They have developed their own in-house Universal System for RPGs called 2d20 that is built around a core mechanic of rolling under the total of Attribute + Skill on two d20s.
Games published by Modiphius include:
- Achtung! Cthulhu
- Achtung! Cthulhu Skirmish
- Shadows over Normandie
- Cohors Cthulhu
- Black Void
- Brik Wars
- City of Mist
- Cogs Cakes And Swordsticks
- Cold And Dark
- Conan Adventures In An Age Undreamed Of - RPG based on Conan the Barbarian
- Dishonored Roleplaying Game - RPG based on Dishonored
- Dune Adventures In The Imperium - RPG based on Dune
- Dust Adventures - RPG based on the Dust strategy games
- The Elder Scrolls: Call to Arms - Miniature game based on The Elder Scrolls
- Elite Dangerous Role Playing Game - RPG based on Elite Dangerous
- Fallout Wasteland Warfare - Miniature game based on Fallout
- Fragged Empire
- Free League Publishing - Modiphius produces English language editions of their games.
- Freeway Warrior
- Homeworld Revelations - RPG based on Homeworld
- Infinity The Roleplaying Game - RPG based on Infinity miniatures game.
- John Carter Of Mars Adventures On The Dying World Of Barsoom - RPG based on John Carter of Mars
- KULT: Divinity Lost - Reboot of KULT
- Kung Fu Panda The Board Game - Board Game based on Kung Fu Panda
- Legacy Life Among The Ruins
- Liminal
- LUGU - An abstract storytelling Card Game
- Mindjammer
- Mutant Chronicles - Published through May 2022, when they opted to not renew their license.
- Siege of the Citadel
- Nibiru
- Odyssey of the Dragonlords - A campaign for Dungeons & Dragons
- Raiders of the Serpent Sea - A campaign for Dungeons & Dragons
- Rangers of Shadow Deep Deluxe Edition - Special edition of the miniatures game from Joseph A. McCullough that incorporates the rules update, some of the supplementary material, and additional artwork.
- Space 1889
- Star Trek Adventures - RPG based on Star Trek
- Thunderbirds Co Operative Board Game - Board Game based on Thunderbirds
- Unity
- Vampire: The Masquerade 5th Edition
