One may refer to:
- The One and Only Index, for tropes centered on the number "1".
- ONE. — the creator of One-Punch Man and Mob Psycho 100.
- ONE. — the manhwa.
- ONE. — the web animation.
- One (1997) — the PlayStation video game.
- ONE (2019) — a fanmade sequel for the game OFF.
- One: Kagayaku Kisetsu e — the Japanese visual novel developed by Tactics, also known as ONE.
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