In the Animorphs graphic novels, Tom's hair is the same shade of brown as Jake's. The original books describe them as looking very similar, except that Tom's hair and eyes are darker.
Rachel's sister Jordan is blonde like her, while the books say that she has brown hair like their mom.
In the 2004 BIONICLE comics, Vakama's lime green and Onewa's dark blue eyes are replaced with bright blue and orange visors respectively. Nidhiki's green eyes become red. The black and red Turaga Dume also turns black and gray, though that may be due to oddly placed shadows.
Queen Mauve is a blonde in the comic, but a redhead in the show. Her costume is changed from a blue and silver color scheme to a maroon and silver-grey one.
Stormfront has a red costume in the comic, in the show she has a dark red and black costume.
Soldier Boy has a Captain Patriotic red, white and blue costume in the comic. In the show he instead has a military green costume with black and gold embroidery.
Starlight has blue eyes in the comics, but has brown ones in the show.
Black Noir is blonde in the comic being a clone of Homelander, in the show he has dark hair getting a Race Lift and being unconnected to Homelander.
The Crow: in the transition from comic to the 1994 film, Shelly went from being blonde to brunette.
Hawk originally had blond hair in G.I. Joe: A Real American Hero (Marvel), but was given black hair in the animated series to distinguish him from Duke, the other blond-haired G.I. Joe leader (who actually appeared before Hawk in the animated series). The toyline followed suit by giving every Hawk action figure released afterward black or brown hair — except for the ones that came in comic packs in the 2000s.
G.I. Joe: Reloaded changes Roadpig so that his hair is red instead of white with red streaks.
The Hellboy franchise did this to Liz Sherman: Red hair in the comics, black in the live action movies, and some shade of brown in the animated movies.
Abe Sapien also received a color change, going from green-skinned in the comics to blue-skinned in the movies.
Highly likely changed to allow the Green Screen process to work.
The titular hero Mark has blue eyes in the comic (at least in the panels where his face is more detailed), while in the show he has brown eyes. This likely due to his mother Debbie getting a Race Lift being voiced by Sandra Oh making Mark biracial.
Eve in the comics has tangerine orange hair and bright green eyes, in the show she has reddish orange hair and bluish-green eyes.
Amber has blonde hair and blue eyes in the comics, in the show due to getting a Race Lift has dark hair and brown eyes instead.
Rex Splode has reddish hair and darker skin instead of the whiter skin and brown hair of his comic version. This also effects Robot when he gets a human body, in the comic he had light red hair whilst in the show he has dark reddish hair and dark skin due to taking DNA from Rex to create his new body.
Amanda aka Monster Girl has blue eyes and light brown hair in the comic, but instead has dark brown hair and grey eyes in the show.
Wendy Watson from The Middleman has orange hair in the original comic series, and was played by black-haired Natalie Morales in the TV series. The comic, which is actually set in the TV continuity, uses Morales' appearance.
Paper Girls: In the comics, Mac has red hair. Her actress Sofia Rosinsky is a brunette.
Salem was an orange cat for most of the series. The live action show made him into a more traditional black cat and gave him the ability to speak, both of which were implemented into the comics.
Sabrina herself traditionally has pale platinum blonde hair in the comics, but the live action TV show gave her golden blonde hair, which later carried over to the animated series and became her main hair color for much of the '90s and 2000s. 2010s comics differ on whether she has golden blonde or platinum hair. Chilling Adventures of Sabrina reconciles the two by showing that Sabrina was born with golden blonde hair (like her mother) but it lightened to a near-white shade of platinum blonde due to her being half-witch.
The comics' versions of Hilda and Zelda have red and green hair, respectively, but the live action show made them both blonde, while the animated series made Zelda the redhead and Hilda a brunette.
Sabrina's boyfriend Harvey has black hair in the comics, but light brown in both the sitcom and the cartoon.
Scott Pilgrim's ex-girlfriend Envy, lead singer of The Clash At Demonhead, was a redhead in the comic but a blonde in the film.
According to the back cover of Vol. 2, Todd Ingram is brown-haired , but he is blond-haired in the movie, and has orange hair in the game.
Gideon Graves has black hair in the comics, dark brown hair in the movie, and purple hair in the game.
Several of the characters who had black hair in the comics appear with purple hair in the game.
The Black Smurfs from The Smurfs story of the same name were changed to purple in the 1980sAnimated Adaptation and the Papercutz English translation of the original story. For the same reasons, the orange-skinned Swoofs from "The Astro Smurf" were changed to green in the cartoon show and the Papercutz English translation, and Grandpa Swoof's black hair was changed to white.
The nameless lord that the Smurfs meet in "The Hunger Of The Smurfs" had black hair, but when he became Mr. Poppery in the cartoon show adaptation "Haunted Smurfs", his hair was changed to gray.
Azrael himself gets a dye job in the 1980s cartoon show, with his orange fur changed to brown.
Princess Sally of Sonic the Hedgehog (Archie Comics) is quite the odd one. In Sally's first appearance, she was red-furred and blonde-haired. The very next issue, she was pink-furred and black-haired to match her Sonic the Hedgehog (SatAM) counterpart. However, that look was only used for the pilot episode. Then the cartoon settled on a brown-furred and auburn-haired combination and it would take about two years for the comic to catch up. Eventually, one comic explained this by revealing that she had fallen into a vat of chemicals while on a mission, and it took her a long time to properly wash it out of her fur.
Although Splinter's brown fur is usually kept in adaptations, it was turned gray for the second cartoon and IDW comics.
Also in the original underground Eastman and Laird comics, whenever the Turtles were depicted in color, their masks were uniformly red. They were colored coded for the kids' convenience in all other depictions except this one.
The early Mirage comics depicted April O'Neil with dark hair, which was changed to be a lighter auburn in the '80s cartoon. Her blue jumpsuit was also changed to be yellow, and she underwent a possible Race Lift (which has stuck to her modern incarnations).
Luther in the comic has white hair, in the show he’s got light brown hair.
Diego has blonde hair in the comic, but dark hair in the show due to being played by David Castaneda who’s Spanish.
Allison has got purple hair in the comic, in the show she has dark hair being played Emmy Raver-Lampman who’s black.
Klaus fitting his power, has a vampire tan in the comic while in the show he has normal Caucasian-coloured skin.
Vanya (now Viktor in the show) in the comic has an entirely white body upon getting her permanent Super Mode. In the show only their skin and goes white while their hair remains dark and it’s only when activating their power does his skin turn white at all.
Reginald Hargreeves has red hair in the comic, while in the show he has grey hair that was formerly brown. Subverted in both cases since it’s a really wig, as he’s a alien.