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  • Yakumo from 3×3 Eyes is immortal. The only way to kill him would be to kill Pai, and if you lay even a single finger on her, Yakumo gets unlimited power, meaning his healing ability becomes instantaneous and he can use his attack spells without restriction. Unfortunately, the same applies to his nemesis Benares, who also has the advatage of being a vastly more powerful Dragon God in human form who invented the Summon Magic used by Yakumo, making him an even more dangerous example.
  • Ajin: Sato is technically nothing more than a human with military training who can't die (and can sometimes summon a sort of battle ghost), but his sociopathy and love of action are so extreme that he will do absolutely anything to get a thrill in battle. What makes him scary is his resourcefulness: try to kill him, lock him, incapacitate him, he will find a way to turn the table on you by some insane and unpredictable method that takes advantage of his immortality. That includes chopping his own hand, sending it in a food-delivery package to the building he wants to infiltrate, grinding himself to smithereens in a wood-cutting machine, and then reappearing inside the building when his body regenerates from the previously chopped-off hand. In other words, he effectively died and let a double of himself replace him. No one seems able to stop him for more than a minute.
  • Attack on Titan: The Female Titan. Her relentless pursuit of Eren leaves a gruesome path of death and destruction in her wake, and is our first glimpse of just how terrifying humans with a Titan form truly are. She has the highest body count of any single Titan in the series, making her More Deadly Than the Male in so many ways.
  • Creed in Black Cat has some Phletbotinum juice that repairs his body from anything as long as there remains a single surviving cell of his DNA. To stop him takes a Phlebotinum bullet that can destroy every cell of his body, but because the one who fired it was a merciful sweeper who does not kill people it only hit him in the wings. More Phlebotinum, this time in the form of a syringe was used this time to destroy the nanomachines that made him implacable in the first place.
    • In the original manga, Creed's only weakness is his brain, and Train would need to shoot him in the head (which would kill him, which Train refuses to do) in order to stop him. Otherwise, he's unbeatable. He takes Train's best shot, a stronger version of the attack that flattened Shiki, and gets up without a scratch. Instead, Train wins by breaking Creed's Imagine Blade (which is linked to his mind), and then having Eve purge his nanomachines while he's incapacitated.
  • Roberta from Black Lagoon, who in the space of two episodes hunts the protagonists through half of Roanapur, implacably getting through, in order, one shoot-out against twenty people all intent on killing her, the building said shoot-out was taking place in being detonated (by her, while she was inside, no less!), the ensuing inferno, a car chase that ends with her car flying from a rooftop and crashing into the side of a building, hanging onto the protagonists' car with a knife as they try to shake her off at top speed, being flung from said car into the side of a cargo container, a shootout with the Dark Action Girl heroine and finally a several-hour long fistfight. Which she stands up and walks away from after drawing with a Cross Counter. And she's a maid by profession.note 
    • Lampshaded when the Lagoon Company directly compare her to the Terminator.
    • The El Baile de La Muerte manga arc/Roberta's Blood Trail OVA sees her go beyond even this, the whole arc being a one-woman killing spree against everyone standing in her way. In the OVA, is permanently crippled, losing a leg, an eye, two fingers on her right hand and the entire left arm to Grey Fox... And yet she keeps coming, though by the end it's ambiguous who is the hunted and who is the hunter.
  • Blame! by Tsutomu Nihei has plenty. For one, there are Safeguard agents who can not be killed, only temporarily disabled/blown into pieces/vaporized, as they actually reside in virtual reality and can create remotely controlled bodies anywhere where a certain device is nearby. Oh, and they can instantaneously generate endless amounts of brainless robot Mooks who have razor sharp claws that cut metal like hot butter, are near impervious to conventional weaponry, and are really really fast and insanely strong. And then there's Killy, Artificial Human who walks through the whole world to find what he is looking for and is really really really durable. He was once buried under tons of molten metal and concrete and his near indestructible flesh was burned to his bone, but give him 14 years and he recovered completely, ready to continue his walk.
  • Bleach:
    • The Espada. One of them takes the hero's ultra-powerful, last-ditch attack which has defeated his previous opponents with ease... and gets off with a slight burn. He's not even the most powerful. Their leader, Captain Aizen, also does this: he effortlessly blocked the hero's best attack using one finger. The finger didn't even bleed.
    • Zaraki Kenpachi, who just grins after being impaled multiple times, and lets someone stab him just so he can get close enough to stab back.
  • Almost every Awakened Being in Claymore. They do eventually die from Monster Threat Expiration, but boy do they take a lot of punishment. Some Claymores can as well. The Abyssal Ones are the worst of them, but they were eventually wiped out by even worse Implacable Women, namely the abyssal feeders, who were specifically designed to be relentless killers for the Abyssal Ones by the Organization, and Priscilla, who is obviously even stronger and more Implacable than the Abyssal Ones.
  • Apocryphos from D.Gray-Man DEFINITELY counts as one. He or "It" is a sentient Innocence whose sole purpose is to protect the "Heart" of Innocence but upon his debut, his goal changes to assimilating Allen Walker although seeing as how he states he wants to do this to suppress the Fourteenth, this could also constitute as protecting the heart. How far is It willing to go to achieve Its goal? It infiltrated the Black Order as a yet unnamed Cardinal; "killed" Cross Marian who has so far been shown as the strongest and certainly most Bad Ass Exorcist; erased the memories of countless stooges; wiped Howard Link's memory and nearly killed him too if it hadn't been for a timely save; fought off two Noah simultaneously while trying to absorb Allen, damaging Road to the point that her "dream" was broken and she disappeared; has stalked Allen Walker for the past 3 months NONSTOP, through different cities and possibly countries; and most recently curb stomped Yu Kanda, erased his memories of the brief ordeal and may have killed Timcampy. And It's still going.
  • Den-noh Coil has the anti-virus program Satchii, a Killer Rabbit who relentlessly hunts down Illegal programs and illegal program users. Satchii and the little mechanical balls, Kyuu-chans, that come from him, are the general bane of the main characters of Den-noh Coil. But once his limits are learned and Satchii becomes familiar, the even-more unstoppable version 2 hunters show up!
  • Dragon Ball:
    • After Piccolo shows up, villains often come in this variety. Any time a villain is more powerful than the heroes, said heroes will momentarily get an opening and attack at full force, only for it not to work, even when they make a direct hit. Smoke Shields are often used to give the impression that the villains are no more, but come on. They'll always be fine.
    • Cell can regenerate all wounds and come back if there is even a single cell of his body left.
    • Majin Buu. He's been destroyed and vaporized, only to reform in the smoke and goes on to easily destroy Earth and nearly every character in the series.
    • Recoome from the Ginyu Force. He gets thrashed by Vegeta, takes a ki blast to the face, and while firing his Eraser Gun, Krillin knees Recoome in the back of the head. This makes him abruptly close his mouth, causing the Eraser Gun to blaze out of his nostrils! And each time, he gets right back up with ease, showing no fatigue whatsoever. Vaporized body armor, torn-up jump suit, small blood stains on his face, some patches of hair on his head were missing, and some teeth were lost... that's all Vegeta and Krillin managed to do to him. It was to the point that when Goku showed up and took down Recoome with one hit, everyone was having a hard time believing what they just witnessed!
    • For heroic example, Goku during his raid on the Red Ribbon Army to obtain two of the Dragon Balls. Nothing the army did could stop him. He shrugged off sniper fire, side-stepped rocket launchers, took down jets and tanks, could take out dozens of soldiers at once, and deflect bullet fire. Not even the ceiling crushing him or a giant power suit could stop Goku. The horrors he struck within the army inspired Dr. Gero to create the androids and Cell.
    • Spopovich, who lost quickly to Mr. Satan in the 24th World's Martial Arts Tournament, has become one in the 25th Tournament, where he No Sells every one of Videl's hits before he proceeds to pound her into the floor. The Z Fighters would've been able to beat him, but they don't get the chance, as the Supreme Kai needs him alive so that he'll able follow him back to his boss Babidi, and when he does return to his master's ship, Babidi decides that Spopovich has outlived his usefulness.
    • Jiren of Universe 11 is widely regarded as the most powerful mortal in the multiverse. He's one of the few opponents Goku is unable to match even at Super Saiyan Blue, as well as someone that Hit's Time Stop was unable to help him keep up with. Not even using Time Freeze was able to slow him down. The only thing that ever genuinely did serious harm to Jiren was Ultra Instinct, and the only way to defeat him was with a Ring Out to disqualify him from tournament he was competing with the heroes in rather than by actually physically incapacitating him.
  • Diclonius in Elfen Lied are practically immune to bullets (they won't even slow them down) thanks to a large number of invisible hands that block them. They are not invincible when fighting each other however.
  • Yamato from Eyeshield 21 is an inverted example. He's a fullback who wants to get away from the opposing defence and the simple fact that he can't get away from them isn't going to stop him, even if he has to drag the entire defence along with him.
  • Fate/stay night:
    • Berserker had 12 lives and easily took any damage dished out to him. In the end it took some Phlebotinum to kill him. By easily took the damage we don't mean "he tanked that sword in the gut like a boss" we mean "unless that sword was at least an A-rank magical artifact it didn't even bruise his skin"... and that's before Berserker starts tanking hits like a boss.
    • Souren Araya, a Buddhist monk who's been alive for 200 years. He has charms embedded in his body, allowing him to take blows that would otherwise kill him. Cut off his arm? He regenerates it without a problem. Cut off his other arm? It'll strangle you. Stab him? He won't even get wounded. Stab him in his point of death? No effect. Stab him in his point of death a second time after falling off a building? He's still alive for around 10 more minutes to converse with Touko before fading away to dust. His origin is stillness, after all.
    • The second half of the second season of the Spin-Off Fate/kaleid liner PRISMA☆ILLYA features Bazett, who tanks everything from Luvia's Battle Butler who uses More Dakka and grenades, to a room full of gems without even so much as dirtying her nice suit. And this doesn't even involve the use of her trump card Fragarach. This is rather egregious, because Berserker above lost one life to a mere handful of gems, making her even tankier than he is.
  • Kenshiro of Fist of the North Star might be a Bruiser with a Soft Center, but as the Zeed Gang, the Fang Clan, and Jackal's gang found out, nothing will stop him in his pursuit of oppressors. Not even intervening skyscrapers, which he just walks through.
  • Every homunculus from Fullmetal Alchemist, thanks in part to their Philosopher's Stone giving them unbelievable regeneration powers. Some specific examples include:
    • Lust gets shot several times, exploded, and has her Philosopher's Stone forcibly yanked from her chest by Roy, and keeps on going. If Alphonse and Roy hadn't promptly cornered her and applied liberal amounts of flame, respectively, they'd all have been toast.
    • Then there's Greed!Ling unleashing his fury toward Amestris soldiers after Bradley killed Fuu, his trusted bodyguard. There's a reason Greed got called "Ultimate Shield".
  • Ryudou Hishiki from Get Backers. To get you an idea of how an Implacable Man he is, in a later chapter of the manga, he's chasing Ban and Ginji on a granny's bicycle at over 100 km/h, all while tossing around police cars out of the way!
  • The Necrolyzed dead in Gungrave are invincible and always get back up even when riddled with bullets. Yes even the mooks. Their muscles continue to move even when it should be physically impossible. The series' protagonist is one as well. Brandon 'Beyond the Grave' Heat won't stop until he settles his score with Harry.
  • Psycho for Hire Natasha Radinov from the Gunsmith Cats OVA is directly compared to the Terminator. With a Batman-esque bulletproof coat that lets her shrug off small arms fire, she easily storms through a police safehouse and mows down a dozen or so officers and federal agents, before surviving an exploding car plummeting into a river. It takes Rally magdumping into her at close range while she's recovering from May's flashbangs to put her down for good.
  • Almost all of Hellsing's non-humans, including the mooks, and at least one empowered human count as Implacable Men. Hails of normal rounds barely faze them and they heal almost instantly.
    • One extreme case is Church Militant Father Alexander Anderson, who takes two headshots from explosive .454 bullets in rapid succession and gets back up almost immediately.
    • Another is Designated Hero and somewhat Friendly Neighborhood Vampire Alucard, who gets shot to pieces on three separate occasions only to rise, heal and mop the floor with his assailants. Admittedly, both of the above are anti-heroes instead of villains, but the bad guys do get their own Implacable Men, including aforementioned army of vampire mooks.
    • The Big Bad has on his side a Werewolf who's practically Made of Iron and a Catboy by the name of Schrödinger. He got his head shot off in England. He showed up in Brazil in the time it took the Big Bad to walk down the hall. That "dead" thing? It got better. And there's the good guy's former Battle Butler Walter, as a vampire.
  • JoJo's Bizarre Adventure:
    • Tarkus from Phantom Blood proves to be this, shrugging off any damage done to him while delivering a grueling Curb-Stomp Battle onto Jonathan, with Zeppeli's sacrifice being the only thing capable of turning the tables.
    • Battle Tendency:
      • Straizo, after becoming a vampire at the beginning of the Part, takes the vampire's Healing Factor to its absolute limits. Being riddled with bullets from a Tommy Gun and completely blown up by multiple grenades only temporarily slows him down in his battle against Joseph.
      • The same Part shows another one with Kars, after he becomes the Ultimate Life Form. Now immune to almost everything, including the sun and the Ripple, and with the ability to transform any part of his body into any living thing (even when it's detached from his body,) he spends the final part of the story unrelentingly chasing Joseph (even when he steals a plane to escape) all the way to an active volcano. He gets cooked in the magma of said volcano and endures long enough to adapt his body to protect himself via an air barrier. It takes using the volcano to rocket him into space, where he freezes solid and drifts through the cosmos until he finally Goes Mad From The Isolation, to finally defeat him.
      • The Pillar Men in general have shades of this. Sunlight only petrifies them, and they need to be constantly exposed to it to keep them immobilized. Their skin is immune to the Ripple, meaning someone has to somehow puncture them and deliver the Ripple from inside, and they can absorb and digest any living thing via mere physical contact (though trying to do that to a Ripple User is a bad idea, as Joseph demonstrates against Santana). Even when someone has the means to hurt them, they're still extreme die-hards and refuse to go down (one even keeps going as a disembodied brain with tentacles).
    • Stardust Crusaders:
      • Pet Shop, DIO's villainous guard falcon. Despite having only one fight with Iggy, the bird makes itself clear that it will chase its target to the most unexpected places. Its relentless killing machine-like attitude also makes it comparable to the Terminators themselves.
      • DIO's Dragon, Vanilla Ice and his Stand, Cream. The inside of Cream's mouth is a void that destroys anything it swallows (except Ice himself), and it has the ability to turn itself inside out, effectively turning it into an invisible ball of void that simply erases whatever it runs into. Most of the fight against Ice is spent running away from him, and nobody lands a hit on him until he's already done quite a bit of damage, and even then, stabbing him through the mouth only seems to piss him off. This turns out to be because he's a vampire, which does let Polnareff figure out how to finally get rid of him: throw him into the sunlight.
    • Sheer Heart Attack, the Sub-Stand of Yoshikage Kira from Diamond is Unbreakable, a nearly indestructible tank that will always track the hottest object near it, and will not stop until its target has been destroyed.
    • Stone Ocean:
      • Yo-Yo-Ma, D an G's Stand, will stop at nothing to kill its targets, and thanks to its powerful Healing Factor, it can regenerate from just about any injury it takes.
      • Bohemian Rhapsody, Ungalo's Stand, brings characters from famous stories to life, which will then act as if they still were at the story they're from, and absolutely nothing can stop them from completing it.
    • Blackmore from Steel Ball Run, even after receiving fatal wounds, will not stop in his pursuit of the heroes, though this is mostly due to Catch the Rainbow plugging his wounds with water.
    • Tusk Act 4, the final evolution of Johhny's Stand, is this trope incarnate. When it can outright No-Sell a Time Stop, you know it's time to start running.
  • Ogami Ittō from Lone Wolf and Cub is a textbook (and particularly ruthless) example. He's a master assassin who completes the job no matter what — plenty of people have tried to stop him, but nobody succeeds. And that's not even getting into his personal goal of getting revenge on the Yagyu clan, second only to the Shogun in terms of overall power — they command legions of ninja and can force entire armies to obey their orders. Ittō cuts through every last thing they throw at him.
  • Lupin III is a franchise about the titular Gentleman Thief. The cop chasing him, Inspector Zenigata, is powered in his hunt by Justice. If he so much as lays an eye on Lupin, he'll start chasing the thief to the ends of the earth! Even killing him won't stop the Inspector. After being shot by the villain of Lupin III: Island of Assassins, he had been in coma for a while, and then his heart stopped. Upon seeing this, a fellow cop declared he would avenge Zenigata by capturing Lupin... And Zenigata promptly awakened from the coma, fully healed, trying to arrest Lupin, before returning to sleep.
  • The personified Book of Darkness in the Magical Girl Lyrical Nanoha A's. Her implacability was best displayed when Nanoha activated Raising Heart's brand new Deadly Upgrade, pierced the Book of Darkness' Deflector Shields, blasted her in the face with an Excelion Buster at point blank range... and didn't even leave a scratch on her.
  • Roberto and Inspector Lunge from Monster. One can wonder what sort of chaos would ensue should they ever have to face each other. They do. It's awesome.
  • Luna's father in My Bride is a Mermaid. The guy takes a Kill Sat to the face without even flinching.
  • Negima! Magister Negi Magi:
    • Has a variation that can only be described as...odd. Due to an unfortunate incident involving the Power Incontinence of the World Tree and a request for a kiss, Negi gets turned into an Implacable Man with the stated goal of french-kissing somebody, and the best efforts of several mages and fighters are powerless to stop him. He turned back to normal when he succeeds in kissing Asuna, nearly killing her by suffocation in the process.
    • Jack Rakan is the comedic version of this. The man will not go down, no matter how hard you hit him. One of his many titles is "That Damn Guy You Can Stab With Swords All You Like And It Won't Do A Thing Damnit", and for good reason. The Big Bad is forced to resort to use Reality Warper powers to erase him from existence to take him out, and he puts up quite a fight. Furthermore, Rakan comes back one more time AFTER his existance is erased to shake Negi back to his senses.
  • Himuro Genma from Ninja Scroll survives decapitation and more through his mastery of reincarnation. It takes being impaled by a roof timber and then covered in molten gold to finally stop him... for now at least. Theoretically, he may crawl out of the ocean someday as a homicidal gold-plated terror.
  • One Piece:
    • Luffy's rubber body and Determinator nature give him shades of this, particularly when upset. His fight against Arlong and more so against Enel — whose powers are useless against Luffy — are good examples where he keeps coming after them. Lately he's lost this status and goes to full Determinator since everybody they fight has a power that can hurt him. Notably, Luffy is very much this to Rob Lucci during their fight. Late during said fight, Lucci hits Luffy with his Rokuougan technique not once, not twice, but three times! The second one floors Luffy and it takes Usopp giving him a speech to stand up and fight, which gives him a Heroic Second Wind, but not before declaring to Lucci that he'll never fall to the ground again until he defeats him. Then, he gets hit by the third Rokuougan and it looks like it did the job, as we see Luffy collapsing... then stubbornly catching his footing and, with his last burst of strength, desperately unleashing Jet Gatling. Luffy defeats Lucci with this powerful attack (putting the latter into a coma) and surely enough, falls to the ground shortly after.
    • Mihawk was this to Krieg's crew — he single-handedly sank most of his 50-ship fleet, leaving the remains of his crew fleeing from Grand Line on the last remaining ship. Then he proceeds to track them down and cut their last ship in half — and all of it, just because he was bored. If Zoro didn't call him on a duel (thus giving him enough entertainment), he would probably finish them off. He comes back to that role in the Marineford, in which his fight with the main character consists him barely putting effort into attack, with said main character desperately trying to stay alive.
    • Smoker is like this to Luffy pre-Timeskip, back before Luffy could hurt Logia-types, and Smoker pursued Luffy relentlessly whenever their paths crossed and they weren't forced into an Enemy Mine scenario.
    • Due to being partially inspired by the Terminator, Bartholomew Kuma fits here, being an incredibly resilient cyborg and being able to redirect anything you throw at him. The short range teleportation and his primary method of movement being The Slow Walk just makes it worse.
    • Magellan, the prison warden of Impel Down. During Luffy's escape from prison, Magellan chases them the entire time, and it gets to the point that anybody that's caught by him is considered already dead as the prisoners run away from him, so what starts out as a riot of 5 floors and thousands of prisoners leads to less than 300 making it out alive. It's not that he's just unreasonably tough: his power is producing large amounts of poison, so that even touching him is suicide.
    • Though with that said, he did shrug off blows from Emporio Ivankov, which appeared to have bruised him up a bit but otherwise fine. He also took multiple cannon-fire like a cake-walk.
    • Soon after Admiral Akainu gives Magellan a serious run for his money. Like Magellan, touching him is suicide (made of lava), like Magellan he gives chase to the protagonists and no one seems to be able to stop him, only buy a little time before being defeated, and unlike Magellan he's actually made good on his promise to not let anyone escape by actually killing Ace.
    • Even after receiving the beating of a lifetime throughout the last hour, Doflamingo still has enough strength left in him to get back on his feet and search Dressrosa for Luffy, violently skewering anyone who gets in his way. The entire scene plays out like a horror movie as he furiously demands that Luffy show himself while impaled bodies hang about.
    • Jack of the Beast Pirates is an unreasonable brute who does not make requests: he makes demands. When he shows up in Zou, he tells the Minks to bring Raizo the ninja to him, and smashes a building when told they don't know who he's talking about and that he can search the island if he likes. He's not in Zou to search for Raizo, he's in Zou to find Raizo. If the Minks don't know where he is, then that's their own fault. Naturally things escalate into violence, and both the Musketeers and the Guardians take turns to fight Jack and his men for four days by shifting through day and night cycles. And no, there's no indication that Jack slept through any of it.
    • One she goes into one of her hunger pangs, Big Mom becomes virtually unstoppable. She cannot be reasoned with, she will push past any and all obstacles in her path by merely walking through them, and she absolutely will not stop until she's been fed the exact meal she's after. The climax of the Whole Cake Island arc has Big Mom pursue the Straw Hats for an entire day to retrieve a wedding cake they don't even have, with them throwing everything they have at her as they flee and only barely slowing her down, while her cooks scramble to actually bake the damn thing before Totto Land is destroyed in her wake.
  • Zombieman from One-Punch Man is this, and it's what gave him a spot in the S-Class despite not having the physical attributes to compete with the other S-Class heroes. As a zombie, he cannot die, does not need to eat, sleep, breathe or drink. A monster "killed" him 200 times, and he simply got up the 201st time and came right back to kill it.
  • Petopeto San has a character named Nuriko, who is a Nurikabe — Essentially, a wall monster. She is made of concrete. She only gets mad once, but the only way to stop her forward progress was to shove her off of the stage she was on at the time.
  • In Pokémon: Lucario and the Mystery of Mew, the Regis fit this trope to a T. No matter how many Aura Spheres Lucario chucks at them, and no matter how many passageways are knocked down, they just keep walking slowly, inevitably, towards the heroes. Especially interesting is the fact that they manage to be implacable even while being constantly pegged by their mutual weakness to Fighting-types.
  • Pokémon: Kyurem vs. The Sword of Justice, fifteenth movie, runs with this trope and combines it with Super-Persistent Predator for the titular Kyurem. The mon, in a fit of rage at their opponent fleeing, goes on a hellish chase throughout a good part of Unova to find Keldeo, pulverizing and freezing anything that even gets in his way. Any attempts to so much as stall him are absolutely ineffective.
  • Randel Oland of Pumpkin Scissors becomes an implacable man when he uses his blue lantern. The twist is that he's just a large, strong, completely human Gentle Giant — he gets injured like anyone else would. It's a good thing that most of his opponents are tanks crewed by rotten shots.
  • Ranma ½: Ryoga Hibiki takes this to Nigh-Invulnerable levels. Throughout the series, he has literally been smashed through solid concrete and through cliff walls and had the rubble collapse on top of him, only to emerge undaunted and continue to fight. More impressive, is his ability to traverse large distances on foot, in pursuit of his target and won't rest until he's caught up to them. Just ask Ranma.
  • Rebuild World:
  • Shishio Makoto, one of the Big Bads of Rurouni Kenshin. He goes through the entire cast without stopping, takes a hit from the hero's strongest attack and stands back up, you name it. It takes his own body overheating to kill him. To be specific, he takes a direct punch from Sanosuke, hit very hard by Saito's in the forehead, and that's not even including Kenshin's attacks...
  • Minako Aino in the manga version of Sailor Moon and her solo manga. Her greatest feat was when, after donating over a liter of blood while too young to do so, she finally found where the youma was and she climbed a large hospital in the middle of a heat wave to kill it, only taking the time to drink eight cans of tomato juice before the climb to restore her energies.
  • Sabrac from Shakugan no Shana. His physical humanoid form is only a small part of his actual body, so he's able to recover and regenerate from any attack.
  • Vassago Cassals aka POH from Sword Art Online. Almost nothing can put this guy down for good. Getting a severe beatdown by gives him a Torsowitha View, but he gets right back up as if nothing happened. He then gets frozen in ice by a Perfect Weapon Control Art, to which he breaks out using sheer willpower. The only way to put a stop to him is Kirito subjecting him to a Fate Worsethan Death by forcibly turning him into a tree and leaving him in the Underworld, and even that's hinted to not be enough, if his body disappearing from the Ocean Turtle with no explanation is anything to go by.
  • Tokyo Ghoul:
    • Noro, a strange and silent Ghoul working directly for Aogiri's leader. Even other ghouls consider his Healing Factor to be abnormal and his lack of reaction to damage disturbing. During the battle in the 11th Ward, he's pumped full of hundreds of rounds of ammunition without even reacting, and later is stabbed through the chest and then decapitated. He merely pulls himself together and is only stopped because he's apparently called back by his superiors. Noro seems to have two default settings: "Ignore Completely" and "Reduce to Chunky Salsa". In the sequel, he's finally put down for good......but only after the Quinx repeatedly blow him to pieces and Shirazu dies helping bring the monster down. It's then revealed that Noro was actually a mummified body kept going by Eto's powers.
    • Kishou Arima, the legendary "undefeated" Ghoul Investigator. Rather than simply shrugging off injury, he seems capable of dodging literally anything thrown at him and leaves his targets with a literal Run or Die scenario. Even the strongest of ghouls have no choice but to run as far and as fast as possible to survive an encounter with him. For this reason, ghouls call him Shinigami and consider him death incarnate.
  • Vash and Knives from Trigun, seeing as, in addition to just not dying, even when pushed to the very limit of their powers, they never relent in their ideals either. A potent example is when Vash fires a clip of bullets at Knives. Knives turns the parts of his body where the bullets hit into guns and fires back. They both recover.

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