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  • In the Baldur's Gate series, a male player character can have this relationship with his childhood friend Imoen, who is the most loyal of all the potential companions. No matter what, she will stick with the PC because of her friendship for him. In an unmodded game, there is never any hint of attraction between them (and some expanded banters will have her be Squicked by the thought). In fact, Baldur's Gate II reveals that a male PC and Imoen aren't just like brother and sister, they actually are (though she had a different mother). This has not stopped modders and shippers from pairing them up, especially since their Divine Parentage makes it highly unlikely they're biologically related.
  • Castlevania:
    • At the beginning of Castlevania: Portrait of Ruin, Jonathan Morris states that his childhood friend Charlotte Aulin is like his dear sister, much to her displeasure since she doesn't like to be treated like a child.
    • In Castlevania: Order of Ecclesia, Albus views himself as Shanoa's big brother, complete with Knight Templar Big Brother tendencies. Whether or not Shanoa feels the same is uncertain since we don't see much of her prior to her memory loss.
  • Lucca insists that her relationship with Crono is like this in Chrono Trigger. Whether or not that's entirely true is a matter of some speculation.
  • The members of the Detectives United seem to be developing this bond with one another as the series progresses. Both Agent Brown and Anna seem to regard James as an honorary kid brother of sorts, and he looks up to the two of them (mostly); Brown also has a lot of respectful deference for Anna much like a big sister. The fourth installment makes it clear that they'll do just about anything to protect each other.
  • Disgaea 6: Defiance of Destiny: Zed and Bieko are both zombies and the two simply happened to have been risen in the same graveyard, and for as long as they can remember, they've only had each other while everyone else did nothing but bully them all the time. Eventually, the two became like brother and sister, with Bieko affectionately calling Zed "Bubby" and Zed dedicating his life to becoming the best big brother in the universe for Bieko.
  • In the Dragon Age games, the player character can develop this sort of dynamic with any companion of the opposite sex that they don't actively romance.
    • One of the most pronounced examples is in Dragon Age: Inquisition; should a female Inquisitor max out the approval rating of the Tevinter mage Dorian, their dialogue clearly indicates a mutual platonic adoration.
    • Also in Inquisition, there are shades of this trope in the relationship between Cullen and Cassandra. It's made very clear that they like, respect, and trust one another in a non-romantic way; furthermore, listening in on ambient dialogue with the runners who deliver messages around Skyhold shows that she has a tendency to watch him closely. She's monitoring him for signs that his lyrium withdrawal is getting to him, but they both express this fact in ways that make her sound more like a big sister than anything. He has a similar relationship with Josephine and Leliana, though to a lesser extent; they tease him about his hair and his romance with a female Inquisitor, and have a number of other kindly sibling-like interactions with him.
  • Dragon Quest XI: Due to the fact that his mother had acted as a Parental Substitute for her when she was young, Jade explicitly views the Luminary as her little brother. That said, the player is given the option to marry her in the Switch version of the game. She also states that she felt a sisterly affection toward Hendrick and Jasper, alongside whom she grew up when they were knights-in-training. When Hendrick joins the party in the present, there are shades of this kind of relationship, as he acts as the stern but caring older brother to her rambunctious and rowdy younger sister.
  • In The Elder Scrolls V: Skyrim, the Dragonborn can join the Companions, a warrior guild stationed in Whiterun which effectively takes the place of the Tamrielic Fighters' Guild from the previous games. All of the members of the Companions refer to one another as "Shield-Brother" and "Shield-Sister," and most if not all of them consider the guild to be their true family.
    • The Skyrim chapter of the Dark Brotherhood also consider themselves a family, and could describe most of their relationships with each other in this way. They don't voice it as explicitly as the Companions, but it's there.
    • In the Dawnguard expansion, a male Dragonborn can develop this sort of bond with Serana, since she's not available (outside of mods) as a romance option.
    • This may also be a description of the relationship between a female Dragonborn and Paarthurnax. On a metaphysical level, they actually are brother and sister, both having been created by Akatosh, the god of time; depending on how the Dragonborn chooses to view Paarthurnax's mentorship, it could certainly fall into this trope.
  • Final Fantasy:
    • Zidane and Freya from Final Fantasy IX. She's the only female he doesn't actively flirt with (the fact that she already has a one true love helps) and they have a mutual respect and camaraderie from the beginning.
    • Final Fantasy X:
      • Tidus and Rikku. Rikku is the first person Tidus is able to talk to in Spira and they form a really close bond over the course of their journey. Yuna and Wakka also as they grew up together on Besaid. She actually says that she and Wakka (as well as Lulu) are brother and sister. Wakka also says at one point that Yuna is a like a little sister to him and Lulu, and their interactions back that up.
      • Tidus and Lulu in a way become this as well. Lulu is initially cynical towards Tidus when he joins the group but she is always the one who tells him about Spira and she has definitely warmed to him by the time they get to Guadosalam.
    • Vaan and Penelo appear to be this initially in Final Fantasy XII, but the end of the game implies that they might be more.
    • Serah and Noel in Final Fantasy XIII-2 form a brother-and-sister like relationship through the course of the game due to both having their own love interests already (Noel being in love with Yuel and Serah being Snow's fiancé).
  • They're actually stated to be cousins, but the relationship between James and Rachel in Haunted Hotel: The Evil Inside comes across more like this. It's especially pronounced in the bonus chapter, which reveals that Rachel cherishes a photo of the two of them hugging. Rachel later returns in the final installment, A Past Redeemed, to serve as the maid of honor in James's wedding - suggesting that she's also very close to his bride Jessica and may have even introduced the two of them.
  • In I Was a Teenage Exocolonist, Rex and Nomi-Nomi describe their friendship since they were kids as a close siblinglike bond. Rex may cuddle Nomi-Nomi a lot, but if you ask them if they're dating, they'll clarify that they're not. In fact, Nomi-Nomi isn't interested in Rex "that way" because the former is demisexual, but they eventually realize that they're crushing on him if Sol bonds with Nomi well enough and supports their budding relationship.
  • In Kingdom Hearts Sora seems to have a special bond with Ariel. They are certainly much closer than Sora is with the other Disney characters who appear in various worlds. Especially in the first game, Ariel's desire to see other worlds is paralleled with Sora's same desire from the beginning. There would be good justification for a romantic pairing, except Ariel is canonically paired with Eric in the second game (just like the movie) while Sora has overt feelings for Kairi, with the two becoming an Official Couple in the third game.
  • In Knights of the Old Republic II: The Sith Lords, in a conversation with Mira regarding the Love Triangle with him, Visas Marr, and the Handmaiden, a male Exile can express that the Handmaiden is like a little sister to him. It's taken even farther by the revelation that his surrogate mother Kreia is her actual mother.
  • Life Is Strange: Victoria Chase and Nathan Prescott have a close platonic relationship, and Victoria is probably the only person in the world who genuinely cares about what he's going through. Unfortunately, she has little ability to actually help him, between his father refusing to allow him the therapy he needs and Mark Jefferson manipulating him by pretending to act as his father figure. She can tell that he's getting worse over the course of the game, but doesn't know what to do. If Max tries to talk to her about how dangerous Nathan is getting, she'll eventually decide that Nathan needs to be brought in for his own good.
  • If Wrex survives Virmire and you turn down the Salarian Dalatrass's request to fake the genophage cure, his relationship with Shepard in Mass Effect 3 is this. He even calls Shepard brother/sister at the end of "Priority: Tuchanka." He goes out of his way to not call his biological half-brother as such, because Wreav's an asshole.
  • In Overwatch's first short story, "Bastet", the narration mentions that Ana Amari, Jack Morrison and Gabriel Reyes were like siblings to each other during Overwatch's golden years. In the present, Jack and Ana are still close friends, but Gabriel has undergone a Face–Heel Turn (becoming Reaper) and is now their enemy. Also Jack was later confirmed to be gay, killing any possible history between him and Ana.
  • Persona:
    • Junpei and Yukari's relationship in Persona 3 is basically this, along with a healthy dose of Vitriolic Best Buds. They tease each other mercilessly, but also respect and care about each other a lot, with no sign of romantic interest.
      • In the PSP re-release, unless you have him be your lover, Akihiko can form this kind of bond with the female protagonist, courtesy of his new Social Link. It's even more sibling-like insofar as late in the link, he'll admit that he sees his deceased younger sister Miki in the protagonist. The female protagonist and Junpei also fall into this, especially seeing as Junpei can't be romanced: their relationship in their Social Link is entirely platonic with Junpei taking on a protective brother role towards her; Junpei's canon romance with Chidori conflicts with a possible romance.
    • Much like the above Persona 3 example, Persona 5 has Futaba and the main protagonist, Joker. Due to sharing a parental figure in Sojiro, both of them spend a great amount of time around Leblanc with each other playing video games, reading manga and eating curry, eventually culminating in this trope being solidified if Joker chooses to remain platonic instead of pursuing a Relationship Upgrade. Fan works that heavily support this pairing often use this as a way to keep Joker and Futaba close to each other while having both of them pursue other romantic relationships. One of the new optional scenes in Royal even lets Joker introduce her to another character by saying "she's basically my sister."
  • In Potion Permit, Socellia enjoys seeing Russo and Laura get along like siblings, with the former protecting the latter like a big brother.
  • Roots of Pacha
    • Voda and Garrek, both only children, enjoy each other's company to the point that the former considers the latter like her brother.
    • According to Jukk, his mother Okka sees Zelk like a brother, and Jukk sees his friend Ibon the same.
  • In Sands of Destruction, Agan and Morte are Childhood Friends. Kyrie seemed a bit down at first that his pretty Love Interest has such a close male friend, but it soon becomes obvious that while Agan frets over Morte and she will kill anyone who hurts him, their relationship is that of siblings. It isn't stated exactly where Morte's parents are or what happened to them, but when visiting the Bacchitav Caravan, they're not there and she's clearly on good terms with Agan's mom, perhaps implying that they were actually raised as siblings.
  • Duncan Wu and the Player Character from Shadowrun Returns: Hong Kong. They grew up on the street together, got adopted by the same man, and lived under the same roof for their entire teens. Even after the PC ran away from home and spent an eight-year stint in prison, during which the two had no contact, it's clear Duncan cares for them upon the two re-uniting in Hong Kong, although it takes him a while to forgive you for the 'running away' part. Banters with Duncan are rife with sibling-like ribbing and snark, and Duncan is the one member of the crew who will always try to ground the Player Character in the life they left behind when forced to become Shadowrunners.
  • Shantae: Shantae has this relationship with her old friend Bolo. For better or for worse, this means she's more or less off of Bolo's radar.
  • In the Sonic the Hedgehog series, Tails and Amy act like this. Amy's Stalker with a Crush status can make things a bit tense, however.
    • Shadow and Maria also had this relationship.
    • On the official Japanese website for Sonic the Hedgehog (2006), Blaze and Silver's relationship was stated to be like this.
  • Falco Lombardi and Katt Monroe from Star Fox. They're not related, but they've known each other for most of their lives. Their once-ambiguously-portrayed relationship turned out to be this once it became clear in Farewell, Beloved Falco that Falco isn't into girls (or at the very least isn't looking for a girlfriend), but they have a sibling-like loyalty to each other.
  • Tales Series:
    • Though it's never outright stated, Yuri and Estelle in Tales of Vesperia fall into this. Despite numerous Shipper on Deck moments from other companions in various skits, they never stray from being like brother and sister.
    • The same case can also apply with the main hero and heroine of Tales of Graces. Despite the traditional romantic feelings harboring between the Tales of... heroes, this time, the main character's love interest isn't the main heroine (who unfortunately is hit hard by some fans), so despite the numerous Ship Tease moments, nothing romantic ever occurs between the two of them. It doesn't help that the main heroine isn't even human. In the Lineage to the Future arc, Asbel explicitly refers to Sophie like a sister (although in a skit, she refers to him like a father-figure as well — It Makes Sense in Context).
      • Eventually, Asbel adopts Sophie into his family — not as his sister, but as his daughter.
      • Graces also seems to be invoking this trope with one of its win quotes. Asbel refers to himself, his brother, and Cheria — who clearly harbours romantic interests for him — as "Lhant's Triplets of Terror." Cheria angrily retorts, "I am not your sister, Asbel!"
  • Xenoblade Chronicles:
    • Xenoblade Chronicles 2: Unlike the other main Driver/Blade relationships in the game, which lean more towards romance (aside from Nia and Dromarch), Tora and Poppi’s relationship is portrayed as being much more sibling-like. They fight and annoy each other frequently, yet despite all of that, they are inseparable, and will do just about anything to protect each other.
    • Xenoblade Chronicles 3: Lanz and Sena, compared to the other Ouroboros pairs. Noah and Mio are an Official Couple while Taion and Eunie get Ship Tease, but while Lanz and Sena clearly care for each-other and have a Birds of a Feather dynamic, neither shows interest in romance once they're introduced to the concept, and their interactions remain close but platonic.

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