with the latter being loving towards his boss while the latter killed his boss to get ahead in his schemes)
• Ozpin vs. Rose Quartz (Big Goods who are actually Secret-Keepers that inadvertently kicked off their series' stories through their "deaths", as well as wielding handheld weapons)
• Ozymandias vs. Azir Omah (Benevolent emperors base on real ancient egyptians beings, can summon creatures, are pretty arrogant and hammy, and can buff allies defenses)
• Pain vs. Edelgard von Hresvelg (Stoic-minded, calm, yet wrathful prodigies that were involuntary experimental subjects that were forcibly given a powerful artifact that distinguishes them from the rest in some way and formed a group for the purpose of ending a cyclical cycle of corruption in their nation, with the goal of establishing a new order across said nation. They would then eventually be defeated by the rebellion they oppose and would ironically pass the torch to their enemy, entrusting their desire to achieve their visions of peace)
• Palkia vs. Omega Shenron (Two dragon-like lifeforms who were created as higher beings as part of a group, made to do certain jobs. However, they usually go after their "comrades", and were eventually put down via what is the opposite of their powers)
• Palossand vs. DesertMan.EXE (living sand creatures consisting of a head and two arm-like appendages)
• Palutena vs...
  • Rosalina (Goddesses from Nintendo video game series who rule over a realm in a non-earthly realm [Rosalina ruling over the Comet Observatory in space with Palutena ruling Skyworld] who protect a race of divine beings [the Lumas for Rosalina, the angels for Palutena])
  • Princess Celestia (Heroic goddesses who can control light and enjoy messing with their subjects, but still mean well)
  • Midna (Rulers from Nintendo games who live in realms reflecting their opposite abilities, with Palutena [who has heavenly abilities] living in a realm of light while Midna [who has abilities based on shadows] living in a realm of darkness)
• Pannacotta Fugo vs...
  • Akame (Assassins who wield powerful toxins that can easily kill their targets, started out as promising children before their downfall, and unlocked special abilities after accepting their faults)
  • Chat Noir (Blonde pretty boys with the power of untold destruction)
• Pantheon vs. Leonidas (Spear and shield-wielding warriors inspired by spartans who are well known for being Defiant to the End)
• Papyrus vs. Sir Daniel Fortesque (Friendly Skeletons who build themselves as mighty warriors but are actually comical losers, with Papyrus being a talkative ham who utterly fails at his task of capturing humans, while Daniel is The Unintelligible who eventually becomes the hero he dreamed of being)
• Parvati vs. Martel (Goddesses with love for humanity that possesed the bodies of young girls [Sakura Matou and Collete Brunel respectfully] in order to be among humans, they are not fighters, yet they can manifest elemental attacks [light and thunder specifically])
• Pasadena O'Possum vs. Sandy Cheeks (Texan Funny Animals who are Blood Knights and take immense pride in both their heritage and their combat capabilities)
• Patrick Star vs...
  • Richard Watterson (pink Funny Animal, Fat Idiot, lazy and unemployed Manchild from cartoons)
  • Ed (Generally friendly and unintelligent cartoon characters with impressive strength)
  • Motu (Unintelligent cartoon characters with impressive strength)
• Peacemaker vs. The Soldier (Ax-Crazy rogue American "soldiers" [Peacemaker being an independent vigilante while the Soldier is a Phony Veteran] who pack a lot of heat)
• Penny Polendina vs...
  • Alisa Bosconovitch (Androids designed to past as teenage girls with their own artificial inteligence to back it up, have Artificial Limbs that can be removed if necessary, formed friendships with most of the main cast and can pull bladed weapons [Penny with several blades and Alisa with chainsaws] from within them)
  • Mack Hartford (Young-kind heroes from a popular series, but not a well-liked series who turn out to be an android made by their father and became human later on and has ties with relics)
• Pennywise vs...
  • Betty (Politically incorrect humanoid abominations that take the form of seemingly non-threatening things to avoid suspicion [clowns for Pennywise, children for Betty] but make them terrifying anyway and specialize in using fear and illusions in combat. They are also eat people while devouring mostly children. [Pennywise because they almost always have simple fears that it can easily "become", Betty because most of the magical humans she found were kids.])
  • Fiddlesticks (Eldritch Abominations that take the form of what their victims fear the most)
• Percy Jackson vs. Zagreus (Protagonists that are the sons of Greek gods [Poseidon for Percy, Hades for Zagreus] and are capable of fighting legendary monsters from Greek myth)
• Peridot vs. Cosmo (Green, flying magic users who come from lands of magic, partner with humans to increase their life quality, and have the power of dream/wish fulfillment. Peridot and Cosmo also both have dog and human forms. Both also had their respective shows premiere in the 2000s and get cancelled in the second half of the 2010s before continuing to get new content in 2022)
• Perry/Agent P vs...
  • Kitty Katswell (top secret agent animals)
  • Monkey (Exotic pets of young Mad Scientists who fight crime when their owners aren't looking)
  • Skipper (Deceptively smart, animalistic secret agents)
• Pete vs. Bluto (Brutish rivals of animated protagonists who seek their lover's affection but is always defeated by their rivals)
• The Phantom vs. The Shadow (sneaky, mysterious, often gunslinging pulp proto-superheroes)
• Pharah vs...
  • Drogoz (Flying Firepower characters from Hero Shooters who use jetpacks and rocket launchers to rain down death from above)
  • The Soldier (Soldiers who utilize rockets to attack their foes from rivalling team-based shooters)
  • Wing Divers (Females that use jetpack like armors to fly and shot enemies from the skies)
• Phoenix Wright vs Takayuki Yagami (Bunny-Ears Lawyer who wins cases by the skin of his teeth against former lawyer turned hardboiled detective)
• Pickle the Caveman vs. Barghest/Tam Lin Gawain (Powerful figures who have a reputation for not only being some of the most fearsome warriors of their respective worlds, but also for devouring the strong)
• Pip vs. Uncle Sven (Hero Shooter support characters who fight using potions and alchemy)
• Pitaya Dragon Cookie vs. Sodom's Beast/Draco (Playable Draconic Humanoid Token Evil Teammate characters from gacha games. Both possess exclusive classifications [Pitaya Dragon Cookie is the only Dragon Cookie in Cookie Run: Kingdom while Draco is the only playable Beast])
• Plachta vs. Sophia/Sophie (Beings resembling young girls who have a mysterious past and take residence inside an object owned by the game's protagonist)
• Plague Knight vs...
  • Ziggs (Short but formidable foes who utilize explosives in many different ways using science)
  • Pop Fizz (Crazy short potion using foe who use their potions in different and creative ways)
• Pogo vs...
  • Cham Cham (Green haired cave children that never stop at nothing, with a great enjoyment out of adventure usually laughing, and fight alongside animal friends [Cham Cham has Paku-Paku her bird, and Pogo has Gori a gorilla])
  • Gon (Diminutive, mute, animal-hunting protagonists of prehistorically-themed stories with Toilet Humour, with Pogo having killed the last living dinosaur while Gon is the last living dinosaur)
• Porky Pig vs. Goofy (Third members of iconic Power Trios who are Jack of All Trades and have unpredictable powersets)
• Potemkin vs. Iron Tager (Large grapplers with mechanical gauntlets who serve as soldiers from ArcSys fighting games)
• Powdered Toast Man vs. Really Really Big Man (Parody superheroes)
• Power vs...
  • Esidisi (Combatants who can weaponize blood)
  • Eunie (Blonde Lad-ettes with protrusions coming from their heads)
  • Seras Victoria (Blonde monster girls that are part of organizations tasked with hunting monsters [the Devil Hunters and the Hellsing Organization] and are paired with the main protagonists of their respective series [Denji and Alucard])
  • Skarlet (Female combatants able to weaponize blood)
  • Skarbrand (Bloodthirsty demons who are lacking in the intelligence department)
• Gremlin Prescott vs. Penelope (Two genius characters who are introduced as benevolent allies in their first appearance [Epic Mickey and Sly 3: Honor Among Thieves], only for the next game [Epic Mickey 2: The Power of Two and Sly Cooper: Thieves in Time] to reintroduce them as bitter, angry antagonists under the control of the main villain (the Mad Doctor and Le Paradox). Also, both Power of Two and Thieves in Time ended on cliffhangers that will never be resolved for as long as humans are the dominant species on planet Earth.)
• Princess Celestia vs...
  • The Radiance (Sun goddesses who control light and have opposite alignments)
  • ZedΩ (Winged leaders with The Power of the Sun)
• Princess Luna vs...
  • Dark Matter (Entities who embody darkness)
  • Luna (Magic-using moon princesses named Luna from casts mostly consisting of female non-humans)
  • Pitch Black (Wielders of darkness who can enter peoples' dreams)
• Prophet vs...
• Psaro the Manslayer vs. Duke Pantarei (Mysterious white-haired JRPG antagonist that share a hatred for humanity, view manking as corrupt for the slaughter the mytical beings of their worlds [Elves and Entelexeia respectfully], have trusty allies that have the complete opposite views [Rose and Elucifer] yet get murdeted by humans only to get Psaro and Duke to initiaze a way to gain superpower forms to destroy humanity, they fight with the use enhance magical swords, destructive spells, and several superforms, and they would go to redeem themselves after being defeated by the heroes [Psaro joined the Chosen Heroes party and Duke aid Brave Vesperia in their plan to destroy the Adephagos])
• Pudge vs. Roadhog (Fat Bastards who use a hook on a chain as a weapon)
• The Punisher vs...
  • Judge Dredd (Judge, Jury, and Executioner)
  • Peacemaker (Marvel vs. DC fight of violent, gun-wielding vigilantes, with the former being a tragic figure representing the failures of America while the latter is a mentally-unstable criminal who fights for American-branded "peace")
  • Soldier: 76 (Former military heroes turned violent vigilantes after life-changing tragedy)
• Puss in Boots vs.
  • Jean-Pierre Polnareff (Rapier wielders who are needlessly reckless and have cheated death)
  • Meowth^note THAT'S RIGHT (Theatrical, feline outlaws from worlds full of fantastic creatures, and who form a third of a trio of True Companions. Both are also huge ladies men.)
• Pyra vs...
  • Kida (Barrier Maidens whose power sources are being hunted by expedition teams and end up becoming the Love Interests of their stories' protagonists)
  • Nero Claudius (Female swordfighters dressed in red who are bound to the soul of their master, with their masters also fighting in wars and seeking things that are magical [Rex seeking Elysium while Hakuno seeks the Holy Grail)
  • Tahu (Mystical fire-themed beings from sci-fi franchises awakened by a seemingly normal character [Rex awakened Pyra, Takua called the Tahu to the Island]. They also have a light-themed counterpart connected in some way [Mythra is the other half of Pyra, Takanuva is the seventh Toa], and both get an upgrade that allows them to tap into all their worlds' elements [Pyra can transform into Pneuma for a short duration, Tahu's mask, the Hau Nuva, got upgraded to access all Kraata powers]. They also possess defense-themed artifacts [Pyra is the "Aegis", Tahu's mask is the "Mask of Protection"])
• The Pyro vs...
  • Black Noir (Masked villains who act as the right-hand to another villain as part of a group, are known for not speaking, and see the world through a different, cuter lense)
  • Firefly (Flamethrower-wielding pyromaniacs)
  • Leatherface (Murderous, masked madman who work alongside a group of fellow killers, wield two-handed weapons as their main source of attack [Leatherface with his chainsaw, the Pyro with his flamethrower], and are Silent Antagonists)
  • Mei (Fire vs. ice matchup of characters with similar roles from rival team-based shooters, with the former being a crazed maniac who has the mind of a child while the latter is a caring, brilliant scientist)
  • Roadhog (Masked criminals that take no issue with causing carnage, with the former using mainly ranged weapons while the latter uses melee attacks)
• Pyrrha Nikos vs...
  • Lady Sif (Formidable swordswomen who're among the greatest warriors in their respective realms)
  • Noriaki Kakyoin (Red-headed members of a team that they are considered the brains of, which both having lonely pasts and were eventually killed by major antagonists)
  • Tigress (Female Hyper-Competent Sidekicks to male Idiot Heroes who get a fair amount of Ship Teasing with them)

Q-R

• Qrow Branwen vs...
  • Eizen (Gloomy yet witty mentors who are associated with The Grim Reaper and are cursed in some fashion)
  • Shota Aizawa (Badass teachers, that both look like homeless people)
  • Spirit Albarn (presumably wielded by either Stein or Lord Death) (Familial figures to teenage female scythe-wielding protagonists, who also use scythes [or in Spirits' case, is the scythe])
• Quan Chi vs...
  • Jedah Dohma (Big Bads attempting to summon a God of Evil)
  • Taskmaster (Villainous characters who can copy the fighting styles of others)
• Queen Elizabeth vs. Charlotta Fenia (Little looking blonde girls from gacha videogames inspire by old british settings that are queens and constantly try for others to take them seriously despite their capabilities; and in contrast they fight in different styles with Elizabeth shooting with cannons and Charlotta using a magical sword)
• Queen Tyr'ahnee vs. Queen Vexus (Evil "queens")
• Quote vs...
  • Kaeru (8-bit run-and-gun protagonists designed by Studio Pixel)
  • Trace Eschenbrenner (Indie run-and-gun protagonists of Metroidvanias with a war in the backstory)
• Rachel Alucard vs...
  • Alice (Powerful, unholy entities with the appearance of young girls in fancy clothes who are associated with two demonic familiars [Nago and Gii for Rachel, Nebiros and Belial for Alice])
  • Remilia Scarlet (Powerful heirs of royal houses that follow the Vampire Lolita Archetype [Remilia even being the one who popularized it in Japan], are not as young as they look, are capable of summoning spears, are easily capable of fighting but they rather let their servants do it, and constantly challenge their fate [Rachel being a former Observer that interfered with time's course to help Ragna, while Remilia possibly has the power to manipulate fate]. Furthermore, while Rachel is normally as calm and collected as possible, Remilia is more of a Chuunibyou pretending to be cool and collected before letting the childish side out)
• Ragyo Kiryuin vs...
  • Medusa Gorgon (Villainesses infamous for being abusive mothers)
  • Lusamine (Big Bad mothers who are Ax-Crazy, borderline obsessed with alien lifeforms from another dimension [the Life Fibres and the Ultra Beasts respectively], wear variants of said lifeforms to become even more powerful, and are opposed by both the main protagonists and their own daughters)
  • Queen Zeal (Abusive mothers who are obsessed with beauty and plan on having humanity be enslaved to the Life Fibers and Lavos respectively)
• Rain vs...
  • Weather Report (Children of powerful families who were separated from them at birth with arrogant demeanors [by default with Rain, as Wes Bluemarine with Weather Report], seek to avenge loved ones who were killed at the hands of major antagonists of their series [Shao Khan and Argus for the former, Enrico Pucci for the latter], have the ability to control water and electricity, are named after musicians [Prince for the former, Weather Report for the latter])
  • Zabuza Momochi (Villainous ninjas who fight using blades and hydrokinetic abilities and have esteemed titles they are disconnected from [Rain being a member of the royal family of Edenia that was rejected due to his status as a bastard child, while Zabuza is feared as the "Demon of the Hidden Mist" for ending the practice of the Seven Swordsmen of the Mist])
• Rainbow Mika vs. Ángel (Sensual female wrestlers from fighting games whose stories involve corrupt organizations who host tournaments)
• Raistlin Majere vs. Elric of Melniboné (Sickly albino sorcerers)
• Ramenman vs. Min-Min (Chinese fighters from Japanese works that have a ramen motif and implement unorthodox fighting styles in their respective tournaments [Ramenman using kung-fu on a wrestling tournament and Min-Min using kicks on a tournament focused on arms])
• Ramlethal Valentine vs. Altera (Two artificial creations of powerful beings [The Universal Will and the Umbral Star/Sephar], were created to destroy humanity and appear as the main antagonist but are actually pawns for them,were thought to be emotionless, with even themselves thinking that, but with the help of another character [Sin Kyske and Hakuno Kishinami], they grew emotions and rebel against their creators, fight with super powered swords that shot lazer beams, and were also based from another being [Justice/Aria and Sephar])
• Ramuh vs. Ivan the Terrible (Gigantic and immortals all powerful lords of lightning of opposing moralities that are capable been summoned by heroes)
• Randy Cunningham vs...
  • Jayden Shiba (teenage high-school heroes clad in red and black suits based on Japanese warriors [Ninja and Samurai respectively] who inherited their suits from another and protect their hometowns from the forces of evil)
  • Rinko Kougyoku (teenaged high school protagonists associated with the color red and fight to save those corrupted by dark magic from the Big Bad)
• Ranma Saotome vs. Matsuri Kazamaki (Teenage boys trained in fighting arts who become girls after being cursed)
• Raoh vs...
  • Garou (Former pupils of great masters who became powerful, anti-villainous martial artists who serve as the antithesis to their protagonists, seek to band their worlds together under a common cause [Raoh to unite the people of the world under his command to restore order, Garou to unite the world's heroes to fight against him] and to become even more powerful than they already are, have an honorable side, betrayed their masters, and can copy others' techniques)
  • Nosferatu Zodd (Blood Knight antagonists who act as the rival to the protagonist, and live to battle strong opponents, but are also incredibly honorable)
  • Radahn (Large, imposing, armored commanders who are part of a significant group, are often seen with their horses [with Raoh having the massive, muscular Kokuoh while Radahn has the diminutive and scrawny Leonard], and are associated with stars)
  • Younger Toguro (Muscular, powerful rivals to heroes from classic manga/anime who seek to fight strong opponents and are honorable despite their status as villains)
• Raphtalia vs. Suzuka Gozen (Brunette beastly swordswomen who wield katanas, both their worlds follow J-RPG-esque rules, have extreme loyalty to their masters and will do anything to protect them nor take kindly those who disrespect them, refer to themselves as their master's swords, have a rivalry with a fellow servant [Filo and Tamamo-no-Mae], can perform magic arts, can use said magic to buff their atacks, and have abilities that lets bypass special defenses [Hengen Muso and Divinity])
• Ra's al Ghul vs...
  • Baron Zemo (Marvel vs. DC fight of terrorists and assassins who lead organizations dedicated to these causes who stand in opposition to major protagonists)
  • The Mandarin (DC vs. Marvel battle between Fu Manchu inspired villains with magical powers that lead dangerous organizations of assassins)
  • Will Anthonio Zeppeli (Mentors to the protagonist who dedicate their lives studying a technique used to obtain eternal life, with the former being a villain who embraces the technique while the latter is a hero who fights against it)
• Rashid vs. Shun'ei (Capcom vs SNK fight of the "new generation" heroes who have a fondness for technology, use elemental powers, and have an old mentor)
• Raven Beak vs...
  • The Didact (Alien warlords who seek to conquer other planets, wear armor, and mutate themselves to increase their strength)
  • Thragg (Warlords who lead a group of a species related to the protagonist of each work)
• Rayquaza vs. Bahamut (Draconic deities among the most powerful among their group of monsters who lend their power only to those who are worthy of it, utilize a wide variety of elemental abilities, and are often associated with meteors [Rayquaza is often tasked with destroying one in various games it's in and Bahamut was inside a meteor that it emerged from])
• Reaper vs...
  • Androxus (Dark and edgy masked gunslingers who are obsessed with death and excel in close-quarters combat)
  • Noob Saibot (Edgy, vengeful assassins dressed in black outfits and masks who have shadow-based magical abilities)
• Red Skull vs...
  • Black Mask (supervillains with a Skull for a Head)
  • Cobra Commander (Commanders of Nazi-eqse terrorist groups who fight against heroes that are the pure image of American patriotism)
  • Ra's al Ghul (Supervillainous leaders of powerful organizations, with the former pursuing technology and a modern hegemonic view while the latter weaponized traditional assassination methods and magic to aid others in their goals)
  • Rudol von Stroheim (Superpowered Nazis from comics)
• Red Sonja vs. Xena (Female barbarians with Dark And Troubled Pasts who receive powers from the gods [Sonja from the Celtic Scathach to satisfy her desire for revenge, Xena's from the Greek Ares out of implied parenthood])
• Ren Kogyoku vs. Juvia Lockser (Heroines from Shonen franchises that specialized on water attacks and manipulation, were enemies of the heroes at first, befriended a blonde member of the team, and fell in love with a strong dark hair man)
• Reimu Hakurei vs. Arle Nadja (Cute yet powerful female mages who are kind to others and fight against dark entities)
• Reinhardt vs...
  • Fernando (Knights in futuristic Powered Armor who use large, rectangular energy shields)
  • Jayce (Heroic adventurers with eccentric personalities who wield enhanced hammers that can fire off energy blasts)
  • Nora Valkyrie (Hammer-wielding powerhouses with eccentric personalities that may or may not just be fronts to hide their past trauma)
  • Vaseraga (Large knights with equally large weapons who used to command a unit of soldiers until they lost command over them in the same battle that they received a crippling injury [Reinhardt losing an eye while Vaseraga was paralyzed from poison], to which they were recruited by an organization that gave them the augments required to allow them to keep fighting, with Reinhardt honoring the sacrifice his mentor made [having died in the battle that took Reinhardt's eye] while Vaseraga is haunted by his failure to protect his crew)
• Rentaro Satomi vs. Naoto Kurogane (Similar-looking teenagers that lost their right arm and left leg before getting them replaced with prosthetics that enhance their strength who fight alongside twin-tailed girls against supernatural monsters)
• Reshiram vs. Blue-Eyes White Dragon (Legendary white dragon Olympus Mons who can fuse together with other, similar dragons to become even more powerful)
• Revolver Ocelot vs...
  • The Spy (Double Reverse Quadruple Agents of their respective series that are European [with the the Spy being French while Ocelot is Russian-American] and are influenced by the Spy Fiction genre)
  • Xigbar (Gunslingers who lose a part of their body to a swordsman during a battle, and act as The Dragon to the Big Bad while in truth actually being the true mastermind behind everything)
• Revy vs...
  • Kuroko Koumori (Ax-Crazy, female protagonists from manga who fight other villains with firearms and martial arts, with the former being a criminal herself while the latter is a serial killer turned criminal investigator)
  • Rebecca (Violent female mercenaries residing in Vice City settings who specialize in Guns Akimbo)
• Rex vs...
  • Bartz Klauser (Brown-haired, sword-wielding protagonists from RPGs who became legendary heroes [despite their original status as orphans] by defeating an originally ordinary entity who became corrupted y dark influence into becoming a god-like figure)
  • Nanashi (Once ordinary looters from RPGs who joined forces with a spiritual entity after originally dying to an evil, hegemonic figure [Jin for Rex, Adremelech for Nanashi], summon other spiritual entities to attack, and have green markings to show their bond)
  • Shu Ouma (Protagonists who found a girl that let them have the power of wielding a magical BFS [Pyra and Inori respectfully] with the ability to use other types of weapons from other individuals [Blades for Rex, schoolmates for Shu])
  • Sorey (Protagonists from fantasy RPGs whose liking towards ruins caused them to bond with a mysterious girl and fight alongside elemental constructs)
• Richard Nixon vs. Mecha-Hitler (Controversial political figures who were given Historical Villain Upgrades and robot bodies)
• Rick Grimes vs. Joel Miller (anti-heroic, undead-battling Papa Wolves from post-apocalyptic settings)
• Rico Rodriguez vs. Nathan "Radd" Spencer (grappling hook combatants)
• Richard Kimble vs. Number Six (men of TV shows perpetually in conflict with and trying to escape relentless authorities)
• Ridley vs...
  • Andross (Villains from sci-fi Nintendo video games who killed the protagonist's parent/parents, seek to conquer the universe, and have returned from the dead multiple times to fight the protagonist once more)
  • Death (Major recurring bosses of the two Trope Namers of the Metroidvania genre. Both become final bosses in rare cases, and both killed fighters in trailers leading up to the release of Super Smash Bros. Ultimate)
  • Mumkhar/Metal Face (Ruthless, despicable invaders of the main protagonist's hometown/colony that are responsible for the death of loved ones close to the main protagonist, constantly taunt them over it, and become cyborgs to avoid death)
  • Vile (Recurring antagonists in video game series starting arm cannon-wielding heroes that serve the main antagonist as their right-hand instead of being final bosses, themselves being violent, sadistic criminals with a purple color scheme)
  • Vilgax (Vicious alien warlords who have no issue harming children or their loved ones)
• Right Hand Man (Reborn) vs. Dr. Fetus (Top hat wearing Cyborg villains from indie games)
• Rika vs. Rena Lanford (Both are supporting heroines of sci-fi JRPG games whose humanoid alien origins are easy to identified by pointy ears [Rika is a Numan and Rena is a Nedian], they grew up leading peaceful yet isolated lives, they'd go on to fall in love with the main characters in the course of their journeys, the two are the living culminations of the hope of their species [Rika was the product of a thousand years of genetic years while Rena's mother sent her 700 million years into the future to save her life from a destructive experiment gone wrong], the girls specialize claws and knucklea for physical combat and are the most proficient healers in the team. In a dark contrast: Rika would become the basis for future generations of the Numans to come, while Rena becomes alongside two others the last of her species following the destruction of her planet)
• Rikochet vs. El Tigre (Mexican child heroes)
• Rin Okumura vs...
  • Allen Walker (Main protagonists from manga/anime who are exorcists)
  • Shinra Kusakabe (Fire manipulators with a demon motif who both been targeted as the ones that'll bring the apocalypse)
  • Moka Akashiya (Supernatural highschool teens who had their powers sealed to conform with humans, and are constantly removing those seals to battle strong threats, including several members of their own family.)
• Rio Kamashiro/Rio Kastle vs. Sailor Mercury (Ami Mizuno) (Bright blue haired girls who are seen as great geniuses in their schools, make use of ice powers [Mercury focuses on both water and ice, and Rio summons monsters associated with ice], are reincarnations of their previous aliens life forms; and in contrast Rio is loud and proudful while Ami is quite and shy)
• Risotto Nero vs. Skarlet (Assassins who specialize in weaponizing their targets' blood)
• Rivet vs. Tawna Bandicoot (Modern PlayStation game heroines who are the female counterparts of an animalistic hero from another dimension who fight against alternate counterparts of evil doctors)
• Rixia Mao vs. Kiku Shinobu (Young women from eastern inspired backgrounds, faced struggles due to their families traditions [Rixia trained to inherit her father's title of legendary assassin Yin and Shinobu was meant to become a shrine maiden], found new passions when traveled to foreign lands; both fight with fastpace swordplay, make use of elemental attacks [with Shinobu focusing on electricty], and use concealed weapons)
• Rizlet of Loggervia vs. Estelle Sidos Heurassein (Warrior Princesses that joined a guild of adventurers and fight with a Magic Knight style)
• R.O.B. (AVGN) vs. The Supreme Leader (Antagonists of popular video game review channels who aim to change all of a specific type of game [bad games for the former, sports games for the latter] into one specific game/games [Gyromite and Stack-Up for the former, Dick Vitale's "It's Awesome Baby" College Hoops for the latter])
• Robbie Rotten vs...
  • Dick Dastardly (Two recurring comical purple-clad villains of shows owned by Warner Bros.)
  • Mayor Humdinger (Two recurring comical purple-clad villains of popular kids' shows that have aired on Nickelodeon. Both of them also have blue-clad heroes opposing them)
• Robbie Reyes vs...
  • Kamen Rider Ghost (Teens with dreams of a good life in the future involving a family member, until one day they are suddenly killed at random but come back with due to an outside force reviving them giving them super spiritual powers, and in this new form they are equipped with a blade, black jacket, and go by a title with the word "ghost" in it, and are now on a mission to stop anybody who preys on the weak)
  • Rick Taylor (Once normal humans who were revived by a manipulative supernatural entity to seek vengeance in hopes of them succumbing to their dark side, with Robbie fighting against Eli's wishes for Robbie to become a cold-blooded killer while Rick gave into the Terror Mask's demands for violence)
• Roberta vs. Toko Fukawa (Bodyguards of sons of powerful families who went through events that spawned alter egos that are nigh-unstoppable killing machines with infamous monikers [The Bloodhound of Florencia & Genocide Jack respectively], that, in spite of their respective reputations, both have also managed to suppress those sides)
• Robin vs...
  • Matoi (White-haired heroes with amnesia that happen to be the workaholic in their teams, can be seeing as among the most powerful magicians, are their games Deuteragonists, and are Apocalypse Maidens that can bring back an ancient evil [Grima for Robin and the Profound Darkness for Matoi])
  • Soma Cruz (White-haired scholars who are associated with fighting using swords and grimories, are meant to serve as the vessels of ancient creatures of darkness attempting to lead to world to infinite darkness [Grima and Dracula respectfully], and go on to canonically reject their fate, although both have alternative timelines in which they succumb to their inner darkness)
• Robin Hood vs...
  • King Arthur (Classical heroes of legend)
  • William Tell (Mythological archers known for their ludicrous arrow-shooting skills)
  • Zorro (Legendary folklore heroes who are classified as wanted criminals whose journies start with their vendetta against what the rich did to them and their town and are masters of their skills In bladed weapons as well as being skilled horsemen)
• Robo-Ky vs. Springtron (Robot versions of white and blue main characters from fighting games)
• Rock Howard vs...
  • Cassie Cage (Children of major fighting game protagonists [albeit an adopted one, in Rock's case] who become the face of a "next-generation" cast)
  • Lars Alexanderson (Bastard children of powerful antagonists from long-running fighting game franchises, focus on powerful strikes combine with eletricity, and wear mostly red costumes)
  • Luke Sullivan (Blonde-haired proteges of major fighting game protagonists who become the face of a "next-generation" cast)
  • Trish Una (Heroic children of gang leaders who are adopted by heroes and fight using mêlée attacks)
• Rohan Kishibe vs...
  • Maxwell (Users of immensely powerful, writing-centric reality-warping abilities)
  • Yusuke Kitagawa (Stoic and mature yet eccentric artists who fight with the aid of Fighting Spirits)
• Roland Deschain vs...
  • Train Heartnet (Masterful Gunslingers with a dark past and a preference for revolvers)
  • Jonah Hex (The most famous gunslinger in literature VS the most famous gunslinger in comics. Both are war veterans who have dealt with the supernatural, survived in post-apocalyptic worlds and, occasionally, gone through time travel)
• Rorschach vs. V (Masked, morally-dubious vigilantes who fight against corruption from comics created by Alan Moore that received movie adaptions in the 2000s)
• Rose Quartz vs. Summer Rose (Rose-themed dead mothers of protagonists with unique power that passed down to the their childrens)
• Roxas vs. Axl (Inhuman humanoids who were once integral parts of antagonistic organizations before leaving due to the organization's actions, despite their comrades' attempts to stop them)
• Rouge vs. Ladybird (female thieves with flight and superhuman strength)
• Roy vs...
  • Elsword (Teenage, red-haired swordsmen with pyrokinesis)
  • Jayden Shiba (Both are swordsmen who are associated with the element of fire that are members of well-respected groups of warriors passed down from generation to generation [The Shiba Clan and Pherae, respectively] with their own fathers being their predecessors and were suddenly thrust into becoming leaders but managed to step up and lead groups to protect their hometowns. Both are also very noble, honorable, and stoic warriors who are willing to risk their lives to help others)
  • Kyle Dunamis (Young heroes voiced Jun Fukuyama who are sons of warriors that save the world in the past and do their best to uphold their parent's legacy)
• Roy Mustang vs. Percival Wales (Rude heroes that rule respective parts of their kingdoms that also strike to have bigger positions [Roy trying to become Führer of Amestris, while Percival is an heir to a noble house from a country neighbouring Feendrache], fight with pyrokinesis over their types of power, and have an Odd Friendship with blonde heroes)
• Ruby vs...
  • Bunnicula (extremely powerful red-eyed rabbits loyal to female masters)
  • Cosmo (Dimwitted magic users who come from lands of magic to Earth and partner with pink-clad humans to increase said humans' life quality. Both Ruby and Cosmo also have wands and both rabbit and human forms)
  • Cream (Superpowered rabbits made by Sega)
  • Reisen Udongein Inaba (Extremely powerful red-eyed rabbits with eye-based powers)
• Ruby Rose vs...
  • Alpha (Main protagonists of Web Animations with superhuman abilities and a red motif)
  • Baby Bonnie Hood (Little Red Fighting Hoods)
  • Dead Master (Scythe users who wear black clothing)
  • Death Jr. (Scythe users who wear black and shoot guns)
  • Maka Albarn (Heroic, scythe-wielding Action Girls who attend a school run by an immortal headmaster that trains people to hunt evil creatures, lead a team of fellow students, are raised by a single father, have powers connected to the soul, and fight an evil woman who infiltrated their school, as well a Humanoid Abomination who the evil woman serves, who has a familial connection to the immortal headmaster)
  • Margaret Moonlight (Gun-scythe wielding Action Girls)
  • Marluxia (flower-motif scythe wielders)
• Ruckus vs. Toby (Little guys in Mini Mechas who love destruction)
• Rudeus Greyrat vs. Arthur Leywin (Extremely talented mage protagonists of Isekai literature with very similar backstories — both reincarnate into a fantasy world to a gentle mother and a swordfighter father, first demonstrate their magical prowess by destroying part of their house, get separated from their family when they are young due to a tragic accident before eventually reuniting with them, become more experienced with the help of various mentors and adventurers before eventually attending a Wizarding School [Ranoa Magic Academy and Xyrus Academy] and getting into contact with enigmatic higher beings [The Human God and the Asuras], and have a Childhood Friend Rescue Romance with a silver-haired elf [Sylphy and Tessia])
• Rufus vs. Bob (Big fat guys who a capable of moving crazy fast despite the massive size and hate the idea of becoming slim)
• Rukia Kuchiki vs...
  • Shana (Short swordswomen that serve as their series female lead, are supernatural in nature [Shinigami and Flame Haze], are part of military organizations [Gotei 14 and Flame Hazes] dedicated into stopping dangerous and monstrous beings [Hollows and the Guze no Tomogara], both have similar reserved personalities with very temperamental times, are tasked with the responsability in preserving balance between the human world and otherwordly supernatural world, they would come to ally themselves the main heroes [Ichigo Kurosaki and Yuji Sakai] who were ordinary Japanese high schoolers turned empowered by said supernatural ways at the start of the story, they can use spells that require fundamental mystical energy, fight using katanas with contain spirits [Sode no Shirayuki and Nietono no Shana], is always ice vs fire)
  • Yami Ichika (Sisters to a high ranking member of an organization [Rukia's brother Byakuya being one of the Gotei 13 and Ichika's brother Yami being a royal knight of the Clover Kingdom], are skilled swordswomen and use a type of energy to boost their powers [Rukia using Reishi and Ichika using both magic and ki], are members of organizations meant to keep peace [Rukia being a Shinigami and Ichika being one of the Ryuzen Seven], their power up forms contrast [Rukia'a Bankai giving her a white outfit and hair while Ichika's Dark Cloak gives her a pure black aesthetic])
• Ryougi Shiki vs. Alexandra Trese (Short, black-haired women whose families have been connected to the forces of the supernatural spirits and demons since times of old, fight in the night-lit streets of Asian metropolitan areas [Tokyo and Manila] against all manner of ghosts and supernatural beings [and even against people with same paranormal abilities], fight using knives, can use special magical abilities [Shiki uses her Mystic Eyes of Death Perception, while Alexandra has acces to several spells, magical enchantments and summoning magic], seem cold and distant to everyone but have a soft spot for their closest allies and friends, have a dead "twin" that they still have a connection to [Shiki's other personality SHIKI was lost after an accident which prompted Shiki to act more boyish, as if trying to connect with him, and Alexandra's twin Sinag died and became her spirit-forged knife], and are revealed to be connected to powerful Gods that rule over creation itself [Shiki being revealed to be connected to the Swirl of the Root itself, manifesting as a deitu simply called "Void Shiki", while Alexandra is prophesied judhe of the God of War and Rebirth Datu Talagbusao, and in an alternate future Alexandra actually becomes the judge of the universe, destroying it and recreating the world]
• Ryuji Sakamoto vs. Sailor Jupiter (Electromancers who fight monsters with a fighting squad and gain new forms in their journeys. Both are often mistaken for delinquents due to their appearances and are generally the muscle of the group)
• Ryohei Sasagawa vs. Akihiko Sanada (Similar looking highschool boxers that are part of organizations that fight against evil and have control over an element [Ryohei with fire and Akihiko with lightning], and both got stronger as they grew older. In contrast while Ryohei is quite dumb, Akihiko is pretty smart)
• Ryuji Yamazaki vs...
  • Kano (East vs. west fight of brutish psychos for hire who were enhanced in some fashion [with Kano being enhanced through technology while Yamazaki was enhanced through dark magic], love to fight dirty, and have an rivalry with a major protagonist and their love intrest [Johnny Cage and Sonya for Kano, Terry and Blue Mary for Yamazaki])
  • Kaoru Hanayama (Brutal, fist-fighter yakuza who possess extreme amounts of strength and durability, with the former being an honorable, compassionate protagonist who never cheats while the latter is a ruthless, friend-less fiend who gladly uses dirty tricks)

S

• Sabo vs. Alibaba Saluja (Blonde-haired, pyrokinetics who despite their royal status became revolutionaries)
• Sachiko Shinozaki vs....
  • Cassidy (Ghostly children from murder mystery horror games killed by a shadowly purple man and come back as vengeful ghosts that haunt the building they died in and also murder anyone else who enter both out of rage and being unable to tell the killer from random people)
  • Gabriel (Ghostly children from murder mystery horror games killed by a shadowly purple man and come back as vengeful ghosts that haunt the building they died in and also murder anyone else who enter both out of rage and being unable to tell the killer from random people)
• Saeko Busujima vs. Aya (Ms. Fanservice sword fighters that fight against hordes of the undead)
• Saga vs Itachi Uchiha (Both powerful characters from iconic Shonem Jump franchises that main fighting style revolves around illusions. Have brothers to which they put in situation close to death (Saga leaving Kanon to drown, and Itachi using Tsukiyomi on Sasuke), but both died, later to be brought back from the dead by the enemy forces (Saga was revived to be a slave to Hades, and Itachi by Kabuto's Edo Tensei), but instead they gave then the slip (Saga never been in Hades side and just waiting for an opportunity, while Itachi used a Genjutsu meant for Sasuke in order of releasing himself). They're brothers also used must of their techniques and equipment, while also joined their teams/organizations for a short bit, Sasuke as an "honorific" Akatsuki member that used all of Itachi's jutsus, while Canon used Saga's Gold Cloth)
• Sagat vs...
• Sage Harpuia vs...
  • Tenzin (Wind-using leaders of air-based groups)
  • Twinbats Ryno (Fast green-clad flyers who dual wield melee weapons, attack with wind and lightning, and are allied with both a fire and a water user)
  • Zaheer (Air-elemental leaders of antagonist factions with members of all four elements)
• Sailor Moon vs...
  • Pegasus Seiya (Strong powerhouses from retro anime that are embodiments of the cosmos, team leaders, along with love interests who they protect)
  • Reimu Hakurei (Powerful female mages who exist in universes where most powerful entities (be they their allies or foes) are female, to which both fight against powerful entities to protect mankind)
  • Sakura Kinomoto (The two most famous magical girls in manga/anime history, who have had a rivalry since the 90s)
• Saint George vs. Sigurd (Legendary warriors whose most well-known feats were slaying a mighty dragon)
• Sakata Kintoki vs. Laxus Dreyar (Buff, manly fighters with contrasting personalities [Kintoki's a Ideal Hero while Laxus is an arrogant Jerk with a Heart of Gold] that make use of lightning attacks, have big Calling Your Attacks tendencies, can buff their electric powers, and are Semi-Divine [as Kintoki's father is the God of Thunder and Laxus is a lightning Dragon Slayer])
• Sakura Amamiya vs. Juna Crawford (Passionate young women that are fangirls of previous main characters in their franchises [Sakura Shinguji and Lloyd Bannings], modeled their fighting styles after them, joined said idolms organizations [The Imperial Combat Revue and the Cross Police Department], defended their homelands out of the absence of their old heroes, and they can fight with proper weapons [a katana and tonfas] and mechas [the Koubus and the Drakken II respectfully])
• Sakura Kasugano vs...
  • Akane Tendo (Japanese schoolgirl martial artists)
  • Asuka Kazama (Kind-hearted, female martial artists from Japan who have two rivals, one being the main protagonist of each work [Ryu for Sakura, Jin for Asuka]] and the other being a noblewoman in a dress [Karin for Sakura, Lili for Asuka])
  • Shingo Yabuki (Two fighting games excitable fanatics which fighting styles are imitations of out the main characters [Ryu and Kyo Kusanagi]. In contrast, Sakura shows great talent for the Ansatsuken and gets supported by Ryu whenever they spar, while Shingo doesn't have a proper base and Kyo shows little care in teaching him)
  • Videl Satan (Energetic, female proteges who aspire to become expert martial artists)
• Sakura Kinomoto vs...
  • Nanoha Takamachi (A battle between iconic anime Magical Girls)
  • Illyasviel von Einzbern (Prisma Illya) (Young magical girls who wear pink dresses and fight using cards that grant them several powers from different spirits)
• Sakura Matou vs. Nadeko Sengoku (Childhood friends of the main character that have romantic feelings for them, have pretty positive personalities that mask their issues, had their bodies forcibly modified by worms and snakes, and eventually achieved red-eyed, white-haired Superpowered Evil Sides that makes them gods that attempt to kill their previous love interest)
• Sakuya Izayoi vs...
  • Formidable (Knives vs Guns, maids with time stopping powers)
  • Lieselotte Sherlock (Time manipulators loyal to a demonic titled being [Remilia Scarlet and Arata Kasuga]. Both solve incidents that pose threats to their world and fight supernatural beings based on myths and religion. They are closely associated with vampires and mansions though from opposite spectrums [Sakuya works under a vampiric master who took her in her care in the Scarlet Devil Mansion, Liese as a child had her home mansion invaded by vampires which led to her awakening her powers], After these events they would don a new name)
• Sa'Luk vs. Vega (Human fighters who wear claws on their knuckles)
• Sanae Kochiya vs. Nepgear (Young girls relatives to goddesses [Sanae is the distant descendant of Suwako Moriya and Nepgear is Neptune's sister], are more physically develop that their elder relatives, gain power in accordance to people's belief, have fourth wall awareness, wear charms on the left side of their heads, thier duties consist of slaying monsters, protect their homeworld, and spreading their relative's patronage, they're pretty intelligent in the scientific and engineering [Sanae is knowledgeable in nuclear science and Nepgear is a mechanic], but can be airheaded sometimes with other topics, have trouble making decisions for themselves, geek out for mechas, befriend people they should be enemies with [Reimu Hakurei and the other CPU candidates], have control over multiple elements, have the power to summon gods and wield their powers in combat. In contrast, Sanae is always eager for a fight while Nepgear's usually is against it, Sanae's powers are based on religion and magic while Nepgear's on sci-fi and technology, and Sanae was extremely overconfident in her heritage before arriving in Gensokyo while Nepgear often underestimates herself and her powers)
• Sandman vs...
  • Clayface (Supervillains made of sand and clay respectively that can physically alter their bodies, and eventually underwent a Heel–Face Turn)
  • Crocodile (Villains with the power to control and turn into sand and have a weakness to water)
• Sanger Zonvolt vs. Star Saber (Two of the most badass swordmasters in the Super Robot Genre renowned for their strong sense of justice which is sometimes marked by moral ambiguity [Sanger is sometimes a Heel–Face Revolving Door depending on the game, while Star Saber was infamously portrayed as a psychopathic Knight Templar in the IDW comics]; this fight could also involve their respective combining partners [Elzam von Branstein and Victory Leo])
• Sans vs...
  • Ness (Partially a meme-based fight, but with honest connections of the two being from mascots of beloved RPG series [to which the latter's inspired the former] who are pacifists with magical abilities to allow them to fight against an all-powerful evil entity, with the latter being a loner while the former fights with their friends)
  • Shedinja (Undead One-Hit-Point Wonder monsters from RPGs that are surprisingly hard to kill)
  • The Judge (Recurring side characters from popular indie RPGs who are Perpetual Smilers, guide a protagonist who is an avatar [Frisk for Sans, the Batter for the Judge] have brothers who die [or at least can die, in Sans' case], and fight the protagonist when they try to destroy everything)
• Sasha Kreutzev vs. Lambda-11 (Blonde and silent women with the powers to control several swords from a distance, works for organizations that fight against supernatural entities [Annihilatus and Sector 7], have been mind controlled in the past [the Archangel Gabriel and Kokonoe])
• Sasha Waybright vs. Leonidas (Once corrupt tyrants related to the protagonist [Sasha being one of Anne's best friends while Leonidas is Euden's brother] who used force to get others to do their bidding and ruled their respective kingdoms with an iron fist, but after having an epic battle with the protagonist [two in Sasha's case], they went into hiding, only to emerge as competent leaders who become essential allies to the protagonist)
• Sasori vs. Relius Clover (Marionette Masters who are Evil Puppeteers)
• Satou Matsuzaka vs. Nagito Komaeda (Mentally unstable teenagers that lost their parents at a young age, put a dark twist on a positive concept that they became obsessed with as a result of their trauma [love for Satou, hope for Nagito], have only one person that can be truly considered their friend before they end up turning on them [Shoko for Satou, Hajime for Nagito], and end up starting a fire as part of a failed attempt to mislead others regarding their death.)
• Satsuki Kiryuin vs...
  • Stocking Anarchy (Master Swordswomen who wield katanas, wear white transformation outfits, have long, dark hair, are the sister of their respective series' protagonist, betrayed their "allies", and were made [at least in part] by the same people)
  • Kuvira (Female dictators with super powers)
  • Edelgard von Hresvelg (Female members of a royal family that were experimented on at an early age, join a prestigious academy that they later wage war against, lead small groups, seem tyrannical but in truth want humanity to live free of the influence of a powerful, female being, and have rivals who re their siblings, with Satsuki having a blue and white color scheme and believing in power while Edelgard has a red and black color scheme and believes in justice)
  • Henry Cooldown (Wicked Cultured, sword-wielding rivals to red-and-black-colored, anti-heroic siblings who act as both protagonists and antagonists)
• Savage Opress vs. Mariko (The second most powerful being in an alien race who are only surpassed by their siblings and wield invisible weapons)
• Savanti vs...
  • Enerjak (Omnipotent villains who are arrogant and vindictive with the ability to warp space and time and were originally good until they were introduced to magical powers and became evil. Both have also fought against a time traveler and despite all the powers they have would lose against them)
  • Kang (Supervillains that specialize in Time Travel)
• Saxton Hale VS...
  • Kano (Muscular Awesome Aussies who run an organization that engages in less-than legal activities, and who fight anyone who gets in their way)
  • Senator Armstrong (Muscular Blood Knights with Super-Strength and baritones)
  • Shizuo Heiwajima (Badasses with Charles Atlas Superpower. The former is a Blood Knight while the latter is a Reluctant Warrior unless provoked)
• Scar vs. Kurapika (Scarlet-eyed agents of vengeance as they called themselves and are the best among their people until they were slaughtered by another faction)
• Scarlet Spider (Kaine Parker) vs...
  • Shana (Anti-Heroic Tsunderes associated with the color red, who develop over time into more conventionally heroic characters)
  • K' (Edgy, anti-heroic successors to main protagonists that became protagonists after having their genes manipulated)
• Scáthach vs. Zhongli (Powerful and wise masters of spear-wielding fighting styles that they use in very unortodox ways, have been masters to several warriors, are in constant praise for their appaereance, tend to explain lost of details to people, have friendly enemies [with Medb and Tartaglia respectfully], have buffing abilities, are immortal beings that cannot die as are basically walking gods [with Scáthach being the Warrior-queen of the Land of Shadows and Zhongli is the God of Contracts], hold extreme grief for several mistakes they made in life, constantly strive to protect their allies [Scáthach by jumping first into battle as she won't die, and Zhongli by buffing everyone], and quickly became among the most popular characters in their franchises)
• Sadao Maou vs...
  • Jahy (Demon lords that were forced upon to Earth, losing most of their powers, now living in a small apartment, and working in food establishments)
  • Tohru (Entities of chaos and destruction from other worlds who have been reduced to more mundane service jobs [Maou at a fast food joint, Tohru being a maid] while still retaining most of their power [albeit it took a bit for Maou to regain some of his power], and becoming somewhat attached to human characters [Chiho Sasaki and Kobayashi].)
• Sazer Mithras vs. Kitana (female Combat Hand Fan users)
• Scott Pilgrim vs...
  • Travis Touchdown (Nerd turned vigilante)
  • Viewtiful Joe (Idiot Heroes driven by the love for their girlfriends. Scott can weaponize video games while Joe can weaponize filming techniques)
• Scourge the Hedgehog vs...
  • Emperor Joker (Practically Joker characters from comic books who absorbed the powers of the Master Emerald and Mr. Myxyzptlk respectively to become all-powerful adversaries capable of defying all dimensional laws)
  • Xeno Turles (They're lookalike evil versions of the main characters who utilize existencial items to power up, they lead of a group of people they use as pawns, they would get transformations that are darker paralales to that of their counterparts, were saved mad doctors [Fu and Finitevus], and both constantly wish to rule)
• Sealas vs. U-Olga Marie (Both are former members of organizations that attempt to stop time alterations [Time Patrols and Chaldea], and would later return as enemies that enforce justice, and also have the powers to create portals that let's them travel through timelines. They contrast on how they become who they are, Sealas was seen as the perfect example of what a Patroller should be and everyone look up to him unlike Marie that was deem an useless lider and incampable of being a Master, Sealas would betray the Time Patrollers out of his own volition while Marie was the one getting betrayed, they would later be sealed, and Sealas is fully aware of what his doing while Marie is mind-controlled after getting experimented on.)
• Sekiro/The Wolf vs...
  • Jin Sakai (Ninja vs. samurai battle of protagonists of 8th generation action-stealth games taking place in historical Japan. Both fight with a combination of swordsmanship skills and pragmatism, start their story by being defeated in a Hopeless Boss Fight, are left for dead, get rescued, and are initially driven by the goal of saving someone close to them)
  • William Adams (Sword-wielding protagonists from Japan-inspired Souls Like RPGs who start their games in pursuit of someone and are revived after dying during their adventure, with the former being a ninja while the latter is a samurai)
• Selvaria Bles vs...
  • Excella Noa Aura (White-haired women with big social positions [Selvaria is Brigadier General of the Empire's Central Forces and Excella in the princess of Lombardia] that fight with gigantic spears, wear black clothing, are Anti Villains despite being on enemy forces, are master tacticians that are persived as the biggest enemies for the main characters, they despise the spread of bloodshed but do so out of loyalty to their lieges [Selvaria's loyalty to Prince Maximilian and Excella to her father], can overcome hundred of enemies on their own, and have presence in crossover fighting games)
  • Ishtar (Sympathetic top enforcers of ruthless imperial princes [Maximilian and Julius], that don't fully agree with their superior's views and actions, yet still remain undyingly loyal to them out of love for them, yet in truth both these relationships are extremely toxic in nature [Selvaria is regularly subjected to emotional manipulation by Maximilian and Julius's love for Ishtar is more mutual however the man is literally possessed by his story Satan's equivalent], are descendants of ancient bloodlines [Valkyrur and the Crusader Thrud] which allowed to use special unique weapons [the Valkyria's Lance/Shield and the Mjolnir tome], and in the end their devotion to their abusive lords would inevitably lead to their downfalls, yet in their final moments gave a moment to spare on their enemies)
• Sen vs. Tamamo Cat (Cat-themed girls from gacha games that use large clawed hands to fight and deny that they're actually cats at all.)
• Senator Armstrong vs...
  • Dian (Big Bads who fight to purge the weak so the strong can survive, have played ball-related sports [football and basketball], own giant, fire-belching rides weaker than themselves, are fist-fighters with superhuman strength, are durable to the point only specific weapons [Jetstream Sam's sword and combined Jewelpet magic fired out of Rinko's Jewel Stick, and Dian has also lost to a unique sword] can do any lasting damage to them, can light their fists on fire and perform fire attacks, and were defeated by a hero with white hair and glowing red eyes [Raiden and Ruby])
  • Funny Valentine (well-intentioned, superpowered patriots who seek to guide the United States to a new age of prosperity)
  • G (Idealistic, influential politicians who embody their beliefs and have secret agendas that, when completed, would supposedly help the people of their world, with Armstrong seeking to strengthen their country through war while G seeks for world peace)
• Sergeant Keroro vs...
  • Neco-Arc (4th-wall-breaking joke characters who act as mascots for their respective series)
  • Zim (Comically incompetent alien invaders)
• Sesshomaru vs. Byakuya Kuchiki (extremely powerful Aloof Big Brothers and Bishounen)
• Seto Kaiba vs...
  • Blue/Gary Oak (Arrogant, anti-heroic rivals who command monsters to attack and are most associated with a reptilian right-hand [Blue/Gary with Blastoise, Kaiba with Blue-Eyes White Dragon])
  • Kamen Rider Gemn (Insufferable Geniuses who are heads of a video game company)
• Sessyoin Kiara vs. Belial (Dark Messiahs that embrace humanity's depravity, want to see what humanity will become if they continue down their dark path, are masochists, are some of the strongest characters in their verses [even capable of destroying worlds], have attacks named after religious concepts, are capable of summoning demons, and are so powerful in their Ultimate Forms [Beast III/R for Kiara and Avatar for Belial] that they could only be defeated in special circumstances)
• Shantae vs...
  • Beast Boy (Heroes who transform into animals to fight against evil)
  • Kat (Cute superpowered teenagers who are the local heroes of their hometowns)
  • Midna (Female video game characters who attack using their hair)
  • Sash Lilac (Purple-haired half-breeds who can attack using their hair)
  • Shego (Female experts of magic and combat with a Hero vs. Villain dynamic)
  • Twintelle (Creator/{[Nintendo}}-created Action Girls who fight with their hair)
  • Wren (Local heroines with animal abilities)
• Shard vs. χ-kai- (Dark and black copies of blue protagonist [Sonic and X] created by a mad scientist [Eggman and Wily] to kill the protagonists, but were separated by their creators for their "errors", they still share similarities despite wanting to be their own person [Shard being carefree and optimistic like Sonic while Kai shows fairness and hatred for the use of dirty tricks], they both originate from an alternate take from the main canon. In contrast, Shard has nothing against Sonic and managed to be his own without killing him and will go to sacrifice himself to protect Sonic and Tails, later to get rebuild, while χ-kai- was found by Serge and sworn to kill X so that everyone can see him as his own person)
• Sheeva vs. Looma Red Wind (Female, high-ranking commanders of a war-hungry race of four-armed monsters)
• SheZow vs...
  • Ranma Saotome (Teen boys who have the superpower of transforming into a woman)
  • Tail Red (East vs. West battle of teen boys with the power to become female superheroes)
• Shinmen Takezo vs. Miyamoto Usagi (fictional versions of the same legendary swordsman)
• Shinya Kogami vs. John Anderton (East vs. West. Animation vs. Live-Action. Members of organizations that attend to stop crimes before they can occur, but eventually got targeted by those very organizations [Shinya becoming an Enforcers, essentialy executioners and John getting persecuted for a crime he hasn't commited])
• Shirou Emiya vs...
  • Johnny Joestar (Left mentally scarred young men struck on massive tragedy, developed nonexistent senses of self-worth, have massive survivors guilt and endless almost disturbing determination to achieve their goals, after meeting a wise mentor they're taught a supernatural art developing a unique ability that they can use to reinforce and weaponize objects by grasping a specific shape as well as the spiritual context that connects to it's physical composition, they entered into a battle royale-like event relating to the possession of a treasure connected to tradition western theology, only to soon become embroiled in the deep conspiracy that surround it eventually facing a narcisistic blonde ruler [Gilgamesh and Funny Valentine])
  • Hyde Kido (Two normal highschool students that one night chance their lives forever [Shirou's witnessing Archer and Lancer's fight and Hyde's meeting Linne only to be attacked by a Void gaining an Insulator later on], they would get the ability to summon swords, both used to practice kendo but picked again so they can polish their fighting skills, they have interacted with nearly any of the main female cast in their series, and are great cooks who usually make dish for everyone around)
  • Kiana Kaslana (Teenage heroes who suffer amnesia regarding the early years of their life who inherited the will to save everyone from their father figures who begin the story with cripplingly low self-esteem but slowly begin to treat their life with more value over the course of the story who gain the capacity to wield swords in an unorthodox way (Kiana is the only character with non-APHO battlesuits that can use aerial attacks, Shirou can launch swords with Unlimited Blade Works) and an ability to replicate the techniques of others (Kiana uses Bronya and Fu Hua's abilities in the Everlasting Flames short, and Shirou can project weapons that he's seen) after beating an opposing version of themselves (Sirin and Archer) who conclude their stories separated from their loved ones (At least in the Fate route and the Good Ending of Heaven's Feel for Shirou)
  • Shichika Yasuri (Unorthodox swordsman [Shirou creates swords and Shichika uses his body as a sword], were trained by their deceased fathers, they both fight alongside girls that will die near the end, defeated several opponents in order to get an ancient relic [The Holy Grail and the Deviant Swords])
  • Touma Kamijou (Young selfless protagonist that usually face any enemy at front without any doubt, have a prodigy tsundere after them [Rin Tohsaka and Misaka Mikoto], have befriended rulers of Britain [Artoria Pendragon and Queen Elizard], are considered the lowest within their worlds power system, yet have great counters for most supernatural powers [Projection Magic and Imagine Breaker], and their personalities weren't properly portrayed in their stories anime adaptations)
• SHODAN vs...
  • AM (Digital Abominations who are genocidally vengeful against the human race)
  • BB (Female AI that serve as antagonists in their respective series and have absolute dominion over cyberscapes [the Moon Cell for BB, the Citadel Station for SHODAN])
  • XANA (Evil computer viruses)
• Shota Aizawa VS...
  • Osamu Dazai (Mentors from anime who can nullify other abilities. Additionally, Aizawa's combat tape visually resembles Dazai's bandages)
  • Qrow Branwen (Unexpectedly ordinary-looking Badass Teachers)
• Shrek vs...
  • Manny (CGI film-series protagonists who starts off as grumpy loners before reluctantly befriend an annoying animal whom they rescued and escort someone with the animal's help which causes them to open up and even start a family)
  • Sulley (Iconic heroic CGI movie monsters who both debuted in 2001 and originally start off by scaring others to maintain their lifestyles, but later have a change of heart)
• Shulk vs...
  • Diavolo (A battle of future sight, with one being able to change fate while the other believes fate is inescapable)
  • Euden (Blond-haired, sword-wielding protagonists of Action RPGs published by Nintendo with boisterous bruisers as their best friends, continuously pursue a female loved one throughout their adventures, are fragments of the Gods of their respective universes, and end their adventures by slaying said God).
  • Lightning (Sword-wielding protagonists from Japanese RPG series who go from humble beginnings to fight against the gods they once followed, fight to avenge their loved ones after they lost their lives due to monsters attacking their home [although they later reunite with their lost loved one, in an alternate form], and after defeating the god they once followed, used their powers to make a world for humanity alone)
  • Raziel (Undead swordsmen who wield living swords, have English accents, are connected to a malevolent and ancient entity, whose main motivation in their game is to seek out Revenge, and who eventually decide to Screw Destiny)
  • She-Ra (Netflix) (Protagonists who are chosen wielders of legendary weapons only they can wield at full potential that grant them great power who also find out that they are meant to be weapons of destruction before eventually having to use replicas of their weapons)
  • Taskmaster (Swordsmen with insane prediction skills)
• Shuma-Gorath vs. Starro (Marvel vs. DC fight of powerful entities with similar physical traits [having one eye and tentacles] who seek to rule over everyone)
• Shuten-Douji vs. Noshino (Oni women summoned by the protagonist to aid their cause, battle against alien and supernatural beings that threaten the world and timeliness, originate from a past era of Japan [Heian and Showa periods], dual wield swords in agile styles, one of said swords are bigger than their bodies [greatsword and nodachi], are quickly infatuated with the protagonist and becoming a potential wife to them, are pretty teasing to said main character, and in-ganr they can boost their teammates. In contrast Shuten-Douji is lazy and barely ever takes things seriously while Noshiro is overworker that's always responsible in her work, Shuten wears little clothing while Noshiro is pretty conservative, and Shuten origins as one of Japan's great calamities while Noshiro's creation purpose is as a defender of humanity)
• Shyvana vs. Volga (Half-dragons in heavy Crimson armors, specialize in Pyrokinetic Melee, and can transform into a dragon.
• Sinestro vs...
  • Pennywise (Powerful beings that both embody fear and get stronger the more people fear them)
  • Yuuki Terumi (Former heroes who betrayed their allies for their own benefit, lead evil organizations, get more powerful the more people fear them, and become beast-like entities in their most powerful state [Parallax for Sinestro, Susanoo for Terumi])
  • Zamasu (Tyrannical, god-like beings who were once part of a peace-keeping order before later betraying them due to desiring to rule the universe themselves, were temporarily removed from their universes before returning even stronger than ever before, wear powerful rings, fight alongside an extension of themselves [Parallax for Sinestro, Goku Black for Zamasu], and fight against and are later defeated by a hero who is part of a powerful group [Hal Jordan with the Green Lanterns, Goku with the Saiyans] that humiliated them in the past)
• Sif vs. Zacian (Giant dogs who fight with swords that they hold in their mouths that continue to protect what they were tasked with acting guardians of, even long after their masters are gone)
• Simon Belmont vs...
  • Miriam (Whip-wielding demon slayers of 2D action games who are affected by a curse that slowly kills them. Also a case of original vs Spiritual Successor)
  • Rinko Kougyoku (The first protagonist of their series, and their main antagonist is a dark magic user)
  • Sir Arthur (protagonists of Nintendo Hard horror-themed action platformer franchises)
• Skeletor vs...
  • Lord Zedd (Comedic yet powerful villains who act as the original and de-facto main antagonist of a long-running franchise who command their own armies of darkness and wield staffs)
  • Mumm-Ra (undead-themed villains whose respective archenemies (He-Man and Lion-O) have already fought each other in Death Battle)
• Skull Kid vs. Infinite (Mask-wearing antagonists from Japanese video games that were once unassuming members of their species until gaining an artifact that can warp reality [Majora for Skull Kid, the Phantom Ruby for Infinite])
• Skull Knight vs. the First Hassan (Powerful, imposing knights who are coated in armor [including a skull-like helmet], existed for centuries, are not afraid to kill, are gruff with a kind heart, save the protagonist from dark deities, and are referred to with royal aliases)
• Skye vs...
  • Owlette (Pink-clad high flyers from two popular preschool shows that actually have plenty of stuff that would be useful in combat. Both of them also have wind attacks, and the original female members of their respective teams)
  • Peridot (Flying dogs who can create tornadoes)
  • Zaheer (Normal Nickelodeon characters who gained the power of wind)
• Sly Cooper vs...
  • Catwoman (Thieves who despite finding themselves on the wrong side of the law tend to be more akin to anti-heroes than anything else, with their crimes rarely, if ever moving past theft, and have a complicated relationship with their main pursuers [Batman and Carmelita Fox, respectively] with whom they share a love-hate relationship with)
  • Rouge (Anthropomorphic animals who are professional thieves who recovered numerous treasures from around the world and are the leaders of a team of three [The Cooper Gang and Team Dark, respectively] and have had run-ins with the authorities and have actually worked for them as well [Sly teaming up with Carmelita on multiple occassions and Rouge being a G.U.N. agent])
• The Snatcher vs...
  • The Devil (Indie game villains who are themed around contracts and soul collecting)
  • Flowey (Once kindhearted princes who were wrongfully murdered, then returned from the dead as evil, soul-sucking monsters with a dark sense of humor and some medium awareness)
• The Sniper vs...
  • Captain Boomerang (Mercenaries from countries in Oceania that specialize in long-range weaponry and work in groups of fellow mercenaries, with the former being quiet and reserved while the latter is a stereotypically loud and reckless Jerkass)
  • Daisuke Jigen (Calm gunslingers who keep their heads and hats down while acting as snipers for their teams)
  • Marquis (snipers from hero shooters, with the former being an honorable figure who is mistaken as a common criminal while the latter is a sadistic serial killer with the appearance of a gentleman)
• Solidus Snake vs. Führer King Bradley (One-eyed leaders of military groups who seek to defend their country and wield swords)
• Soldier: 76 vs...
  • Mr. Incredible (Once popular heroes who became outcasts and biligantes after the downfall of heroic organizations and the populace growing to dislike them, with the former attacking criminals and resenting the world and his past while the latter saved lives in secret and longing to become loved by the masses again)
  • The Soldier (Rocket-launching soldiers who also have "soldier" in their alias from rivalling team-based soldiers, with the former having regrets about his past while the latter embraces it)
  • Yokai (Formerly respected old man who faked his death out of a desire to punish those he believed wronged him, adopting a more violent approach that causes his former colleagues to lose their respect for him)
• Sombra vs...
  • Aiden Pearce (Master hackers from modern video games)
  • Lucy (Hackers from 207X)
  • Marcus Holloway (Young master hackers, the former a villain, the latter an Anti-Hero)
  • Skye (purple-clad Stealth Experts who utilize a cloaking device)
  • Wrench (Master hackers working for a team, and are also quite huge Trolls)
• Sophitia Alexandra vs...
  • Boudica (Swordswomen that fight with Knightly Sword and Shields, have a responsible, elder sister-like vibe, partake in long travels in search of ways to secure their families, have great belief in the Greek gods, are capable of shooting beams from their swords, and a feeling of regret for failing on their missions)
  • Xingcai (Women from long-running franchises who crossed paths before that fight in a Knightly Sword and Shield style, have great loyalty to their nations, have a Sibling Yin-Yang relationship with their siblings with them being The Stoic, and make use of elemental attacks [Sophitia with electricity and Xingcai with wind])
• SpaceGodzilla vs. Ultraman Belial (Dark reflections of classic kaiju-fighting heroes who were corrupted by extraterrestrial meddling)
• Spider-Man Noir vs. Flashpoint Thomas Wayne (Darker and Edgier Alternate Universe Anti-Hero versions of Spider-Man and Batman respectively)
• Spike Spiegel vs...
  • Brock Samson (One-Man Army companions)
  • Revy (Anime mercenaries who are toughened anti-heroes who are often regarded to be among the greatest gun-slingers in anime history, mostly traveling around on a ship sharing the same name of their series. Both are part of a 4-person crew of other outlaws where they have the designated niche as the main marksmen; said crew composes of a big burly guy, a techie, and a new recruit whom they initially didn't get along with but then they eventually become a sort of love interest. Additionally, both have nicknames based on their fighting styles ("Swimming Bird" and "Two-Hands") and are often seen smoking a cigarette throughout their series in a set-up that is basically a "slice-of-life but with guns" premise, fighting against mob crews, teaming up with other bounty hunters, and completing life-risking odd job missions)
  • Ryo Saeba (anime gunslingers)
  • Space☆Dandy (Space Western protagonists made by Studio Bones)
• Spinal vs...
  • Cervantes de Leon (Undead pirates from fighting games, with the former being a hero and the latter a villain)
  • Fangore (fighting game skeletons with swords)
  • Sir Daniel Fortesque (Skeletal swordsmen)
• The Spinosaurus vs. the Giganotosaurus (Giant carnivorous theropods who serve as the Final Boss of Jurassic Park film trilogies who defeat a Tyrannosaurus rex before losing a rematch with one in a 2022 work [The Spinosaurus who losing against Big Eatie and Little Eatie and surviving, while the Giganotosaurus lost against Rexy and the Therizinosaurus and died])
• Splinter vs. Shifu (rodent Old Masters and expert martial artists)
• Sportacus vs...
  • Charles Barkley (sports-themed superheroes [the latter retains his superpowered Adaptational Badass status])
  • Chase (blue superhero speedsters who star on shows that aired on Nickelodeon, save lives, use tennis balls as weapons, have young boys and girls to help them, are heavily associated with a pink girl, mainly protect a town, and oppose a goofy villain dressed in purple)
  • LeBron James (sports-themed superheroes [the latter retains his superpowered Adaptational Badass status])
• Sprig Plantar vs. Mio (Deuteragonists who travel with the two people they’re closest to [Polly and Hop Pop for Sprig, Taion and Sena for Mio] as well as people from different worlds and have a special connection with the protagonist in particular [Anne and Noah respectively], have a connection to a woman who was once close to the main villain [Leif and M respectively], and eventually have to leave the protagonist in order to return to their original world)
• Sprout Cloverleaf vs. Clarence (The main antagonists of 2021 CGI films [My Little Pony: A New Generation and Extinct]. Both are voiced by Ken Jeong. Both have red as one color [Sprout's body and Clarence's shirt]. Both despise entire species [Sprout despises unicorns and pegasi, while Clarence despises Flummels]. And both destroyed the protagonists' homes via mechanical means [a war machine and bomb respectively])
• The Spy vs...
  • The Imposter (Stealthy assassins who rely on disguising themselves)
  • Loid Forger (Cold War-era secret agents known for their near-perfect ability to disguise themselves as other people who have to contend with family issues)
  • Revenant (Violent, stealthy assassins from team-based shooters, with the former being surprisingly caring to their allies while the latter is a remorseless killing machine)
  • Riki (Valve characters who're invisible backstabbers)
  • Sombra (Stealth-based fighters from rival team-based shooters who specialize in sabotaging the enemy team)
  • Twitch (French secret agents who work for an internationally-run organization, wear ski masks, and specialize in using disruptive gadgets)
• Squall Leonhart vs...
  • Qrow Branwen (Gun-blade wielding swordsmen who seem to be born unluckly on a quest to save the world from an evil witch)
  • Ruby Rose (Protagonists who train at an academy for warriors and wield blade-gun hybrid weapons)
  • Tatsuya Suou (Stoic, sword-wielding protagonists with a lion motif, who are later discovered to have had a childhood friendship with their party members that they've all forgot due to a traumatic event)
  • Yoh Asakura (Warriors who use spirits to enhance themselves)
  • Yu Narukami (Leaders of a group of teens who fight with summons)
• Stain vs...
  • Copen (Superhero killers with contrasting arsenals: Stain uses a katana and knives while Copen uses a ranged arsenal)
  • Onomatopoeia (East vs. west fight of two superhero-killing antagonists who turned to a life of crime after being mutilated by a superhero, are expert marksmen, and hold a level of respect for those who bested them [Deku for Stain, Batman for Onomatopoeia)
• Star Dream vs...
  • The Biolizard (Artificial creatures that were originally made for the sake of saving their creator's daughter [Gerald to find a cure to Maria's illness. Haltmann to find a way to get Susie back after she was accidentally sent to another dimension in an experiment], but had their purposes corrupted after their master went insane [Gerald to destroy the planet and Haltmann to mechanize all planets in the galaxy], with both Star Dream and Biolizard taking that second goal and merging themselves with a space station to achieve it, ending with the heroes defeating them in space)
  • Jubileus (Reality-warping final bosses planning to wipe out all life in the universe)
  • The Savior (White, non-organic final bosses who serve as their respective organizations' power sources, absorb the main antagonists to be activated, and are defeated by the efforts of two main characters)
• Starfire vs. Lum Invader (Superpowered Alien Princesses who are in relationships with their male leads)
• Star-Lord vs. Adam Strange (Marvel vs. DC fight starring their respective Captain Space, Defender of Earth!-esque space rangers)
• Starlight Glimmer vs. Amon (Villains who despise individuality and take it away. Though Starlight is reformed and moved on, Amon embodies his biggest inner demon)
• Sterling Archer vs...
  • Austin Powers (Deconstructive Parodies of James Bond)
  • Stan Smith (Anti heroes with ties to secret agencies)
• Steve vs...
  • Captain Olimar (explorers of open-world games)
  • Emmet Brickowski (Blocky protagonists who can create anything)
  • Maxwell (Protagonists in popular games that are imaginative)
  • Sackboy (Microsoft vs. Sony fight featuring protagonists from games centered around creating and sharing creator-built worlds)
  • The Terrarian (Emotionless player characters who explore and fight against a world trying to kill them by gathering materials and making weapons and houses)
  • The Villager (Blank-faced avatars who have similar designs and come from games that revolve around gathering items and building a town)
• Stormfront vs...
  • Baron Zemo (Supervillains who are relics of the Nazis' influence in the modern age and are themed in some fashion around lightning, with Baron Zemo starting off as purely evil before becoming an Anti-Villain while Stormfront only put on the image of a hero to hide their true, malicious ambitions)
  • Crossbones (Xenophobic right-hands of villainous organizations who have a close connection to their commanders, with the former being a seemingly noble superhuman who hides her true intent, while the latter actively shows his racist ideals and uses traditional weaponry)
• Strider Hein vs. Storm Shadow (White-clad ninjas who betrayed their peace-keeping clan to join a villainous, technologically-advanced organization and fought against their former best friend)
• Sucy Manbavaran vs. En (Wizards of dubious morality with obssesions for mushroom base spells)
• Sui-Feng vs. Milo (No-nonsense captains of organizations in charge in protecting the world, have insect motifs [bees and scorpions respectfully], and make use of One-Hit Kill attacks)
• Suika Ibuki vs...
  • Ibaraki-Douji (Small, blonde Onis with great fighting capabilities despite what their appearances may tell at first who are insane Hard Drinking Party Girls [despite that Ibuki Can't Hold Her Liquor, while Suika who's a Drunken Master])
  • Shuten-Douji/Ibuki-Douji (Both are Gender Flips of the original Shuten-Douji)
• Supaidaman vs...
  • Batman Ninja (Japanese versions of Spider-Man and Batman respectively)
  • Sixties Batman (Less serious and more goofy versions of Spider-Man and Batman respectively)
• Super-Adaptoid vs. Amazo (Marvel vs. DC fight of robots who fight against and copy the powers of an entire team of superheroes)
• Super Mecha Death Christ vs. Mechakara (Super-powered humanoid robots from web series starring Caustic Critics)
• Super Soldier vs. Soldier Supreme (alternate versions of Captain America amalgamated with different superheroes)
• Swamp Thing vs. Man-Thing (Marvel vs. DC battle of powerful swamp monsters made of greenery and can control plants with "-Thing" in their names)
• Sylvanas Windrunner vs...
  • Ashe (Female leaders who enter combat as cloaked rangers wielding sorcery alongside their bow and arrows; meta-wise, Ashe is an indirect Expy of Sylvanas due to her being an Expy of the Drow Ranger, who reused Sylvanas's model)
  • Sarah Kerrigan (Female protagonists turned antagonists from video game series owned by Blizzard Entertainment, being once noble warriors who were corrupted by dark forces to become a major antagonist in their series)

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