Half Human Hybrids in Films — Live-Action.
- Alien: Resurrection has a half-human, half-Alien squickfest born from a Xenomorph Queen with a human reproductive system... who was laying eggs for the first two thirds of the movie.
- Aquaman (2018): Arthur is the son of an Atlantean mother and human father.
- The B-movie Arachnid has a gigantic alien spider giving birth to all kinds of other huge bugs. Sometimes it is required to lay the eggs inside a human. We never get any clue exactly what, if anything, it was mating with.
- In Beowulf (2007), Grendel is a Half-Human Hybrid. He may be sterile (given his apparent lack of reproductive organs), and though it may just be because he's a monster he gives a good impression of being sickly. He's hideously deformed, has what appears to be a nasty skin condition, and is sometimes heard whimpering as if in pain (though that's probably just because loud noises irritate his super-sensitive ear). The dragon at the end of the film is also a Half-Human Hybrid, born of a mating between Beowulf and Grendel's mother. This is also very much unlike the original poem, where no human ancestry was suggested for Grendel except that he was a distant descendant of Cain.
- In Beowulf & Grendel, Grendel is referred to as a troll but his mother is some sort of sea creature. His son with Selma is this trope played straight.
- The Live-Action Adaptation of Blood: The Last Vampire has the Dhampyr Saya, the daughter of a human and the vampire queen. She is over 400 years old, and has hunted many vampires during this period.
- Djinn: Khalid turns out to be the child of a female djinn and human man.
- In Dreamscape, Alex tries to help a young boy whose nightmares take the shape of a half-man/half-snake creature. Later, one of the villains also assumes this form while in the dream world.
- In The Erotic Rites of Frankenstein, Melissa is part bird, with green feathers along her arms and torso. She says that Cagliostro created her by impregnating a bird egg with human semen.
- The Golden Child has Kala, a half-dragon, half-human woman (it is stated that her mother was raped by a dragon) who spends most of her screentime hidden behind a screen and having her silhouette admired by Chandler. Unobscured, she has a serpentine lower half and a snakelike tongue.
- At the end of Guardians of the Galaxy (2014), Peter Quill is revealed to be human on one side and something else on the other. His father, Ego, plays a significant role in Guardians of the Galaxy Vol. 2. He's the Big Bad.
- Hansel & Gretel: Witch Hunters: Hansel and Gretel's mother turns out to have in fact been a (good) witch, which here is treated as a separate species. Their father was a normal human.
- In Hellboy (2019), it turns out that Hellboy himself is one. His father was a demon lord, his mother a mostly normal human woman.
- Jupiter Ascending:
- Caine, both genetically manufactured and half wolf. Stinger and Famulus also count, being half bee and half deer respectively.
- Technically, all of Earth is this way, Earth-humans having been spliced with native species during the seeding.
- Parodied in The Lost Skeleton of Cadavra. In one of the most lenient uses of "half", Animala is explicitly described as "half-woman, half-four different forest animals", specifically a fox, a squirrel, and two ferrets (not that you can really tell; she still looks like a normal woman who simply behaves like a very strange animal).
- Mythica: Dagen is a half-elf, son of an elven mother and an unknown human father.
- Alice in Seventh Son (2015) is the daughter of a human father and a witch mother (in the film, witches are implied to be a separate species). It turns out that the hero, Tom, is one as well.
- Barf the Mawg from Spaceballs. "I'm a Mawg. Half man, half dog. I'm my own best friend!" Even worse, the gangster Pizza the Hutt is described as half-man, half pizza. So that's how those Pizza Boy Special Delivery scenes really end...
- Partially justified in Species. While alien/human hybrids are created via Hand Wave, the three-quarters human children of The Virus-infected astronaut in Species II are sickly and (apparently) sterile. Patrick wants to mate with Eve in particular because she's a fertile half-hybrid.
- In Splice, two married scientists pioneer a new technology to 'plug and play' any number of different animal's DNA together to produce new unique organisms. They decide to take the next step and insert human DNA into the mix. That works out about as well as you would expect.
